Role of integrative structural biology in understanding transcriptional initiation

por Trnka, Michael J., Pellarin, Riccardo, Robinson, Philip J.
Publicado 2019

In-Cell Chemical Crosslinking Identifies Hotspots for SQSTM-1/p62-IκBα Interaction That Underscore a Critical Role of p62 in Limiting NF-κB Activation Through IκBα Stabilization...

por Liu, Yi, Trnka, Michael J., He, Liang, Burlingame, A.L., Correia, Maria Almira
Publicado 2023

The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h

por Gamarra, Nathan, Johnson, Stephanie L, Trnka, Michael J, Burlingame, Alma L, Narlikar, Geeta J
Publicado 2018

Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities

por Sanchez, Nicholas A., Kallweit, Lena M., Trnka, Michael J., Clemmer, Charles L., Al-Sady, Bassem
Publicado 2021

Autoinhibition of the GEF activity of cytoskeletal regulatory protein Trio is disrupted in neurodevelopmental disorder-related genetic variants

por Bircher, Josie E., Corcoran, Ellen E., Lam, TuKiet T., Trnka, Michael J., Koleske, Anthony J.
Publicado 2022

SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

por Jack, Amanda, Ferro, Luke S., Trnka, Michael J., Wehri, Eddie, Nadgir, Amrut, Nguyenla, Xammy, Costa, Katelyn, Stanley, Sarah, Schaletzky, Julia, Yildiz, Ahmet
Publicado 2021

LEM2 phase separation governs ESCRT-mediated nuclear envelope reformation

por von Appen, Alexander, LaJoie, Dollie, Johnson, Isabel E., Trnka, Michael J., Pick, Sarah M., Burlingame, Alma L., Ullman, Katharine S., Frost, Adam
Publicado 2020

Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides

por Zhang, Meng Yao, Yang, Hyunjun, Ortiz, Gloria, Trnka, Michael J., Petronikolou, Nektaria, Burlingame, Alma L., DeGrado, William F., Fujimori, Danica Galonić
Publicado 2022

An ER translocon for multi-pass membrane protein biogenesis

por McGilvray, Philip T, Anghel, S Andrei, Sundaram, Arunkumar, Zhong, Frank, Trnka, Michael J, Fuller, James R, Hu, Hong, Burlingame, Alma L, Keenan, Robert J
Publicado 2020

SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

por Jack, Amanda, Ferro, Luke S., Trnka, Michael J., Wehri, Eddie, Nadgir, Amrut, Nguyenla, Xammy, Fox, Douglas, Costa, Katelyn, Stanley, Sarah, Schaletzky, Julia, Yildiz, Ahmet
Publicado 2021

SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

por Jack, Amanda, Ferro, Luke, Trnka, Michael J., Wehri, Eddie, Nadgir, Amrut, Nguyenla, Xammy, Fox, Douglas, Costa, Katelyn, Stanley, Sarah, Schaletzky, Julia, Yildiz, Ahmet
Publicado 2022

Molecular architecture of the yeast Mediator complex

por Robinson, Philip J, Trnka, Michael J, Pellarin, Riccardo, Greenberg, Charles H, Bushnell, David A, Davis, Ralph, Burlingame, Alma L, Sali, Andrej, Kornberg, Roger D
Publicado 2015

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

por Larson, Adam G., Elnatan, Daniel, Keenen, Madeline M., Trnka, Michael J., Johnston, Jonathan B., Burlingame, Alma L., Agard, David A., Redding, Sy, Narlikar, Geeta J.
Publicado 2017

Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling

por Longbotham, James E., Chio, Cynthia M., Dharmarajan, Venkatasubramanian, Trnka, Michael J., Torres, Idelisse Ortiz, Goswami, Devrishi, Ruiz, Karen, Burlingame, Alma L., Griffin, Patrick R., Fujimori, Danica Galonić
Publicado 2019

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study

por Iacobucci, Claudio, Piotrowski, Christine, Aebersold, Ruedi, Amaral, Bruno C., Andrews, Philip, Bernfur, Katja, Borchers, Christoph, Brodie, Nicolas I., Bruce, James E., Cao, Yong, Chaignepain, Stéphane, Chavez, Juan D., Claverol, Stéphane, Cox, Jürgen, Davis, Trisha, Degliesposti, Gianluca, Dong, Meng-Qiu, Edinger, Nufar, Emanuelsson, Cecilia, Gay, Marina, Götze, Michael, Gomes-Neto, Francisco, Gozzo, Fabio C., Gutierrez, Craig, Haupt, Caroline, Heck, Albert J. R., Herzog, Franz, Huang, Lan, Hoopmann, Michael R., Kalisman, Nir, Klykov, Oleg, Kukačka, Zdeněk, Liu, Fan, MacCoss, Michael J., Mechtler, Karl, Mesika, Ravit, Moritz, Robert L., Nagaraj, Nagarjuna, Nesati, Victor, Neves-Ferreira, Ana G. C., Ninnis, Robert, Novák, Petr, O’Reilly, Francis J., Pelzing, Matthias, Petrotchenko, Evgeniy, Piersimoni, Lolita, Plasencia, Manolo, Pukala, Tara, Rand, Kasper D., Rappsilber, Juri, Reichmann, Dana, Sailer, Carolin, Sarnowski, Chris P., Scheltema, Richard A., Schmidt, Carla, Schriemer, David C., Shi, Yi, Skehel, J. Mark, Slavin, Moriya, Sobott, Frank, Solis-Mezarino, Victor, Stephanowitz, Heike, Stengel, Florian, Stieger, Christian E., Trabjerg, Esben, Trnka, Michael, Vilaseca, Marta, Viner, Rosa, Xiang, Yufei, Yilmaz, Sule, Zelter, Alex, Ziemianowicz, Daniel, Leitner, Alexander, Sinz, Andrea
Publicado 2019