Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis

por Traxel, Sabrina, Lehmann, Julia, Richard, Stefanie, Sidorov, Semjon, Niggli, Felix, Berger, Christoph, Nadal, David, Bürgler, Simone
Publicado 2021

Epstein–Barr virus and malaria upregulate AID and APOBEC3 enzymes, but only AID seems to play a major mutagenic role in Burkitt lymphoma

por Summerauer, Andrea M., Jäggi, Vera, Ogwang, Rodney, Traxel, Sabrina, Colombo, Lorenzo, Amundsen, Eivind, Eyer, Tatjana, Subramanian, Bibin, Fehr, Jan, Mantel, Pierre‐Yves, Idro, Richard, Bürgler, Simone
Publicado 2022

CD4 + T cells are found within endemic Burkitt lymphoma and modulate Burkitt lymphoma precursor cell viability and expression of pathogenically relevant Epstein–Barr virus genes...

por Sidorov, Semjon, Fux, Lara, Steiner, Katja, Bounlom, Samyo, Traxel, Sabrina, Azzi, Tarik, Berisha, Arbeneshe, Berger, Christoph, Bernasconi, Michele, Niggli, Felix K., Perner, Yvonne, Pather, Sugeshnee, Kempf, Werner, Nadal, David, Bürgler, Simone
Publicado 2021