Kendomycin Cytotoxicity against Bacterial, Fungal, and Mammalian Cells Is Due to Cation Chelation

por Tranter, Dale, Filipuzzi, Ireos, Lochmann, Thomas, Knapp, Britta, Kellosalo, Juho, Estoppey, David, Pistorius, Dominik, Meissner, Axel, Paavilainen, Ville O., Hoepfner, Dominic
Publicado 2020

Snapshots of actin and tubulin folding inside the TRiC chaperonin

por Kelly, John J., Tranter, Dale, Pardon, Els, Chi, Gamma, Kramer, Holger, Happonen, Lotta, Knee, Kelly M., Janz, Jay M., Steyaert, Jan, Bulawa, Christine, Paavilainen, Ville O., Huiskonen, Juha T., Yue, Wyatt W.
Publicado 2022

Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins

por Tranter, Dale, Paatero, Anja O., Kawaguchi, Shinsaku, Kazemi, Soheila, Serrill, Jeffrey D., Kellosalo, Juho, Vogel, Walter K., Richter, Uwe, Mattos, Daphne R., Wan, Xuemei, Thornburg, Christopher C., Oishi, Shinya, McPhail, Kerry L., Ishmael, Jane E., Paavilainen, Ville O.
Publicado 2020

Signal peptide mimicry primes Sec61 for client-selective inhibition

por Rehan, Shahid, Tranter, Dale, Sharp, Phillip P., Craven, Gregory B., Lowe, Eric, Anderl, Janet L., Muchamuel, Tony, Abrishami, Vahid, Kuivanen, Suvi, Wenzell, Nicole A., Jennings, Andy, Kalyanaraman, Chakrapani, Strandin, Tomas, Javanainen, Matti, Vapalahti, Olli, Jacobson, Matthew P., McMinn, Dustin, Kirk, Christopher J., Huiskonen, Juha T., Taunton, Jack, Paavilainen, Ville O.
Publicado 2023

Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation

por Zong, Guanghui, Hu, Zhijian, O’Keefe, Sarah, Tranter, Dale, Iannotti, Michael J., Baron, Ludivine, Hall, Belinda, Corfield, Katherine, Paatero, Anja O., Henderson, Mark J., Roboti, Peristera, Zhou, Jianhong, Sun, Xianwei, Govindarajan, Mugunthan, Rohde, Jason M., Blanchard, Nicolas, Simmonds, Rachel, Inglese, James, Du, Yuchun, Demangel, Caroline, High, Stephen, Paavilainen, Ville O., Shi, Wei Q.
Publicado 2019