Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding

por Trakselis, Michael A.
Publicado 2016

Amidst multiple binding orientations on fork DNA, Saccharolobus MCM helicase proceeds N-first for unwinding

por Perera, Himasha M, Trakselis, Michael A
Publicado 2019

Beyond the Lesion: Back to High Fidelity DNA Synthesis

por Kaszubowski, Joseph D., Trakselis, Michael A.
Publicado 2022

A hand-off of DNA between archaeal polymerases allows high-fidelity replication to resume at a discrete intermediate three bases past 8-oxoguanine

por Cranford, Matthew T, Kaszubowski, Joseph D, Trakselis, Michael A
Publicado 2020

Activity, substrate preference and structure of the HsMCM8/9 helicase

por McKinzey, David R, Li, Chuxuan, Gao, Yang, Trakselis, Michael A
Publicado 2023

Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding

por Graham, Brian W., Schauer, Grant D., Leuba, Sanford H., Trakselis, Michael A.
Publicado 2011

A trimeric DNA polymerase complex increases the native replication processivity

por Mikheikin, Andrey L., Lin, Hsiang-Kai, Mehta, Preeti, Jen-Jacobson, Linda, Trakselis, Michael A.
Publicado 2009

Characterization of a coupled DNA replication and translesion synthesis polymerase supraholoenzyme from archaea

por Cranford, Matthew T., Chu, Aurea M., Baguley, Joshua K., Bauer, Robert J., Trakselis, Michael A.
Publicado 2017

A multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress

por Griffin, Wezley C., McKinzey, David R., Klinzing, Kathleen N., Baratam, Rithvik, Eliyapura, Achini, Trakselis, Michael A.
Publicado 2022

Targeted chromosomal Escherichia coli:dnaB exterior surface residues regulate DNA helicase behavior to maintain genomic stability and organismal fitness

por Behrmann, Megan S., Perera, Himasha M., Hoang, Joy M., Venkat, Trisha A., Visser, Bryan J., Bates, David, Trakselis, Michael A.
Publicado 2021

Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment

por McKinzey, David R., Gomathinayagam, Shivasankari, Griffin, Wezley C., Klinzing, Kathleen N., Jeffries, Elizabeth P., Rajkovic, Aleksandar, Trakselis, Michael A.
Publicado 2021

Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

por Mohan, Swarna, Rizaldy, Ryan, Das, Debamitra, Bauer, Robert J., Heroux, Annie, Trakselis, Michael A., Hildebrand, Jeffrey D., VanDemark, Andrew P.
Publicado 2012

Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology

por Mohan, Swarna, Das, Debamitra, Bauer, Robert J., Heroux, Annie, Zalewski, Jenna K., Heber, Simone, Dosunmu-Ogunbi, Atinuke M., Trakselis, Michael A., Hildebrand, Jeffrey D., VanDemark, Andrew P.
Publicado 2013