Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders

por Danckwardt, Sven, Trégouët, David-Alexandre, Castoldi, Elisabetta
Publicado 2023

Small Open Reading Frames, How to Find Them and Determine Their Function

por Kute, Preeti Madhav, Soukarieh, Omar, Tjeldnes, Håkon, Trégouët, David-Alexandre, Valen, Eivind
Publicado 2022

miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

por Marchand, Alexandre, Proust, Carole, Morange, Pierre-Emmanuel, Lompré, Anne-Marie, Trégouët, David-Alexandre
Publicado 2012

Design and Rationale of the ERA-CVD Consortium PREMED-CAD—Precision Medicine in Coronary Artery Disease

por Shrivastava, Apurva, Marzolla, Vincenzo, Weidmann, Henri, Caprio, Massimiliano, Tregouet, David-Alexandre, Zeller, Tanja, Karakas, Mahir
Publicado 2020

Common and Rare 5′UTR Variants Altering Upstream Open Reading Frames in Cardiovascular Genomics

por Soukarieh, Omar, Meguerditchian, Caroline, Proust, Carole, Aïssi, Dylan, Eyries, Mélanie, Goyenvalle, Aurélie, Trégouët, David-Alexandre
Publicado 2022

Sex-specific effect of CPB2 Ala147Thr but not Thr325Ile variants on the risk of venous thrombosis: A comprehensive meta-analysis

por Zwingerman, Nora, Medina-Rivera, Alejandra, Kassam, Irfahan, Wilson, Michael D., Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Gagnon, France
Publicado 2017

Effects of Genetically Determined Iron Status on Risk of Venous Thromboembolism and Carotid Atherosclerotic Disease: A Mendelian Randomization Study

por Gill, Dipender, Brewer, Christopher F., Monori, Grace, Trégouët, David‐Alexandre, Franceschini, Nora, Giambartolomei, Claudia, Tzoulaki, Ioanna, Dehghan, Abbas
Publicado 2019

Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events

por Ojeda, Francisco M., Müller, Christian, Börnigen, Daniela, Trégouët, David-Alexandre, Schillert, Arne, Heinig, Matthias, Zeller, Tanja, Schnabel, Renate B.
Publicado 2016

OPTIMIR, a novel algorithm for integrating available genome-wide genotype data into miRNA sequence alignment analysis

por Thibord, Florian, Perret, Claire, Roux, Maguelonne, Suchon, Pierre, Germain, Marine, Deleuze, Jean-François, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre
Publicado 2019

uAUG creating variants in the 5’UTR of ENG causing Hereditary Hemorrhagic Telangiectasia

por Soukarieh, Omar, Tillet, Emmanuelle, Proust, Carole, Dupont, Charlène, Jaspard-Vinassa, Béatrice, Soubrier, Florent, Goyenvalle, Aurélie, Eyries, Mélanie, Trégouët, David-Alexandre
Publicado 2023

GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, “GENEREPOL study”: Lack of common variants with large effect sizes

por Salem, Joe-Elie, Germain, Marine, Hulot, Jean-Sébastien, Voiriot, Pascal, Lebourgeois, Bruno, Waldura, Jean, Tregouet, David-Alexandre, Charbit, Beny, Funck-Brentano, Christian
Publicado 2017

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels

por Antoni, Guillemette, Oudot-Mellakh, Tiphaine, Dimitromanolakis, Apostolos, Germain, Marine, Cohen, William, Wells, Philip, Lathrop, Mark, Gagnon, France, Morange, Pierre-Emmanuel, Tregouet, David-Alexandre
Publicado 2011

The Choice of the Filtering Method in Microarrays Affects the Inference Regarding Dosage Compensation of the Active X-Chromosome

por Castagné, Raphaële, Rotival, Maxime, Zeller, Tanja, Wild, Philipp S., Truong, Vinh, Trégouët, David-Alexandre, Munzel, Thomas, Ziegler, Andreas, Cambien, François, Blankenberg, Stefan, Tiret, Laurence
Publicado 2011

Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patient...

por Kallel, Choumous, Cohen, William, Saut, Noémie, Blankenberg, Stefan, Schnabel, Renate, Rupprecht, Hans J, Bickel, Christoph, Munzel, Thomas, Tregouet, David-Alexandre, Morange, Pierre-Emmanuel
Publicado 2012

Blood pressure and risk of venous thromboembolism: a cohort analysis of 5.5 million UK adults and Mendelian randomization studies

por Nazarzadeh, Milad, Bidel, Zeinab, Mohseni, Hamid, Canoy, Dexter, Pinho-Gomes, Ana-Catarina, Hassaine, Abdelaali, Dehghan, Abbas, Tregouet, David-Alexandre, Smith, Nicholas L, Rahimi, Kazem
Publicado 2022

Multilocus Genetic Risk Scores for Venous Thromboembolism Risk Assessment

por Soria, José Manuel, Morange, Pierre‐Emmanuel, Vila, Joan, Souto, Juan Carlos, Moyano, Manel, Trégouët, David‐Alexandre, Mateo, José, Saut, Noémi, Salas, Eduardo, Elosua, Roberto
Publicado 2014

A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein

por Dusart, Philip, Fagerberg, Linn, Perisic, Ljubica, Civelek, Mete, Struck, Eike, Hedin, Ulf, Uhlén, Mathias, Trégouët, David-Alexandre, Renné, Thomas, Odeberg, Jacob, Butler, Lynn M.
Publicado 2018

Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis

por Thibord, Florian, Munsch, Gaëlle, Perret, Claire, Suchon, Pierre, Roux, Maguelonne, Ibrahim-Kosta, Manal, Goumidi, Louisa, Deleuze, Jean-François, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre
Publicado 2020

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans

por Codoni, Veronica, Blum, Yuna, Civelek, Mete, Proust, Carole, Franzén, Oscar, Björkegren, Johan L. M., Le Goff, Wilfried, Cambien, Francois, Lusis, Aldons J., Trégouët, David-Alexandre
Publicado 2016

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis

por Stritt, Simon, Nurden, Paquita, Nurden, Alan T., Schved, Jean-François, Bordet, Jean-Claude, Roux, Maguelonne, Alessi, Marie-Christine, Trégouët, David-Alexandre, Mäkinen, Taija, Giansily-Blaizot, Muriel
Publicado 2022