In Vitro Phase I Metabolism of CRV431, a Novel Oral Drug Candidate for Chronic Hepatitis B

por Trepanier, Daniel J., Ure, Daren R., Foster, Robert T.
Publicado 2017

The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice

por Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
Publicado 2019

The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

por Gallay, Philippe A., Bobardt, Michael D., Chatterji, Udayan, Trepanier, Daniel J., Ure, Daren, Ordonez, Cosme, Foster, Robert
Publicado 2015

A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models

por Kuo, Joseph, Bobardt, Michael, Chatterji, Udayan, Mayo, Patrick R., Trepanier, Daniel J., Foster, Robert T., Gallay, Philippe, Ure, Daren R.
Publicado 2019

Rencofilstat, a cyclophilin inhibitor: A phase 2a, multicenter, single‐blind, placebo‐controlled study in F2/F3 NASH

por Harrison, Stephen A., Mayo, Patrick R., Hobbs, Todd M., Canizares, Carlos, Foster, Erin P., Zhao, Caroline, Ure, Daren R., Trepanier, Daniel J., Greytok, Jill A., Foster, Robert T.
Publicado 2022