The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines?

por Ward, Brian J., Pillet, Stephane, Charland, Nathalie, Trepanier, Sonia, Couillard, Julie, Landry, Nathalie
Publicado 2018

Preclinical and Clinical Development of Plant-Made Virus-Like Particle Vaccine against Avian H5N1 Influenza

por Landry, Nathalie, Ward, Brian J., Trépanier, Sonia, Montomoli, Emanuele, Dargis, Michèle, Lapini, Giulia, Vézina, Louis-P.
Publicado 2010

Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine c...

por Dubé, Charlotte, Paris-Robidas, Sarah, Primakova, Iryna, Destexhe, Eric, Ward, Brian J., Landry, Nathalie, Trépanier, Sonia
Publicado 2022

Broad neutralization against SARS-CoV-2 variants induced by ancestral and B.1.351 AS03-Adjuvanted recombinant Plant-Derived Virus-Like particle vaccines

por Dubé, Charlotte, Paris-Robidas, Sarah, Andreani, Guadalupe, Gutzeit, Cindy, D'Aoust, Marc-André, Ward, Brian J., Trépanier, Sonia
Publicado 2022

Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adul...

por Pillet, Stéphane, Couillard, Julie, Trépanier, Sonia, Poulin, Jean-François, Yassine-Diab, Bader, Guy, Bruno, Ward, Brian J., Landry, Nathalie
Publicado 2019

Humoral and cell-mediated immune responses to H5N1 plant-made virus-like particle vaccine are differentially impacted by alum and GLA-SE adjuvants in a Phase 2 clinical trial

por Pillet, Stéphane, Aubin, Éric, Trépanier, Sonia, Poulin, Jean-François, Yassine-Diab, Bader, ter Meulen, Jan, Ward, Brian J., Landry, Nathalie
Publicado 2018

Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

por Ward, Brian J., Gobeil, Philipe, Séguin, Annie, Atkins, Judith, Boulay, Iohann, Charbonneau, Pierre-Yves, Couture, Manon, D’Aoust, Marc-André, Dhaliwall, Jiwanjeet, Finkle, Carolyn, Hager, Karen, Mahmood, Asif, Makarkov, Alexander, Cheng, Matthew P., Pillet, Stéphane, Schimke, Patricia, St-Martin, Sylvie, Trépanier, Sonia, Landry, Nathalie
Publicado 2021

Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in non...

por Pillet, Stéphane, Arunachalam, Prabhu S., Andreani, Guadalupe, Golden, Nadia, Fontenot, Jane, Aye, Pyone Pyone, Röltgen, Katharina, Lehmicke, Gabrielle, Gobeil, Philipe, Dubé, Charlotte, Trépanier, Sonia, Charland, Nathalie, D’Aoust, Marc-André, Russell-Lodrigue, Kasi, Monjure, Christopher, Blair, Robert V., Boyd, Scott D., Bohm, Rudolf P., Rappaport, Jay, Villinger, François, Landry, Nathalie, Pulendran, Bali, Ward, Brian J.
Publicado 2022

Safety and immunogenicity of an AS03-adjuvanted plant-based SARS-CoV-2 vaccine in Adults with and without Comorbidities

por Charland, Nathalie, Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Séguin, Annie, Makarkov, Alexander, Heizer, Gretchen, Bhutada, Kapil, Mahmood, Asif, Trépanier, Sonia, Hager, Karen, Jiang-Wright, Julia, Atkins, Judith, Saxena, Pooja, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Roman, François, Van Der Most, Robbert, Ceregido, Maria Angeles, Dionne, Marc, Tellier, Guy, Gauthier, Jean-Sébastien, Essink, Brandon, Libman, Michael, Haffizulla, Jason, Fréchette, André, D’Aoust, Marc-André, Landry, Nathalie, Ward, Brian J.
Publicado 2022

Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine

por Hager, Karen J., Pérez Marc, Gonzalo, Gobeil, Philipe, Diaz, Ricardo S., Heizer, Gretchen, Llapur, Conrado, Makarkov, Alexander I., Vasconcellos, Eduardo, Pillet, Stéphane, Riera, Fernando, Saxena, Pooja, Geller Wolff, Priscila, Bhutada, Kapil, Wallace, Garry, Aazami, Hessam, Jones, Christine E., Polack, Fernando P., Ferrara, Luciana, Atkins, Judith, Boulay, Iohann, Dhaliwall, Jiwanjeet, Charland, Nathalie, Couture, Manon M.J., Jiang-Wright, Julia, Landry, Nathalie, Lapointe, Sophie, Lorin, Aurélien, Mahmood, Asif, Moulton, Lawrence H., Pahmer, Emmy, Parent, Julie, Séguin, Annie, Tran, Luan, Breuer, Thomas, Ceregido, Maria-Angeles, Koutsoukos, Marguerite, Roman, François, Namba, Junya, D’Aoust, Marc-André, Trepanier, Sonia, Kimura, Yosuke, Ward, Brian J.
Publicado 2022