Protonation of a Glutamate Residue Modulates the Dynamics of the Drug Transporter EmrE

por Gayen, Anindita, Leninger, Maureen, Traaseth, Nathaniel J.
Publicado 2016

Inducing conformational preference of the membrane protein transporter EmrE through conservative mutations

por Leninger, Maureen, Sae Her, Ampon, Traaseth, Nathaniel J
Publicado 2019

Gatekeeper mutations activate FGF receptor tyrosine kinases by destabilizing the autoinhibited state

por Besch, Alida, Marsiglia, William M., Mohammadi, Moosa, Zhang, Yingkai, Traaseth, Nathaniel J.
Publicado 2023

Intrinsic Conformational Plasticity of Native EmrE Provides a Pathway for Multidrug Resistance

por Cho, Min-Kyu, Gayen, Anindita, Banigan, James R., Leninger, Maureen, Traaseth, Nathaniel J.
Publicado 2014

Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF

por Gao, Ang, Vasilyev, Nikita, Luciano, Daniel J, Levenson-Palmer, Rose, Richards, Jamie, Marsiglia, William M, Traaseth, Nathaniel J, Belasco, Joel G, Serganov, Alexander
Publicado 2018

Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket

por Wallon, Lauren, Khan, Imran, Teng, Kai Wen, Koide, Akiko, Zuberi, Mariyam, Li, Jianping, Ketavarapu, Gayatri, Traaseth, Nathaniel J., O’Bryan, John P., Koide, Shohei
Publicado 2022

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

por Chen, Huaibin, Marsiglia, William M, Cho, Min-Kyu, Huang, Zhifeng, Deng, Jingjing, Blais, Steven P, Gai, Weiming, Bhattacharya, Shibani, Neubert, Thomas A, Traaseth, Nathaniel J, Mohammadi, Moosa
Publicado 2017

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus

por Brawley, Douglas N., Sauer, David B., Li, Jianping, Zheng, Xuhui, Koide, Akiko, Jedhe, Ganesh S., Suwatthee, Tiffany, Song, Jinmei, Liu, Zheng, Arora, Paramjit S., Koide, Shohei, Torres, Victor J., Wang, Da-Neng, Traaseth, Nathaniel J.
Publicado 2022