Case report: Induction and maintenance of steroid-free remission with vedolizumab in a case of steroid-dependent autoimmune pancreatitis

por Griebel, Paul, Tran, Florian, Luehring, Janina, Schreiber, Stefan
Publicado 2023

Stem Cells and Organoid Technology in Precision Medicine in Inflammation: Are We There Yet?

por Tran, Florian, Klein, Christine, Arlt, Alexander, Imm, Simon, Knappe, Evelyn, Simmons, Alison, Rosenstiel, Philip, Seibler, Philip
Publicado 2020

External Model Performance Evaluation of Twelve Infliximab Population Pharmacokinetic Models in Patients with Inflammatory Bowel Disease

por Schräpel, Christina, Kovar, Lukas, Selzer, Dominik, Hofmann, Ute, Tran, Florian, Reinisch, Walter, Schwab, Matthias, Lehr, Thorsten
Publicado 2021

Dipeptidylpeptidase (DPP)-4 inhibitor therapy increases circulating levels of anti-inflammatory soluble frizzle receptor protein (sFRP)-5 which is decreased in severe COVID-19 dise...

por Brandes, Juliane, Zobel, Isabelle, Rohmann, Nathalie, Schlicht, Kristina, Geisler, Corinna, Hartmann, Katharina, Türk, Kathrin, von Schönfels, Witigo, Beckmann, Jan, Tran, Florian, Laudes, Matthias
Publicado 2022

Distinct Longitudinal Changes in Immunoglobulin G N-Glycosylation Associate with Therapy Response in Chronic Inflammatory Diseases

por Štambuk, Jerko, Vučković, Frano, Habazin, Siniša, Hanić, Maja, Novokmet, Mislav, Nikolaus, Susanna, Tran, Florian, Schreiber, Stefan, Franke, Andre, Rosenstiel, Philip, Lauc, Gordan, Aden, Konrad, Pezer, Marija
Publicado 2022

Patient Reported Outcomes in Chronic Inflammatory Diseases: Current State, Limitations and Perspectives

por Tran, Florian, Schirmer, Jan Henrik, Ratjen, Ilka, Lieb, Wolfgang, Helliwell, Philip, Burisch, Johan, Schulz, Juliane, Schrinner, Florian, Jaeckel, Charlot, Müller-Ladner, Ulf, Schreiber, Stefan, Hoyer, Bimba F.
Publicado 2021

Brief Research Report: Serum clara cell 16 kDa protein levels are increased in patients hospitalized for severe SARS-CoV-2 or sepsis infection

por Rohmann, Nathalie, Stürmer, Paula, Geisler, Corinna, Schlicht, Kristina, Hartmann, Katharina, Türk, Kathrin, Hollstein, Tim, Tran, Florian, Rosenstiel, Philip, Franke, Andre, Heyckendorf, Jan, Schreiber, Stefan, Schulte, Dominik M., Laudes, Matthias
Publicado 2022

Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections

por Schlicht, Kristina, Rohmann, Nathalie, Geisler, Corinna, Hollstein, Tim, Knappe, Carina, Hartmann, Katharina, Schwarz, Jeanette, Tran, Florian, Schunk, Domagoj, Junker, Ralf, Bahmer, Thomas, Rosenstiel, Philip, Schulte, Dominik, Türk, Kathrin, Franke, Andre, Schreiber, Stefan, Laudes, Matthias
Publicado 2020

Correction: Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections

por Schlicht, Kristina, Rohmann, Nathalie, Geisler, Corinna, Hollstein, Tim, Knappe, Carina, Hartmann, Katharina, Schwarz, Jeanette, Tran, Florian, Schunk, Domagoj, Junker, Ralf, Bahmer, Thomas, Rosenstiel, Philip, Schulte, Dominik, Türk, Kathrin, Franke, Andre, Schreiber, Stefan, Laudes, Matthias
Publicado 2021

Humoral protection to SARS-CoV2 declines faster in patients on TNF alpha blocking therapies

por Geisen, Ulf M, Sümbül, Melike, Tran, Florian, Berner, Dennis K, Reid, Hayley M, Vullriede, Lena, Ciripoi, Maria, Longardt, Ann C, Hoff, Paula, Morrison, Peter J, Schneider, Verena E, Zeuner, Rainald, Schirmer, Jan H, Steinbach, Andrea, Nikolaus, Susanna, Gerdes, S, Schreiber, Stefan, Bacher, Petra, Hoyer, Bimba F
Publicado 2021

Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis

por Bülck, Cynthia, Nyström, Elisabeth E. L., Koudelka, Tomas, Mannbar-Frahm, Michael, Andresen, Gerrit, Radhouani, Mariem, Tran, Florian, Scharfenberg, Franka, Schrell, Friederike, Armbrust, Fred, Dahlke, Eileen, Zhao, Bei, Vervaeke, Alex, Theilig, Franziska, Rosenstiel, Philip, Starkl, Philipp, Rosshart, Stephan P., Fickenscher, Helmut, Tholey, Andreas, Hansson, Gunnar C., Becker-Pauly, Christoph
Publicado 2023

Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort

por Geisen, Ulf M, Berner, Dennis K, Tran, Florian, Sümbül, Melike, Vullriede, Lena, Ciripoi, Maria, Reid, Hayley M, Schaffarzyk, Annika, Longardt, Ann C, Franzenburg, Jeanette, Hoff, Paula, Schirmer, Jan H, Zeuner, Rainald, Friedrichs, Anette, Steinbach, Andrea, Knies, Christine, Markewitz, Robert DH, Morrison, Peter J, Gerdes, Sascha, Schreiber, Stefan, Hoyer, Bimba F
Publicado 2021

Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease

por Mishra, Neha, Aden, Konrad, Blase, Johanna I., Baran, Nathan, Bordoni, Dora, Tran, Florian, Conrad, Claudio, Avalos, Diana, Jaeckel, Charlot, Scherer, Michael, Sørensen, Signe B., Overgaard, Silja H., Schulte, Berenice, Nikolaus, Susanna, Rey, Guillaume, Gasparoni, Gilles, Lyons, Paul A., Schultze, Joachim L., Walter, Jörn, Andersen, Vibeke, Dermitzakis, Emmanouil T., Schreiber, Stefan, Rosenstiel, Philip
Publicado 2022

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

por Aden, Konrad, Tran, Florian, Ito, Go, Sheibani-Tezerji, Raheleh, Lipinski, Simone, Kuiper, Jan W., Tschurtschenthaler, Markus, Saveljeva, Svetlana, Bhattacharyya, Joya, Häsler, Robert, Bartsch, Kareen, Luzius, Anne, Jentzsch, Marlene, Falk-Paulsen, Maren, Stengel, Stephanie T., Welz, Lina, Schwarzer, Robin, Rabe, Björn, Barchet, Winfried, Krautwald, Stefan, Hartmann, Gunther, Pasparakis, Manolis, Blumberg, Richard S., Schreiber, Stefan, Kaser, Arthur, Rosenstiel, Philip
Publicado 2018

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon

por Fazio, Antonella, Bordoni, Dora, Kuiper, Jan W. P., Weber-Stiehl, Saskia, Stengel, Stephanie T., Arnold, Philipp, Ellinghaus, David, Ito, Go, Tran, Florian, Messner, Berith, Henning, Anna, Bernardes, Joana P., Häsler, Robert, Luzius, Anne, Imm, Simon, Hinrichsen, Finn, Franke, Andre, Huber, Samuel, Nikolaus, Susanna, Aden, Konrad, Schreiber, Stefan, Sommer, Felix, Natoli, Gioacchino, Mishra, Neha, Rosenstiel, Philip
Publicado 2022

Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2

por Lipinski, Simone, Petersen, Britt-Sabina, Barann, Matthias, Piecyk, Agnes, Tran, Florian, Mayr, Gabriele, Jentzsch, Marlene, Aden, Konrad, Stengel, Stephanie T., Klostermeier, Ulrich C., Sheth, Vrunda, Ellinghaus, David, Rausch, Tobias, Korbel, Jan O., Nothnagel, Michael, Krawczak, Michael, Gilissen, Christian, Veltman, Joris A., Forster, Michael, Forster, Peter, Lee, Clarence C., Fritscher-Ravens, Annette, Schreiber, Stefan, Franke, Andre, Rosenstiel, Philip
Publicado 2019

Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease

por Ziegler, Jörn F., Böttcher, Chotima, Letizia, Marilena, Yerinde, Cansu, Wu, Hao, Freise, Inka, Rodriguez-Sillke, Yasmina, Stoyanova, Ani K., Kreis, Martin E., Asbach, Patrick, Kunkel, Desiree, Priller, Josef, Anagnostopoulos, Ioannis, Kühl, Anja A., Miehle, Konstanze, Stumvoll, Michael, Tran, Florian, Fredrich, Broder, Forster, Michael, Franke, Andre, Bojarski, Christian, Glauben, Rainer, Löscher, Britt-Sabina, Siegmund, Britta, Weidinger, Carl
Publicado 2019

Low-Avidity CD4(+) T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19

por Bacher, Petra, Rosati, Elisa, Esser, Daniela, Martini, Gabriela Rios, Saggau, Carina, Schiminsky, Esther, Dargvainiene, Justina, Schröder, Ina, Wieters, Imke, Khodamoradi, Yascha, Eberhardt, Fabian, Vehreschild, Maria J.G.T., Neb, Holger, Sonntagbauer, Michael, Conrad, Claudio, Tran, Florian, Rosenstiel, Philip, Markewitz, Robert, Wandinger, Klaus-Peter, Augustin, Max, Rybniker, Jan, Kochanek, Matthias, Leypoldt, Frank, Cornely, Oliver A., Koehler, Philipp, Franke, Andre, Scheffold, Alexander
Publicado 2020

The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination

por Saggau, Carina, Martini, Gabriela Rios, Rosati, Elisa, Meise, Silja, Messner, Berith, Kamps, Ann-Kristin, Bekel, Nicole, Gigla, Johannes, Rose, Ruben, Voß, Mathias, Geisen, Ulf M., Reid, Hayley M., Sümbül, Melike, Tran, Florian, Berner, Dennis K., Khodamoradi, Yascha, Vehreschild, Maria J.G.T., Cornely, Oliver, Koehler, Philipp, Krumbholz, Andi, Fickenscher, Helmut, Kreuzer, Oliver, Schreiber, Claudia, Franke, Andre, Schreiber, Stefan, Hoyer, Bimba, Scheffold, Alexander, Bacher, Petra
Publicado 2022

The long term vaccine‐induced anti‐SARS‐CoV‐2 immune response is impaired in quantity and quality under TNFα blockade

por Geisen, Ulf Martin, Rose, Ruben, Neumann, Franziska, Ciripoi, Maria, Vullriede, Lena, Reid, Hayley M., Berner, Dennis Kristopher, Bertoglio, Federico, Hoff, Paula, Hust, Michael, Longardt, Ann Carolin, Lorentz, Thomas, Martini, Gabriela Rios, Saggau, Carina, Schirmer, Jan Henrik, Schubert, Maren, Sümbül, Melike, Tran, Florian, Voß, Mathias, Zeuner, Rainald, Morrison, Peter J., Bacher, Petra, Fickenscher, Helmut, Gerdes, Sascha, Peipp, Matthias, Schreiber, Stefan, Krumbholz, Andi, Hoyer, Bimba Franziska
Publicado 2022