Concentration‐QTc Modeling of Ozanimod’s Major Active Metabolites in Adult Healthy Subjects

por Briggs, Emily, Chapel, Sunny, Zhang, Peijin, Palmisano, Maria, Tran, Jonathan Q.
Publicado 2021

Pharmacokinetics of daclizumab high-yield process with repeated administration of the clinical subcutaneous regimen in patients with relapsing-remitting multiple sclerosis

por Tran, Jonathan Q, Othman, Ahmed A, Mikulskis, Alvydas, Wolstencroft, Paul, Elkins, Jacob
Publicado 2016

Effects of High‐ and Low‐Fat Meals on the Pharmacokinetics of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator

por Tran, Jonathan Q., Hartung, Jeffrey P., Tompkins, Cindy‐Ann, Frohna, Paul A.
Publicado 2017

Effect of the sphingosine-1-phosphate receptor modulator ozanimod on leukocyte subtypes in relapsing MS

por Harris, Sarah, Tran, Jonathan Q., Southworth, Harry, Spencer, Collin M., Cree, Bruce A.C., Zamvil, Scott S.
Publicado 2020

Multiple-Dose Pharmacokinetics of Ozanimod and its Major Active Metabolites and the Pharmacodynamic and Pharmacokinetic Interactions with Pseudoephedrine, a Sympathomimetic Agent,...

por Tran, Jonathan Q., Zhang, Peijin, Walker, Susan, Ghosh, Atalanta, Syto, Mary, Wang, Xiaomin, Harris, Sarah, Palmisano, Maria
Publicado 2020

Cardiac Safety of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator: Results of a Thorough QT/QTc Study

por Tran, Jonathan Q., Hartung, Jeffrey P., Olson, Allan D., Mendzelevski, Boaz, Timony, Gregg A., Boehm, Marcus F., Peach, Robert J., Gujrathi, Sheila, Frohna, Paul A.
Publicado 2017

Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033

por Tran, Jonathan Q., Rana, Jitesh, Barkhof, Frederik, Melamed, Isaac, Gevorkyan, Hakop, Wattjes, Mike P., de Jong, Remko, Brosofsky, Kristin, Ray, Soma, Xu, Lei, Zhao, Jim, Parr, Edward, Cadavid, Diego
Publicado 2014

Results From the First‐in‐Human Study With Ozanimod, a Novel, Selective Sphingosine‐1‐Phosphate Receptor Modulator

por Tran, Jonathan Q., Hartung, Jeffrey P., Peach, Robert J., Boehm, Marcus F., Rosen, Hugh, Smith, Heather, Brooks, Jennifer L., Timony, Gregg A., Olson, Allan D., Gujrathi, Sheila, Frohna, Paul A.
Publicado 2017