Autoimmunity to ACE2 as a possible cause of tissue inflammation in Covid-19

por Townsend, Alain
Publicado 2020

Murine Cytotoxic T Lymphocytes Recognize an Epitope in an EBNA-1 Fragment, but Fail to Lyse EBNA-1–expressing Mouse Cells

por Mukherjee, Siddhartha, Trivedi, Pankaj, Dorfman, David M., Klein, George, Townsend, Alain
Publicado 1998

Nonreplicating Influenza A Virus Vaccines Confer Broad Protection against Lethal Challenge

por Baz, Mariana, Boonnak, Kobporn, Paskel, Myeisha, Santos, Celia, Powell, Timothy, Townsend, Alain, Subbarao, Kanta
Publicado 2015

Tolerance in TCR/Cognate Antigen Double-Transgenic Mice Mediated by Incomplete Thymic Deletion and Peripheral Receptor Downregulation

por Mamalaki, Clio, Murdjeva, Marianna, Tolaini, Mauro, Norton, Trisha, Chandler, Phillip, Townsend, Alain, Simpson, Elizabeth, Kioussis, Dimitris
Publicado 1995

Characterization of Influenza Virus Pseudotyped with Ebolavirus Glycoprotein

por Xiao, Julie Huiyuan, Rijal, Pramila, Schimanski, Lisa, Tharkeshwar, Arun Kumar, Wright, Edward, Annaert, Wim, Townsend, Alain
Publicado 2018

Positive and Negative Selection in Transgenic Mice Expressing a T-Cell Receptor Specific for Influenza Nucleoprotein and Endogenous Superantigen

por Mamalaki, Clio, Elliott, James, Norton, Trisha, Yannoutsos, Nicholas, Townsend, Alain R., Chandler, Phillip, Simpson, Elizabeth, Kioussis, Dimitris
Publicado 1993

Lung-targeting lentiviral vector for passive immunisation against influenza

por Tan, Tiong Kit, Gamlen, Toby P E, Rijal, Pramila, Townsend, Alain R, Gill, Deborah R, Hyde, Stephen C
Publicado 2020

Cross-Neutralisation of Novel Bombali Virus by Ebola Virus Antibodies and Convalescent Plasma Using an Optimised Pseudotype-Based Neutralisation Assay

por Bentley, Emma M., Richardson, Samuel, Derveni, Mariliza, Rijal, Pramila, Townsend, Alain R., Heeney, Jonathan L., Mattiuzzo, Giada, Wright, Edward
Publicado 2021

Effects of Severe Acute Respiratory Syndrome Coronavirus 2 Strain Variation on Virus Neutralization Titers: Therapeutic Use of Convalescent Plasma

por Nguyen, Dung, Xiao, Julie, Simmonds, Peter, Lamikanra, Abigail, Odon, Valerie, Ratcliff, Jeremy, Townsend, Alain, Roberts, David J, Harvala, Heli
Publicado 2021

Distribution of Droplets and Immune Responses After Aerosol and Intra-Nasal Delivery of Influenza Virus to the Respiratory Tract of Pigs

por Martini, Veronica, Hinchcliffe, Michael, Blackshaw, Elaine, Joyce, Mary, McNee, Adam, Beverley, Peter, Townsend, Alain, MacLoughlin, Ronan, Tchilian, Elma
Publicado 2020

Characterization of neutralizing epitopes in antigenic site B of recently circulating influenza A(H3N2) viruses

por Beer, Kerstin, Dai, Mian, Howell, Steven, Rijal, Pramila, Townsend, Alain R., Lin, Yipu, Wharton, Stephen A., Daniels, Rodney S., McCauley, John W.
Publicado 2018

Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors

por Kandasamy, Matheswaran, Gileadi, Uzi, Rijal, Pramila, Tan, Tiong Kit, Lee, Lian N, Chen, Jili, Prota, Gennaro, Klenerman, Paul, Townsend, Alain, Cerundolo, Vincenzo
Publicado 2023

Comparison of two assays to detect IgG antibodies to the receptor binding domain of SARS‑CoV‑2 as a surrogate marker for assessing neutralizing antibodies in COVID-19 patients

por Kamaladasa, Achala, Gunasekara, Banuri, Jeewandara, Chandima, Jayathilaka, Deshni, Wijewickrama, Ananda, Guruge, Dinuka, Wijayamuni, Ruwan, Tan, T.K., Ogg, Graham S., Townsend, Alain, Malavige, Gathsaurie Neelika
Publicado 2021

A direct contact pig influenza challenge model for assessing protective efficacy of monoclonal antibodies

por McNee, Adam, Vanover, Daryll, Rijal, Pramila, Paudyal, Basudev, Lean, Fabian Z. X., MacLoughlin, Ronan, Núñez, Alejandro, Townsend, Alain, Santangelo, Philip J., Tchilian, Elma
Publicado 2023

Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses

por Tang, Qiannan, Rigby, Rachel E., Young, George R., Hvidt, Astrid Korning, Davis, Tanja, Tan, Tiong Kit, Bridgeman, Anne, Townsend, Alain R., Kassiotis, George, Rehwinkel, Jan
Publicado 2021

Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce Lung Pathology but Do Not Prevent Virus Shedding

por Paudyal, Basudev, McNee, Adam, Rijal, Pramila, Carr, B. Veronica, Nunez, Alejandro, McCauley, John, Daniels, Rodney S., Townsend, Alain R., Hammond, John A., Tchilian, Elma
Publicado 2021

Autophagy is a critical regulator of memory CD8(+) T cell formation

por Puleston, Daniel J, Zhang, Hanlin, Powell, Timothy J, Lipina, Elina, Sims, Stuart, Panse, Isabel, Watson, Alexander S, Cerundolo, Vincenzo, Townsend, Alain RM, Klenerman, Paul, Simon, Anna Katharina
Publicado 2014

Broadly Inhibiting Antineuraminidase Monoclonal Antibodies Induced by Trivalent Influenza Vaccine and H7N9 Infection in Humans

por Rijal, Pramila, Wang, Bei Bei, Tan, Tiong Kit, Schimanski, Lisa, Janesch, Philipp, Dong, Tao, McCauley, John W., Daniels, Rodney S., Townsend, Alain R., Huang, Kuan-Ying A.
Publicado 2020

Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus

por Chang, Pengxiang, Lukosaityte, Deimante, Sealy, Joshua E., Rijal, Pramila, Sadeyen, Jean-Remy, Bhat, Sushant, Crossley, Sylvia, Daines, Rebecca, Huang, Kuan-Yin A., Townsend, Alain R., Iqbal, Munir
Publicado 2022

Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation

por Rahikainen, Rolle, Rijal, Pramila, Tan, Tiong Kit, Wu, Hung‐Jen, Andersson, Anne‐Marie C., Barrett, Jordan R., Bowden, Thomas A., Draper, Simon J., Townsend, Alain R., Howarth, Mark
Publicado 2020