Towards Precision Oncology: The Role of Smoothened and Its Variants in Cancer

por Nicheperovich, Alina, Townsend-Nicholson, Andrea
Publicado 2022

Teaching genomics to life science undergraduates using cloud computing platforms with open datasets

por Poolman, Toryn M., Townsend‐Nicholson, Andrea, Cain, Amanda
Publicado 2022

An Ensemble-Based Protocol for the Computational Prediction of Helix–Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular Dynamics

por Altwaijry, Nojood A., Baron, Michael, Wright, David W., Coveney, Peter V., Townsend-Nicholson, Andrea
Publicado 2017

Rapid and accurate assessment of GPCR–ligand interactions Using the fragment molecular orbital‐based density‐functional tight‐binding method

por Morao, Inaki, Fedorov, Dmitri G., Robinson, Roger, Southey, Michelle, Townsend‐Nicholson, Andrea, Bodkin, Mike J., Heifetz, Alexander
Publicado 2017

Hit-to-lead and lead optimization binding free energy calculations for G protein-coupled receptors

por Wan, Shunzhou, Potterton, Andrew, Husseini, Fouad S., Wright, David W., Heifetz, Alexander, Malawski, Maciej, Townsend-Nicholson, Andrea, Coveney, Peter V.
Publicado 2020

An Immunological Approach to Increase the Brain's Resilience to Insults

por Lin, En-Ju D., Symes, C. Wymond, Townsend-Nicholson, Andrea, Klugmann, Matthias, Klugmann, Claudia B., Lehnert, Klaus, Fong, Dahna, Young, Deborah, During, Matthew J.
Publicado 2014

Characterizing Interhelical Interactions of G-Protein Coupled Receptors with the Fragment Molecular Orbital Method

por Heifetz, Alexander, Morao, Inaki, Babu, M. Madan, James, Tim, Southey, Michelle W. Y., Fedorov, Dmitri G., Aldeghi, Matteo, Bodkin, Michael J., Townsend-Nicholson, Andrea
Publicado 2020

The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle

por Ren, Meixia, Ng, Fu Liang, Warren, Helen R, Witkowska, Kate, Baron, Michael, Jia, Zhilong, Cabrera, Claudia, Zhang, Ruoxin, Mifsud, Borbala, Munroe, Patricia B, Xiao, Qingzhong, Townsend-Nicholson, Andrea, Hobbs, Adrian J, Ye, Shu, Caulfield, Mark J
Publicado 2018