Protocol for Efficient CRISPR/Cas9/AAV-Mediated Homologous Recombination in Mouse Hematopoietic Stem and Progenitor Cells

por Tran, Ngoc Tung, Trombke, Janine, Rajewsky, Klaus, Chu, Van Trung
Publicado 2020

Application of a Spacer-nick Gene-targeting Approach to Repair Disease-causing Mutations with Increased Safety

por Tran, Ngoc Tung, Lebedin, Mikhail, Danner, Eric, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2023

Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors

por Tran, Ngoc-Tung, Bashir, Sanum, Li, Xun, Rossius, Jana, Chu, Van Trung, Rajewsky, Klaus, Kühn, Ralf
Publicado 2019

Corrigendum: Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors

por Tran, Ngoc-Tung, Bashir, Sanum, Li, Xun, Rossius, Jana, Chu, Van Trung, Rajewsky, Klaus, Kühn, Ralf
Publicado 2020

Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells

por Tran, Ngoc Tung, Sommermann, Thomas, Graf, Robin, Trombke, Janine, Pempe, Jenniffer, Petsch, Kerstin, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2019

CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia

por Tran, Ngoc Tung, Graf, Robin, Wulf-Goldenberg, Annika, Stecklum, Maria, Strauß, Gabriele, Kühn, Ralf, Kocks, Christine, Rajewsky, Klaus, Chu, Van Trung
Publicado 2020

Splicing factor SF3B1(K700E) mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

por Jin, Shuiling, Su, Hairui, Tran, Ngoc-Tung, Song, Jing, Lu, Sydney S., Li, Ying, Huang, Suming, Abdel-Wahab, Omar, Liu, Yanyan, Zhao, Xinyang
Publicado 2017

Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells

por Tran, Ngoc Tung, Danner, Eric, Li, Xun, Graf, Robin, Lebedin, Mikhail, de la Rosa, Kathrin, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2022

Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma

por Nguyen, Hong Phuong, Le, Anh Quynh, Liu, Enze, Cesarano, Annamaria, DiMeo, Francesco, Perna, Fabiana, Kapur, Reuben, Walker, Brian A., Tran, Ngoc Tung
Publicado 2023

Corrigendum: Protein arginine methyltransferase 1 is a therapeutic vulnerability in multiple myeloma

por Nguyen, Hong Phuong, Le, Anh Quynh, Liu, Enze, Cesarano, Annamaria, DiMeo, Francesco, Perna, Fabiana, Kapur, Reuben, Walker, Brian A., Tran, Ngoc Tung
Publicado 2023

Efficient and Precise CRISPR/Cas9-Mediated MECP2 Modifications in Human-Induced Pluripotent Stem Cells

por Le, Thi Thanh Huong, Tran, Ngoc Tung, Dao, Thi Mai Lan, Nguyen, Dinh Dung, Do, Huy Duong, Ha, Thi Lien, Kühn, Ralf, Nguyen, Thanh Liem, Rajewsky, Klaus, Chu, Van Trung
Publicado 2019

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing

por Zhang, Li, Tran, Ngoc-Tung, Su, Hairui, Wang, Rui, Lu, Yuheng, Tang, Haiping, Aoyagi, Sayura, Guo, Ailan, Khodadadi-Jamayran, Alireza, Zhou, Dewang, Qian, Kun, Hricik, Todd, Côté, Jocelyn, Han, Xiaosi, Zhou, Wenping, Laha, Suparna, Abdel-Wahab, Omar, Levine, Ross L, Raffel, Glen, Liu, Yanyan, Chen, Dongquan, Li, Haitao, Townes, Tim, Wang, Hengbin, Deng, Haiteng, Zheng, Y George, Leslie, Christina, Luo, Minkui, Zhao, Xinyang
Publicado 2015

Methylation of dual-specificity phosphatase 4 controls cell differentiation

por Su, Hairui, Jiang, Ming, Senevirathne, Chamara, Aluri, Srinivas, Zhang, Tuo, Guo, Han, Xavier-Ferrucio, Juliana, Jin, Shuiling, Tran, Ngoc-Tung, Liu, Szu-Mam, Sun, Chiao-Wang, Zhu, Yongxia, Zhao, Qing, Chen, Yuling, Cable, LouAnn, Shen, Yudao, Liu, Jing, Qu, Cheng-Kui, Han, Xiaosi, Klug, Christopher A., Bhatia, Ravi, Chen, Yabing, Nimer, Stephen D., Zheng, Y. George, Iancu-Rubin, Camelia, Jin, Jian, Deng, Haiteng, Krause, Diane S., Xiang, Jenny, Verma, Amit, Luo, Minkui, Zhao, Xinyang
Publicado 2021