IL-2-based approaches to Treg enhancement

por Harris, Ffion, Berdugo, Yoana Arroyo, Tree, Timothy
Publicado 2022

Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?

por Hull, Caroline M., Peakman, Mark, Tree, Timothy I. M.
Publicado 2017

The Impact of Immune-Modifying Treatments for Skin Diseases on the Immune Response to COVID-19 Vaccines: a Narrative Review

por Liew, Su-Yi, Tree, Timothy, Smith, Catherine H., Mahil, Satveer K.
Publicado 2022

Monitoring islet specific immune responses in type 1 diabetes clinical immunotherapy trials

por Arif, Sefina, Domingo-Vila, Clara, Pollock, Emily, Christakou, Eleni, Williams, Evangelia, Tree, Timothy I. M.
Publicado 2023

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

por Tree, Timothy I.M., Lawson, Jennifer, Edwards, Hannah, Skowera, Ania, Arif, Sefina, Roep, Bart O., Peakman, Mark
Publicado 2010

Senescent-like Blood Lymphocytes and Disease Progression in Amyotrophic Lateral Sclerosis

por Yildiz, Ozlem, Schroth, Johannes, Tree, Timothy, Turner, Martin R., Shaw, Pamela J., Henson, Sian M., Malaspina, Andrea
Publicado 2022

The Expression of Active CD11b Monocytes in Blood and Disease Progression in Amyotrophic Lateral Sclerosis

por Yildiz, Ozlem, Schroth, Johannes, Lombardi, Vittoria, Pucino, Valentina, Bobeva, Yoana, Yip, Ping Kei, Schmierer, Klaus, Mauro, Claudio, Tree, Timothy, Henson, Sian Mari, Malaspina, Andrea
Publicado 2022

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes

por Dunger, David B., Bruggraber, Sylvaine F. A., Mander, Adrian P., Marcovecchio, M. Loredana, Tree, Timothy, Chmura, Piotr Jaroslaw, Knip, Mikael, Schulte, Anke M., Mathieu, Chantal
Publicado 2022

Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner

por Carty, Fiona, Corbett, Jennifer M., Cunha, João Paulo M. C. M., Reading, James L., Tree, Timothy I. M., Ting, Anthony E., Stubblefield, Samantha R., English, Karen
Publicado 2018

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects

por Arif, Sefina, Pujol-Autonell, Irma, Kamra, Yogesh, Williams, Evangelia, Yusuf, Norkhairin, Domingo-Vila, Clara, Shahrabi, Yasaman, Pollock, Emily, Khatri, Leena, Peakman, Mark, Tree, Timothy, Lorenc, Anna
Publicado 2021

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

por Allen, Jennifer S., Pang, Karl, Skowera, Ania, Ellis, Richard, Rackham, Chloe, Lozanoska-Ochser, Biliana, Tree, Timothy, Leslie, R. David G., Tremble, Jennifer M., Dayan, Colin M., Peakman, Mark
Publicado 2009

GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells

por Arif, Sefina, Gomez-Tourino, Iria, Kamra, Yogesh, Pujol-Autonell, Irma, Hanton, Emily, Tree, Timothy, Melandri, Daisy, Hull, Caroline, Wherrett, Diane K., Beam, Craig, Roep, Bart O., Lorenc, Anna, Peakman, Mark
Publicado 2020

Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes

por Liu, Yuk-Fun, Powrie, Jake, Arif, Sefina, Yang, Jennie H.M., Williams, Evangelia, Khatri, Leena, Joshi, Mamta, Lhuillier, Loic, Fountoulakis, Nikolaos, Smith, Emma, Beam, Craig, Lorenc, Anna, Peakman, Mark, Tree, Timothy
Publicado 2022

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis

por Lu, Ching-Hua, Allen, Kezia, Oei, Felicia, Leoni, Emanuela, Kuhle, Jens, Tree, Timothy, Fratta, Pietro, Sharma, Nikhil, Sidle, Katie, Howard, Robin, Orrell, Richard, Fish, Mark, Greensmith, Linda, Pearce, Neil, Gallo, Valentina, Malaspina, Andrea
Publicado 2016

Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects via Adult Progenitor Cell Co-Culture

por Reading, James L., Roobrouck, Valerie D., Hull, Caroline M., Becker, Pablo Daniel, Beyens, Jelle, Valentin-Torres, Alice, Boardman, Dominic, Lamperti, Estefania Nova, Stubblefield, Samantha, Lombardi, Giovanna, Deans, Robert, Ting, Anthony E., Tree, Timothy
Publicado 2021

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

por Arif, Sefina, Moore, Fabrice, Marks, Katherine, Bouckenooghe, Thomas, Dayan, Colin M., Planas, Raquel, Vives-Pi, Marta, Powrie, Jake, Tree, Timothy, Marchetti, Piero, Huang, Guo Cai, Gurzov, Esteban N., Pujol-Borrell, Ricardo, Eizirik, Decio L., Peakman, Mark
Publicado 2011

Concordance of B‐ and T‐cell responses to SARS‐CoV‐2 infection, irrespective of symptoms suggestive of COVID‐19

por Österdahl, Marc F., Christakou, Eleni, Hart, Deborah, Harris, Ffion, Shahrabi, Yasaman, Pollock, Emily, Wadud, Muntaha, Spector, Tim D., Brown, Matthew A., Seow, Jeffrey, Malim, Michael H., Steves, Claire J., Doores, Katie J., Duncan, Emma L., Tree, Timothy
Publicado 2022

Type 1 diabetes can present before the age of 6 months and is characterised by autoimmunity and rapid loss of beta cells

por Johnson, Matthew B., Patel, Kashyap A., De Franco, Elisa, Hagopian, William, Killian, Michael, McDonald, Timothy J., Tree, Timothy I. M., Domingo-Vila, Clara, Hudson, Michelle, Hammersley, Suzanne, Dobbs, Rebecca, Ellard, Sian, Flanagan, Sarah E., Hattersley, Andrew T., Oram, Richard A.
Publicado 2020

Low-dose IL-2 reduces IL-21(+) T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes

por Zhang, Jia-Yuan, Hamey, Fiona, Trzupek, Dominik, Mickunas, Marius, Lee, Mercede, Godfrey, Leila, Yang, Jennie H. M., Pekalski, Marcin L., Kennet, Jane, Waldron-Lynch, Frank, Evans, Mark L., Tree, Timothy I. M., Wicker, Linda S., Todd, John A., Ferreira, Ricardo C.
Publicado 2022

Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer

por McKenzie, Duncan R., Graham, Rosalind, Lechmere, Thomas, Domingo-Vila, Clara, Alaguthurai, Thanussuyah, Arman, Celeste, Pollock, Emily, Gousis, Charalampos, Kakkassery, Helen, Carpenter, Esme, Kurshan, Ashwini, Vidler, Jennifer, Kulasekararaj, Austin, Patten, Piers, North, Bernard V., Tree, Timothy, Doores, Katie J., Hayday, Adrian C., Irshad, Sheeba
Publicado 2022