Computational analyses of mechanism of action (MoA): data, methods and integration

por Trapotsi, Maria-Anna, Hosseini-Gerami, Layla, Bender, Andreas
Publicado 2021

Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection

por Seal, Srijit, Carreras-Puigvert, Jordi, Trapotsi, Maria-Anna, Yang, Hongbin, Spjuth, Ola, Bender, Andreas
Publicado 2022

Merging bioactivity predictions from cell morphology and chemical fingerprint models using similarity to training data

por Seal, Srijit, Yang, Hongbin, Trapotsi, Maria-Anna, Singh, Satvik, Carreras-Puigvert, Jordi, Spjuth, Ola, Bender, Andreas
Publicado 2023

Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

por van Lopik, Jasper, Alizada, Azad, Trapotsi, Maria-Anna, Hannon, Gregory J., Bornelöv, Susanne, Czech Nicholson, Benjamin
Publicado 2023

Probabilistic Random Forest improves bioactivity predictions close to the classification threshold by taking into account experimental uncertainty

por Mervin, Lewis H., Trapotsi, Maria-Anna, Afzal, Avid M., Barrett, Ian P., Bender, Andreas, Engkvist, Ola
Publicado 2021

In silico prediction and biological assessment of novel angiogenesis modulators from traditional Chinese medicine

por Zhu, Yingli, Yang, Hongbin, Han, Liwen, Mervin, Lewis H., Hosseini-Gerami, Layla, Li, Peihai, Wright, Peter, Trapotsi, Maria-Anna, Liu, Kechun, Fan, Tai-Ping, Bender, Andreas
Publicado 2023

Cell Morphological Profiling Enables High-Throughput Screening for PROteolysis TArgeting Chimera (PROTAC) Phenotypic Signature

por Trapotsi, Maria-Anna, Mouchet, Elizabeth, Williams, Guy, Monteverde, Tiziana, Juhani, Karolina, Turkki, Riku, Miljković, Filip, Martinsson, Anton, Mervin, Lewis, Pryde, Kenneth R., Müllers, Erik, Barrett, Ian, Engkvist, Ola, Bender, Andreas, Moreau, Kevin
Publicado 2022