Comparison of Glaucoma-Relevant Transcriptomic Datasets Identifies Novel Drug Targets for Retinal Ganglion Cell Neuroprotection

por Enz, Tim J., Tribble, James R., Williams, Pete A.
Publicado 2021

Digestion of the glycosaminoglycan extracellular matrix by chondroitinase ABC supports retinal ganglion cell dendritic preservation in a rodent model of experimental glaucoma

por Tribble, James R., Williams, Pete A., Caterson, Bruce, Sengpiel, Frank, Morgan, James E.
Publicado 2018

Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice

por Tribble, James R., Harder, Jeffrey M., Williams, Pete A., John, Simon W. M.
Publicado 2020

Retinal Ganglion Cell Degeneration in a Rat Magnetic Bead Model of Ocular Hypertensive Glaucoma

por Tribble, James R., Otmani, Amin, Kokkali, Eirini, Lardner, Emma, Morgan, James E., Williams, Pete A.
Publicado 2021

Valproic Acid Reduces Neuroinflammation to Provide Retinal Ganglion Cell Neuroprotection in the Retina Axotomy Model

por Tribble, James R., Kastanaki, Elizabeth, Uslular, A. Berşan, Rutigliani, Carola, Enz, Tim J., Williams, Pete A.
Publicado 2022

Widespread retina and optic nerve neuroinflammation in enucleated eyes from glaucoma patients

por Rutigliani, Carola, Tribble, James R., Hagström, Anna, Lardner, Emma, Jóhannesson, Gauti, Stålhammar, Gustav, Williams, Pete A.
Publicado 2022

Targeting Diet and Exercise for Neuroprotection and Neurorecovery in Glaucoma

por Tribble, James R., Hui, Flora, Jöe, Melissa, Bell, Katharina, Chrysostomou, Vicki, Crowston, Jonathan G., Williams, Pete A.
Publicado 2021

NAD salvage pathway machinery expression in normal and glaucomatous retina and optic nerve

por Tribble, James R., Hagström, Anna, Jusseaume, Kenza, Lardner, Emma, Wong, Raymond Ching-Bong, Stålhammar, Gustav, Williams, Pete A.
Publicado 2023

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters

por Nieuwenhuis, Bart, Laperrousaz, Elise, Tribble, James R., Verhaagen, Joost, Fawcett, James W., Martin, Keith R., Williams, Pete A., Osborne, Andrew
Publicado 2023

Pyrroloquinoline quinone drives ATP synthesis in vitro and in vivo and provides retinal ganglion cell neuroprotection

por Canovai, Alessio, Tribble, James R., Jöe, Melissa, Westerlund, Daniela Y., Amato, Rosario, Trounce, Ian A., Dal Monte, Massimo, Williams, Pete A.
Publicado 2023

Comparative Assessment of Retinal Blood Flow Velocity Changes Following Brimonidine and Brinzolamide Administration Using Retinal Function Imaging

por Enz, Tim J., Bittner, Mario, Tribble, James R., Williams, Pete A., Thiel, Michael A., Schmid, Martin K., Bachmann, Lucas M., Bochmann, Frank
Publicado 2022

Midget retinal ganglion cell dendritic and mitochondrial degeneration is an early feature of human glaucoma

por Tribble, James R, Vasalauskaite, Asta, Redmond, Tony, Young, Robert D, Hassan, Shoaib, Fautsch, Michael P, Sengpiel, Frank, Williams, Pete A, Morgan, James E
Publicado 2019

When Is a Control Not a Control? Reactive Microglia Occur Throughout the Control Contralateral Pathway of Retinal Ganglion Cell Projections in Experimental Glaucoma

por Tribble, James R., Kokkali, Eirini, Otmani, Amin, Plastino, Flavia, Lardner, Emma, Vohra, Rupali, Kolko, Miriam, André, Helder, Morgan, James E., Williams, Pete A.
Publicado 2021

Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma

por Williams, Pete A., Tribble, James R., Pepper, Keating W., Cross, Stephen D., Morgan, B Paul, Morgan, James E., John, Simon W. M., Howell, Gareth R.
Publicado 2016

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

por Gustavsson, Simon T., Enz, Tim J., Tribble, James R., Nilsson, Mattias, Lindqvist, Anna, Lindén, Christina, Hagström, Anna, Rutigliani, Carola, Lardner, Emma, Stålhammar, Gustav, Williams, Pete A., Jóhannesson, Gauti
Publicado 2023

Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS

por Petrova, Veselina, Pearson, Craig S., Ching, Jared, Tribble, James R., Solano, Andrea G., Yang, Yunfei, Love, Fiona M., Watt, Robert J., Osborne, Andrew, Reid, Evan, Williams, Pete A., Martin, Keith R., Geller, Herbert M., Eva, Richard, Fawcett, James W.
Publicado 2020

Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

por Tribble, James R., Otmani, Amin, Sun, Shanshan, Ellis, Sevannah A., Cimaglia, Gloria, Vohra, Rupali, Jöe, Melissa, Lardner, Emma, Venkataraman, Abinaya P., Domínguez-Vicent, Alberto, Kokkali, Eirini, Rho, Seungsoo, Jóhannesson, Gauti, Burgess, Robert W., Fuerst, Peter G., Brautaset, Rune, Kolko, Miriam, Morgan, James E., Crowston, Jonathan G., Votruba, Marcela, Williams, Pete A.
Publicado 2021