Insights from mathematical modeling for convection-enhanced intraputamenal delivery of GDNF

por Belova, Elena, Shaffer, Christopher L., Trapa, Patrick E.
Publicado 2017

Optimization of dose and route of administration of the P‐glycoprotein inhibitor, valspodar (PSC‐833) and the P‐glycoprotein and breast cancer resistance protein dual‐inhibitor, el...

por Rowbottom, Christopher, Pietrasiewics, Alicia, Tuczewycz, Taras, Grater, Richard, Qiu, Daniel, Kapadnis, Sudarshan, Trapa, Patrick
Publicado 2021

Development of a one-step RT-ddPCR method to determine the expression and potency of AAV vectors

por Clarner, Pete, Lau, Shukkwan K., Chowdhury, Twinkle, Guilmette, Edward, Trapa, Patrick, Lo, Shih-Ching, Shen, Shen
Publicado 2021

Target occupancy study and whole-body dosimetry with a MAGL PET ligand [(11)C]PF-06809247 in non-human primates

por Arakawa, Ryosuke, Takano, Akihiro, Nag, Sangram, Jia, Zhisheng, Amini, Nahid, Maresca, Kevin P., Zhang, Lei, Keliher, Edmund J., Butler, Christopher R., Piro, Justin R., Samad, Tarek A., Smith, Deborah, Nason, Deane, O’Neil, Steve, Trapa, Patrick, Fonseca, Kari R., Litchfield, John, McCarthy, Timothy, Carson, Richard E., Halldin, Christer
Publicado 2022

Next‐generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells...

por Bame, Eris, Tang, Hao, Burns, Jeremy C, Arefayene, Million, Michelsen, Klaus, Ma, Bin, Marx, Isaac, Prince, Robin, Roach, Allie M, Poreci, Urjana, Donaldson, Douglas, Cullen, Patrick, Casey, Fergal, Zhu, Jing, Carlile, Thomas M, Sangurdekar, Dipen, Zhang, Baohong, Trapa, Patrick, Santoro, Joseph, Muragan, Param, Pellerin, Alex, Rubino, Stephen, Gianni, Davide, Bajrami, Bekim, Peng, Xiaomei, Coppell, Alex, Riester, Katherine, Belachew, Shibeshih, Mehta, Devangi, Palte, Mike, Hopkins, Brian T, Scaramozza, Matthew, Franchimont, Nathalie, Mingueneau, Michael
Publicado 2021