Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility

por Tremblay, Michel G., Moss, Tom
Publicado 2016

The cellular abundance of the essential transcription termination factor TTF-I regulates ribosome biogenesis and is determined by MDM2 ubiquitinylation

por Lessard, Frédéric, Stefanovsky, Victor, Tremblay, Michel G., Moss, Tom
Publicado 2012

The Short N-Terminal Repeats of Transcription Termination Factor 1 Contain Semi-Redundant Nucleolar Localization Signals and P19-ARF Tumor Suppressor Binding Sites

por Boutin, Joël, Lessard, Frédéric, Tremblay, Michel G., Moss, Tom
Publicado 2019

Loss of Extended Synaptotagmins ESyt2 and ESyt3 does not affect mouse development or viability, but in vitro cell migration and survival under stress are affected

por Herdman, Chelsea, Tremblay, Michel G, Mishra, Prakash K, Moss, Tom
Publicado 2014

The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling

por Jean, Steve, Tremblay, Michel G., Herdman, Chelsea, Guillou, François, Moss, Tom
Publicado 2012

A Deconvolution Protocol for ChIP-Seq Reveals Analogous Enhancer Structures on the Mouse and Human Ribosomal RNA Genes

por Mars, Jean-Clement, Sabourin-Felix, Marianne, Tremblay, Michel G., Moss, Tom
Publicado 2017

Depletion of the cisplatin targeted HMGB-box factor UBF selectively induces p53-independent apoptotic death in transformed cells

por Hamdane, Nourdine, Herdman, Chelsea, Mars, Jean-Clement, Stefanovsky, Victor, Tremblay, Michel G., Moss, Tom
Publicado 2015

Extended synaptotagmin interaction with the fibroblast growth factor receptor depends on receptor conformation, not catalytic activity.

por Tremblay, Michel G., Herdman, Chelsea, Guillou, François, Mishra, Prakash K., Baril, Joëlle, Bellenfant, Sabrina, Moss, Tom
Publicado 2016

The chemotherapeutic agent CX-5461 irreversibly blocks RNA polymerase I initiation and promoter release to cause nucleolar disruption, DNA damage and cell inviability

por Mars, Jean-Clément, Tremblay, Michel G, Valere, Mélissa, Sibai, Dany S, Sabourin-Felix, Marianne, Lessard, Frédéric, Moss, Tom
Publicado 2020

Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

por Hamdane, Nourdine, Stefanovsky, Victor Y., Tremblay, Michel G., Németh, Attila, Paquet, Eric, Lessard, Frédéric, Sanij, Elaine, Hannan, Ross, Moss, Tom
Publicado 2014

A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription

por Herdman, Chelsea, Mars, Jean-Clement, Stefanovsky, Victor Y., Tremblay, Michel G., Sabourin-Felix, Marianne, Lindsay, Helen, Robinson, Mark D., Moss, Tom
Publicado 2017

Ribosomal DNA promoter recognition is determined in vivo by cooperation between UBTF1 and SL1 and is compromised in the UBTF-E210K neuroregression syndrome

por Tremblay, Michel G., Sibai, Dany S., Valère, Melissa, Mars, Jean-Clément, Lessard, Frédéric, Hori, Roderick T., Khan, Mohammad Moshahid, Stefanovsky, Victor Y., LeDoux, Mark S., Moss, Tom
Publicado 2022

A recurrent de novo missense mutation in UBTF causes developmental neuroregression

por Toro, Camilo, Hori, Roderick T, Malicdan, May Christine V, Tifft, Cynthia J, Goldstein, Amy, Gahl, William A, Adams, David R, Fauni, Harper B, Wolfe, Lynne A, Xiao, Jianfeng, Khan, Mohammad M, Tian, Jun, Hope, Kevin A, Reiter, Lawrence T, Tremblay, Michel G, Moss, Tom, Franks, Alexis L, Balak, Chris, LeDoux, Mark S
Publicado 2018

A recurrent de novo missense mutation in UBTF causes developmental neuroregression

por Toro, Camilo, Hori, Roderick T, Malicdan, May Christine V, Tifft, Cynthia J, Goldstein, Amy, Gahl, William A, Adams, David R, Fauni, Harper B, Wolfe, Lynne A, Xiao, Jianfeng, Khan, Mohammad M, Tian, Jun, Hope, Kevin A, Reiter, Lawrence T, Tremblay, Michel G, Moss, Tom, Franks, Alexis L, Balak, Chris, LeDoux, Mark S
Publicado 2018