Cell surface GRP78 regulates TGFβ1-mediated profibrotic responses via TSP1 in diabetic kidney disease

por Trink, Jackie, Ahmed, Usman, O’Neil, Kian, Li, Renzhong, Gao, Bo, Krepinsky, Joan C.
Publicado 2023

Both sexes develop DKD in the CD1 uninephrectomized streptozotocin mouse model

por Trink, Jackie, Nmecha, Ifeanyi Kennedy, Zhang, Dan, MacDonald, Melissa, Gao, Bo, Krepinsky, Joan C.
Publicado 2023

Integrin β1/Cell Surface GRP78 Complex Regulates TGFβ1 and Its Profibrotic Effects in Response to High Glucose

por Trink, Jackie, Li, Renzhong, Squire, Evan, O’Neil, Kian, Zheng, Phoebe, Gao, Bo, Krepinsky, Joan C.
Publicado 2022

Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease

por Soomro, Asfia, Trink, Jackie, O’Neil, Kian, Li, Renzhong, Naiel, Safaa, Gao, Bo, Ask, Kjetil, Krepinsky, Joan C.
Publicado 2021

Activated Alpha 2-Macroglobulin Is a Novel Mediator of Mesangial Cell Profibrotic Signaling in Diabetic Kidney Disease

por Trink, Jackie, Li, Renzhong, Palarasah, Yaseelan, Troyanov, Stéphan, Andersen, Thomas E., Sidelmann, Johannes J., Inman, Mark D., Pizzo, Salvatore V., Gao, Bo, Krepinsky, Joan C.
Publicado 2021