Identification of Allosteric Modulators of Metabotropic Glutamate 7 Receptor Using Proteochemometric Modeling

por Tresadern, Gary, Trabanco, Andres A., Pérez-Benito, Laura, Overington, John P., van Vlijmen, Herman W. T., van Westen, Gerard J. P.
Publicado 2017

Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation

por Hell, Sandrine M., Meyer, Claudio F., Misale, Antonio, Sap, Jeroen B. I., Christensen, Kirsten E., Willis, Michael C., Trabanco, Andrés A., Gouverneur, Véronique
Publicado 2020

Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor

por Lavreysen, Hilde, Ahnaou, Abdellah, Drinkenburg, Wilhelmus, Langlois, Xavier, Mackie, Claire, Pype, Stefan, Lütjens, Robert, Le Poul, Emmanuel, Trabanco, Andrés A, Nuñez, José María Cid
Publicado 2015

Scaffold Hopping to Imidazo[1,2-a]pyrazin-8-one Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptor

por de Lucas, Ana I., Vega, Juan A., García Molina, Aránzazu, Linares, María Lourdes, Tresadern, Gary, Lavreysen, Hilde, Oehlrich, Daniel, Trabanco, Andrés A., Cid, José M.
Publicado 2021

Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological Characterization

por Doornbos, Maarten L. J., Wang, Xuesong, Vermond, Sophie C., Peeters, Luc, Pérez-Benito, Laura, Trabanco, Andrés A., Lavreysen, Hilde, Cid, José María, Heitman, Laura H., Tresadern, Gary, IJzerman, Adriaan P.
Publicado 2018

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

por Sap, Jeroen B. I., Straathof, Natan J. W., Knauber, Thomas, Meyer, Claudio F., Médebielle, Maurice, Buglioni, Laura, Genicot, Christophe, Trabanco, Andrés A., Noël, Timothy, am Ende, Christopher W., Gouverneur, Véronique
Publicado 2020

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

por Roagna, Giulia, Ascough, David M. H., Ibba, Francesco, Vicini, Anna Chiara, Fontana, Alberto, Christensen, Kirsten E., Peschiulli, Aldo, Oehlrich, Daniel, Misale, Antonio, Trabanco, Andrés A., Paton, Robert S., Pupo, Gabriele, Gouverneur, Véronique
Publicado 2020

Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches

por Rombouts, Frederik J. R., Alexander, Richard, Cleiren, Erna, De Groot, Alex, Carpentier, Michel, Dijkmans, Joyce, Fierens, Katleen, Masure, Stefan, Moechars, Diederik, Palomino-Schätzlein, Martina, Pineda-Lucena, Antonio, Trabanco, Andrés A., Van Glabbeek, Daan, Vos, Ann, Tresadern, Gary
Publicado 2017

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis

por Miles, Luke A., Hermans, Stefan J., Crespi, Gabriela A.N., Gooi, Jonathan H., Doughty, Larissa, Nero, Tracy L., Markulić, Jasmina, Ebneth, Andreas, Wroblowski, Berthold, Oehlrich, Daniel, Trabanco, Andrés A., Rives, Marie-Laure, Royaux, Ines, Hancock, Nancy C., Parker, Michael W.
Publicado 2019