FluxFix: automatic isotopologue normalization for metabolic tracer analysis

por Trefely, Sophie, Ashwell, Peter, Snyder, Nathaniel W.
Publicado 2016

Compartmentalised acyl-CoA metabolism and roles in chromatin regulation

por Trefely, Sophie, Lovell, Claudia D., Snyder, Nathaniel W., Wellen, Kathryn E.
Publicado 2020

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated ‘don’t eat me signal’.

por Liu, Mingen, O’Connor, Roddy S., Trefely, Sophie, Graham, Kathleen, Snyder, Nathaniel W., Beatty, Gregory L
Publicado 2019

Dynamic protein deacetylation is a limited carbon source for acetyl-CoA–dependent metabolism

por Soaita, Ioana, Megill, Emily, Kantner, Daniel, Chatoff, Adam, Cheong, Yuen Jian, Clarke, Philippa, Arany, Zoltan, Snyder, Nathaniel W., Wellen, Kathryn E., Trefely, Sophie
Publicado 2023

Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism

por Trefely, Sophie, Liu, Joyce, Huber, Katharina, Doan, Mary T., Jiang, Helen, Singh, Jay, von Krusenstiern, Eliana, Bostwick, Anna, Xu, Peining, Bogner-Strauss, Juliane G., Wellen, Kathryn E., Snyder, Nathaniel W.
Publicado 2019

Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues

por Varner, Erika L., Trefely, Sophie, Bartee, David, von Krusenstiern, Eliana, Izzo, Luke, Bekeova, Carmen, O'Connor, Roddy S., Seifert, Erin L., Wellen, Kathryn E., Meier, Jordan L., Snyder, Nathaniel W.
Publicado 2020

Glutamine deprivation triggers NAGK-dependent hexosamine salvage

por Campbell, Sydney, Mesaros, Clementina, Izzo, Luke, Affronti, Hayley, Noji, Michael, Schaffer, Bethany E, Tsang, Tiffany, Sun, Kathryn, Trefely, Sophie, Kruijning, Salisa, Blenis, John, Blair, Ian A, Wellen, Kathryn E
Publicado 2021

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis

por Martinez Calejman, C., Trefely, S., Entwisle, S. W., Luciano, A., Jung, S. M., Hsiao, W., Torres, A., Hung, C. M., Li, H., Snyder, N. W., Villén, J., Wellen, K. E., Guertin, D. A.
Publicado 2020

Author Correction: mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis

por Calejman, C. Martinez, Trefely, S., Entwisle, S. W., Luciano, A., Jung, S. M., Hsiao, W., Torres, A., Hung, C. M., Li, H., Snyder, N. W., Villén, J., Wellen, K. E., Guertin, D. A.
Publicado 2020

Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

por Fernandez, Sully, Viola, John M., Torres, AnnMarie, Wallace, Martina, Trefely, Sophie, Zhao, Steven, Affronti, Hayley C., Gengatharan, Jivani M., Guertin, David A., Snyder, Nathaniel W., Metallo, Christian M., Wellen, Kathryn E.
Publicado 2019

Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism

por Shah, Supriya, Carriveau, Whitney J., Li, Jinyang, Campbell, Sydney L., Kopinski, Piotr K., Lim, Hee-Woong, Daurio, Natalie, Trefely, Sophie, Won, Kyoung-Jae, Wallace, Douglas C., Koumenis, Constantinos, Mancuso, Anthony, Wellen, Kathryn E.
Publicado 2016

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations

por O’Connor, Roddy S., Guo, Lili, Ghassemi, Saba, Snyder, Nathaniel W., Worth, Andrew J., Weng, Liwei, Kam, Yoonseok, Philipson, Benjamin, Trefely, Sophie, Nunez-Cruz, Selene, Blair, Ian A., June, Carl H., Milone, Michael C.
Publicado 2018

CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production

por Garcia-Canaveras, Juan C., Heo, David, Trefely, Sophie, Leferovich, John, Xu, Chong, Philipson, Benjamin I., Ghassemi, Saba, Milone, Michael C., Moon, Edmund K., Snyder, Nathaniel W., June, Carl H., Rabinowitz, Joshua D., O’Connor, Roddy S.
Publicado 2021

Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis

por Izzo, Luke T., Trefely, Sophie, Demetriadou, Christina, Drummond, Jack M., Mizukami, Takuya, Kuprasertkul, Nina, Farria, Aimee T., Nguyen, Phuong T. T., Murali, Nivitha, Reich, Lauren, Kantner, Daniel S., Shaffer, Joshua, Affronti, Hayley, Carrer, Alessandro, Andrews, Andrew, Capell, Brian C., Snyder, Nathaniel W., Wellen, Kathryn E.
Publicado 2023

Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca(2+)–NFAT signaling

por Lee, Joyce V., Berry, Corbett T., Kim, Karla, Sen, Payel, Kim, Taehyong, Carrer, Alessandro, Trefely, Sophie, Zhao, Steven, Fernandez, Sully, Barney, Lauren E., Schwartz, Alyssa D., Peyton, Shelly R., Snyder, Nathaniel W., Berger, Shelley L., Freedman, Bruce D., Wellen, Kathryn E.
Publicado 2018

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

por Zhao, Steven, Jang, Cholsoon, Liu, Joyce, Uehara, Kahealani, Gilbert, Michael, Izzo, Luke, Zeng, Xianfeng, Trefely, Sophie, Fernandez, Sully, Carrer, Alessandro, Miller, Katelyn D., Schug, Zachary T., Snyder, Nathaniel W., Gade, Terence P., Titchenell, Paul M., Rabinowitz, Joshua D., Wellen, Kathryn E.
Publicado 2020

Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

por Doan, Mary T., Neinast, Michael D., Varner, Erika L., Bedi, Kenneth C., Bartee, David, Jiang, Helen, Trefely, Sophie, Xu, Peining, Singh, Jay P., Jang, Cholsoon, Rame, J. Eduardo, Brady, Donita C., Meier, Jordan L., Marguiles, Kenneth B., Arany, Zoltan, Snyder, Nathaniel W.
Publicado 2022

N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes

por Huber, Katharina, Hofer, Dina C., Trefely, Sophie, Pelzmann, Helmut J., Madreiter-Sokolowski, Corina, Duta-Mare, Madalina, Schlager, Stefanie, Trausinger, Gert, Stryeck, Sarah, Graier, Wolfgang F., Kolb, Dagmar, Magnes, Christoph, Snyder, Nathaniel W., Prokesch, Andreas, Kratky, Dagmar, Madl, Tobias, Wellen, Kathryn E., Bogner-Strauss, Juliane G.
Publicado 2018

Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

por Kopinski, Piotr K., Janssen, Kevin A., Schaefer, Patrick M., Trefely, Sophie, Perry, Caroline E., Potluri, Prasanth, Tintos-Hernandez, Jesus A., Singh, Larry N., Karch, Kelly R., Campbell, Sydney L., Doan, Mary T., Jiang, Helen, Nissim, Itzhak, Nakamaru-Ogiso, Eiko, Wellen, Kathryn E., Snyder, Nathaniel W., Garcia, Benjamin A., Wallace, Douglas C.
Publicado 2019