Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection

por Trempe, Jean-François, Fon, Edward A.
Publicado 2013

SUN-LB130 Identification of IGSF1 Ligands

por Smith, Courtney L, Bayne, Andrew N, Trempe, Jean-François, Bernard, Daniel J
Publicado 2020

The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria

por Maruszczak, Klaudia K., Jung, Martin, Rasool, Shafqat, Trempe, Jean-François, Rapaport, Doron
Publicado 2022

A new crystal form of Lys48-linked diubiquitin

por Trempe, Jean-François, Brown, Nicholas R., Noble, Martin E. M., Endicott, Jane A.
Publicado 2010

MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures

por Bayne, Andrew N., Dong, Jing, Amiri, Saeid, Farhan, Sali M. K., Trempe, Jean-François
Publicado 2023

Endogenous regulation of the Akt pathway by the aryl hydrocarbon receptor (AhR) in lung fibroblasts

por Shi, Fangyi, Aloufi, Noof, Traboulsi, Hussein, Trempe, Jean-François, Eidelman, David H., Baglole, Carolyn J.
Publicado 2021

Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation

por Tang, Matthew Y., Vranas, Marta, Krahn, Andrea I., Pundlik, Shayal, Trempe, Jean- François, Fon, Edward A.
Publicado 2017

Clinical and genetic analysis of ATP13A2 in hereditary spastic paraplegia expands the phenotype

por Estiar, Mehrdad A., Leveille, Etienne, Spiegelman, Dan, Dupre, Nicolas, Trempe, Jean-François, Rouleau, Guy A., Gan‐Or, Ziv
Publicado 2020

Structural Basis for Fe–S Cluster Assembly and tRNA Thiolation Mediated by IscS Protein–Protein Interactions

por Shi, Rong, Proteau, Ariane, Villarroya, Magda, Moukadiri, Ismaïl, Zhang, Linhua, Trempe, Jean-François, Matte, Allan, Armengod, M. Eugenia, Cygler, Miroslaw
Publicado 2010

A Ubl/ubiquitin switch in the activation of Parkin

por Sauvé, Véronique, Lilov, Asparouh, Seirafi, Marjan, Vranas, Marta, Rasool, Shafqat, Kozlov, Guennadi, Sprules, Tara, Wang, Jimin, Trempe, Jean-François, Gehring, Kalle
Publicado 2015

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

por Riedinger, Christiane, Boehringer, Jonas, Trempe, Jean-Francois, Lowe, Edward D., Brown, Nicholas R., Gehring, Kalle, Noble, Martin E. M., Gordon, Colin, Endicott, Jane A.
Publicado 2010

Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria

por Vranas, Marta, Lu, Yang, Rasool, Shafqat, Croteau, Nathalie, Krett, Jonathan D., Sauvé, Véronique, Gehring, Kalle, Fon, Edward A., Durcan, Thomas M., Trempe, Jean-François
Publicado 2022

Corrigendum: Clinical and genetic analysis of Costa Rican patients with Parkinson's disease

por Torrealba-Acosta, Gabriel, Yu, Eric, Lobo-Prada, Tanya, Ruíz-Martínez, Javier, Gorostidi-Pagola, Ana, Gan-Or, Ziv, Carazo-Céspedes, Kenneth, Trempe, Jean-François, Mata, Ignacio F., Fornaguera-Trías, Jaime
Publicado 2023

Clinical and Genetic Analysis of Costa Rican Patients With Parkinson's Disease

por Torrealba-Acosta, Gabriel, Yu, Eric, Lobo-Prada, Tanya, Ruíz-Martínez, Javier, Gorostidi-Pagola, Ana, Gan-Or, Ziv, Carazo-Céspedes, Kenneth, Trempe, Jean-François, Mata, Ignacio F., Fornaguera-Trías, Jaime
Publicado 2021

Structure-based design and characterization of Parkin-activating mutations

por Stevens, Michael U, Croteau, Nathalie, Eldeeb, Mohamed A, Antico, Odetta, Zeng, Zhi Wei, Toth, Rachel, Durcan, Thomas M, Springer, Wolfdieter, Fon, Edward A, Muqit, Miratul MK, Trempe, Jean-François
Publicado 2023

Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family

por Trempe, Jean-François, Šašková, Klára Grantz, Sivá, Monika, Ratcliffe, Colin D. H., Veverka, Václav, Hoegl, Annabelle, Ménade, Marie, Feng, Xin, Shenker, Solomon, Svoboda, Michal, Kožíšek, Milan, Konvalinka, Jan, Gehring, Kalle
Publicado 2016

The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications

por Khalifa, Ahmad Abdelzaher Zaki, Ichikawa, Muneyoshi, Dai, Daniel, Kubo, Shintaroh, Black, Corbin Steven, Peri, Katya, McAlear, Thomas S, Veyron, Simon, Yang, Shun Kai, Vargas, Javier, Bechstedt, Susanne, Trempe, Jean-François, Bui, Khanh Huy
Publicado 2020

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

por Sivá, Monika, Svoboda, Michal, Veverka, Václav, Trempe, Jean-François, Hofmann, Kay, Kožíšek, Milan, Hexnerová, Rozálie, Sedlák, František, Belza, Jan, Brynda, Jiří, Šácha, Pavel, Hubálek, Martin, Starková, Jana, Flaisigová, Iva, Konvalinka, Jan, Šašková, Klára Grantz
Publicado 2016

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

por McLelland, Gian-Luca, Goiran, Thomas, Yi, Wei, Dorval, Geneviève, Chen, Carol X, Lauinger, Nadine D, Krahn, Andrea I, Valimehr, Sepideh, Rakovic, Aleksandar, Rouiller, Isabelle, Durcan, Thomas M, Trempe, Jean-François, Fon, Edward A
Publicado 2018

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson’s disease

por Fava, Vinicius M., Xu, Yong Zhong, Lettre, Guillaume, Van Thuc, Nguyen, Orlova, Marianna, Thai, Vu Hong, Tao, Shao, Croteau, Nathalie, Eldeeb, Mohamed A., MacDougall, Emma J., Cambri, Geison, Lahiri, Ramanuj, Adams, Linda, Fon, Edward A., Trempe, Jean-François, Cobat, Aurélie, Alcaïs, Alexandre, Abel, Laurent, Schurr, Erwin
Publicado 2019