The Impact of “Omic” and Imaging Technologies on Assessing the Host Immune Response to Biodefence Agents

por Tree, Julia A., Flick-Smith, Helen, Elmore, Michael J., Rowland, Caroline A.
Publicado 2014

Vaccines and Therapies for Biodefence Agents

por Tree, Julia A., Williamson, E. Diane, Rowland, Caroline A., Pitt, Louise M.
Publicado 2015

Evidence for a Role for Interleukin-17, Th17 Cells and Iron Homeostasis in Protective Immunity against Tuberculosis in Cynomolgus Macaques

por Wareham, Alice S., Tree, Julia A., Marsh, Philip D., Butcher, Philip D., Dennis, Mike, Sharpe, Sally A.
Publicado 2014

Repeated high-dose (5 × 10(8) TCID(50)) toxicity study of a third generation smallpox vaccine (IMVAMUNE) in New Zealand white rabbits

por Tree, Julia A., Hall, Graham, Rees, Peter, Vipond, Julia, Funnell, Simon G. P., Roberts, Allen D.
Publicado 2016

Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)(2) fragments

por Findlay-Wilson, Stephen, Easterbrook, Linda, Smith, Sandra, Pope, Neville, Aldridge, Matthew, Humphries, Gareth, Schuhmann, Holger, Ngabo, Didier, Rayner, Emma, Otter, Ashley, Coleman, Thomas, Hicks, Bethany, Halkerston, Rachel, Apostolakis, Kostis, Taylor, Stephen, Fotheringham, Susan, Horton, Amanda, CanoCejas, Irene, Wand, Matthew, Tree, Julia A., Sutton, Mark, Graham, Victoria, Hewson, Roger, Dowall, Stuart
Publicado 2023

Publisher Correction: Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab′)(2) fragments

por Findlay‑Wilson, Stephen, Easterbrook, Linda, Smith, Sandra, Pope, Neville, Aldridge, Matthew, Humphries, Gareth, Schuhmann, Holger, Ngabo, Didier, Rayner, Emma, Otter, Ashley, Coleman, Thomas, Hicks, Bethany, Halkerston, Rachel, Apostolakis, Kostis, Taylor, Stephen, Fotheringham, Susan, Horton, Amanda, CanoCejas, Irene, Wand, Matthew, Tree, Julia A., Sutton, Mark, Graham, Victoria, Hewson, Roger, Dowall, Stuart
Publicado 2023

Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations

por Tree, Julia A., Turnbull, Jeremy E., Buttigieg, Karen R., Elmore, Michael J., Coombes, Naomi, Hogwood, John, Mycroft‐West, Courtney J., Lima, Marcelo A., Skidmore, Mark A., Karlsson, Richard, Chen, Yen‐Hsi, Yang, Zhang, Spalluto, Cosma Mirella, Staples, Karl J., Yates, Edwin A., Gray, Elaine, Singh, Dave, Wilkinson, Tom, Page, Clive P., Carroll, Miles W.
Publicado 2020

A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction

por Ejemel, Monir, Li, Qi, Hou, Shurong, Schiller, Zachary A., Tree, Julia A., Wallace, Aaron, Amcheslavsky, Alla, Kurt Yilmaz, Nese, Buttigieg, Karen R., Elmore, Michael J., Godwin, Kerry, Coombes, Naomi, Toomey, Jacqueline R., Schneider, Ryan, Ramchetty, Anudeep S., Close, Brianna J., Chen, Da-Yuan, Conway, Hasahn L., Saeed, Mohsan, Ganesa, Chandrashekar, Carroll, Miles W., Cavacini, Lisa A., Klempner, Mark S., Schiffer, Celia A., Wang, Yang
Publicado 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

por Huo, Jiandong, Zhao, Yuguang, Ren, Jingshan, Zhou, Daming, Duyvesteyn, Helen M.E., Ginn, Helen M., Carrique, Loic, Malinauskas, Tomas, Ruza, Reinis R., Shah, Pranav N.M., Tan, Tiong Kit, Rijal, Pramila, Coombes, Naomi, Bewley, Kevin R., Tree, Julia A., Radecke, Julika, Paterson, Neil G., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Carroll, Miles, Townsend, Alain, Fry, Elizabeth E., Owens, Raymond J., Stuart, David I.
Publicado 2020

The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

por Goldswain, Hannah, Dong, Xiaofeng, Penrice-Randal, Rebekah, Alruwaili, Muhannad, Shawli, Ghada T., Prince, Tessa, Williamson, Maia Kavanagh, Raghwani, Jayna, Randle, Nadine, Jones, Benjamin, Donovan-Banfield, I’ah, Salguero, Francisco J., Tree, Julia A., Hall, Yper, Hartley, Catherine, Erdmann, Maximilian, Bazire, James, Jearanaiwitayakul, Tuksin, Semple, Malcolm G., Openshaw, Peter J. M., Baillie, J. Kenneth, Emmett, Stevan R., Digard, Paul, Matthews, David A., Turtle, Lance, Darby, Alistair C., Davidson, Andrew D., Carroll, Miles W., Hiscox, Julian A.
Publicado 2023

Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2

por Huang, Kuan-Ying A., Zhou, Daming, Tan, Tiong Kit, Chen, Charles, Duyvesteyn, Helen M. E., Zhao, Yuguang, Ginn, Helen M., Qin, Ling, Rijal, Pramila, Schimanski, Lisa, Donat, Robert, Harding, Adam, Gilbert-Jaramillo, Javier, James, William, Tree, Julia A., Buttigieg, Karen, Carroll, Miles, Charlton, Sue, Lien, Chia-En, Lin, Meei-Yun, Chen, Cheng-Pin, Cheng, Shu-Hsing, Chen, Xiaorui, Lin, Tzou-Yien, Fry, Elizabeth E., Ren, Jingshan, Ma, Che, Townsend, Alain R., Stuart, David I.
Publicado 2022

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

por Huo, Jiandong, Mikolajek, Halina, Le Bas, Audrey, Clark, Jordan J., Sharma, Parul, Kipar, Anja, Dormon, Joshua, Norman, Chelsea, Weckener, Miriam, Clare, Daniel K., Harrison, Peter J., Tree, Julia A., Buttigieg, Karen R., Salguero, Francisco J., Watson, Robert, Knott, Daniel, Carnell, Oliver, Ngabo, Didier, Elmore, Michael J., Fotheringham, Susan, Harding, Adam, Moynié, Lucile, Ward, Philip N., Dumoux, Maud, Prince, Tessa, Hall, Yper, Hiscox, Julian A., Owen, Andrew, James, William, Carroll, Miles W., Stewart, James P., Naismith, James H., Owens, Raymond J.
Publicado 2021

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

por Huo, Jiangdong, Le Bas, Audrey, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.
Publicado 2020

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

por Huo, Jiandong, Bas, Audrey Le, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.
Publicado 2021

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction

por Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T., Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Wand, Matthew, Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D. J., Chhabra, Mohit, Young, Paul R., Rawle, Daniel J., Lima, Marcelo A., Yates, Edwin A., Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Nguyen, Dung, Laidlaw, Stephen, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M. A., Watterson, Daniel, Khromykh, Alexander A., Suhrbier, Andreas, Carroll, Miles W., Trybala, Edward, Bergström, Tomas, Ferro, Vito, Skidmore, Mark A., Turnbull, Jeremy E.
Publicado 2022

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

por Tan, Tiong Kit, Rijal, Pramila, Rahikainen, Rolle, Keeble, Anthony H., Schimanski, Lisa, Hussain, Saira, Harvey, Ruth, Hayes, Jack W. P., Edwards, Jane C., McLean, Rebecca K., Martini, Veronica, Pedrera, Miriam, Thakur, Nazia, Conceicao, Carina, Dietrich, Isabelle, Shelton, Holly, Ludi, Anna, Wilsden, Ginette, Browning, Clare, Zagrajek, Adrian K., Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Hollinghurst, Philippa, Tully, Matthew, Moffat, Katy, Chiu, Chris, Waters, Ryan, Gray, Ashley, Azhar, Mehreen, Mioulet, Valerie, Newman, Joseph, Asfor, Amin S., Burman, Alison, Crossley, Sylvia, Hammond, John A., Tchilian, Elma, Charleston, Bryan, Bailey, Dalan, Tuthill, Tobias J., Graham, Simon P., Duyvesteyn, Helen M. E., Malinauskas, Tomas, Huo, Jiandong, Tree, Julia A., Buttigieg, Karen R., Owens, Raymond J., Carroll, Miles W., Daniels, Rodney S., McCauley, John W., Stuart, David I., Huang, Kuan-Ying A., Howarth, Mark, Townsend, Alain R.
Publicado 2021

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

por Ryan, Kathryn A., Bewley, Kevin R., Fotheringham, Susan A., Slack, Gillian S., Brown, Phillip, Hall, Yper, Wand, Nadina I., Marriott, Anthony C., Cavell, Breeze E., Tree, Julia A., Allen, Lauren, Aram, Marilyn J., Bean, Thomas J., Brunt, Emily, Buttigieg, Karen R., Carter, Daniel P., Cobb, Rebecca, Coombes, Naomi S., Findlay-Wilson, Steve J., Godwin, Kerry J., Gooch, Karen E., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas H., Humphries, Holly E., Hunter, Laura, Ho, Catherine M. K., Kennard, Chelsea L., Leung, Stephanie, Longet, Stephanie, Ngabo, Didier, Osman, Karen L., Paterson, Jemma, Penn, Elizabeth J., Pullan, Steven T., Rayner, Emma, Skinner, Oliver, Steeds, Kimberley, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Turner, Carrie, Watson, Robert J., Wiblin, Nathan R., Charlton, Sue, Hallis, Bassam, Hiscox, Julian A., Funnell, Simon, Dennis, Mike J., Whittaker, Catherine J., Catton, Michael G., Druce, Julian, Salguero, Francisco J., Carroll, Miles W.
Publicado 2021

Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

por Salguero, Francisco J., White, Andrew D., Slack, Gillian S., Fotheringham, Susan A., Bewley, Kevin R., Gooch, Karen E., Longet, Stephanie, Humphries, Holly E., Watson, Robert J., Hunter, Laura, Ryan, Kathryn A., Hall, Yper, Sibley, Laura, Sarfas, Charlotte, Allen, Lauren, Aram, Marilyn, Brunt, Emily, Brown, Phillip, Buttigieg, Karen R., Cavell, Breeze E., Cobb, Rebecca, Coombes, Naomi S., Darby, Alistair, Daykin-Pont, Owen, Elmore, Michael J., Garcia-Dorival, Isabel, Gkolfinos, Konstantinos, Godwin, Kerry J., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas, Ho, Catherine M. K., Kennard, Chelsea L., Knott, Daniel, Leung, Stephanie, Lucas, Vanessa, Mabbutt, Adam, Morrison, Alexandra L., Nelson, Charlotte, Ngabo, Didier, Paterson, Jemma, Penn, Elizabeth J., Pullan, Steve, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Tree, Julia A., Turner, Carrie, Vamos, Edith, Wand, Nadina, Wiblin, Nathan R., Charlton, Sue, Dong, Xiaofeng, Hallis, Bassam, Pearson, Geoffrey, Rayner, Emma L., Nicholson, Andrew G., Funnell, Simon G., Hiscox, Julian A., Dennis, Mike J., Gleeson, Fergus V., Sharpe, Sally, Carroll, Miles W.
Publicado 2021