Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A

por Kelly, Richard D. W., Mahmud, Arsalan, McKenzie, Matthew, Trounce, Ian A., St John, Justin C.
Publicado 2012

Exercise reverses age‐related vulnerability of the retina to injury by preventing complement‐mediated synapse elimination via a BDNF‐dependent pathway

por Chrysostomou, Vicki, Galic, Sandra, van Wijngaarden, Peter, Trounce, Ian A., Steinberg, Gregory R., Crowston, Jonathan G.
Publicado 2016

Generation of ρ(0) cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses

por Kukat, Alexandra, Kukat, Christian, Brocher, Jan, Schäfer, Ingo, Krohne, Georg, Trounce, Ian A., Villani, Gaetano, Seibel, Peter
Publicado 2008

Pioglitazone and Deoxyribonucleoside Combination Treatment Increases Mitochondrial Respiratory Capacity in m.3243A>G MELAS Cybrid Cells

por Burgin, Harrison J., Lopez Sanchez, M. Isabel G., Smith, Craig M., Trounce, Ian A., McKenzie, Matthew
Publicado 2020

Pyrroloquinoline quinone drives ATP synthesis in vitro and in vivo and provides retinal ganglion cell neuroprotection

por Canovai, Alessio, Tribble, James R., Jöe, Melissa, Westerlund, Daniela Y., Amato, Rosario, Trounce, Ian A., Dal Monte, Massimo, Williams, Pete A.
Publicado 2023

Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta

por Lopez Sanchez, M. Isabel G., Waugh, Hayley S., Tsatsanis, Andrew, Wong, Bruce X., Crowston, Jonathan G., Duce, James A., Trounce, Ian A.
Publicado 2017

Mitochondrial Oxidative Phosphorylation Compensation May Preserve Vision in Patients with OPA1-Linked Autosomal Dominant Optic Atrophy

por Van Bergen, Nicole J., Crowston, Jonathan G., Kearns, Lisa S., Staffieri, Sandra E., Hewitt, Alex W., Cohn, Amy C., Mackey, David A., Trounce, Ian A.
Publicado 2011

Nuclear response to divergent mitochondrial DNA genotypes modulates the interferon immune response

por Lopez Sanchez, M. Isabel G., Ziemann, Mark, Bachem, Annabell, Makam, Rahul, Crowston, Jonathan G., Pinkert, Carl A., McKenzie, Matthew, Bedoui, Sammy, Trounce, Ian A.
Publicado 2020

Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy

por Van Bergen, Nicole J, Crowston, Jonathan G., Craig, Jamie E., Burdon, Kathryn P., Kearns, Lisa S., Sharma, Shiwani, Hewitt, Alex W., Mackey, David A., Trounce, Ian A.
Publicado 2015

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

por Lee, William T, Sun, Xin, Tsai, Te-Sha, Johnson, Jacqueline L, Gould, Jodee A, Garama, Daniel J, Gough, Daniel J, McKenzie, Matthew, Trounce, Ian A, St. John, Justin C
Publicado 2017

Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma

por Singh, Larry N., Crowston, Jonathan G., Lopez Sanchez, M. Isabel G., Van Bergen, Nicole J., Kearns, Lisa S., Hewitt, Alex W., Yazar, Seyhan, Mackey, David A., Wallace, Douglas C., Trounce, Ian A.
Publicado 2018

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

por Cimdins, Kathryn, Waugh, Hayley S., Chrysostomou, Vicki, Lopez Sanchez, M. Isabel G., Johannsen, Vanessa A., Cook, Mark J., Crowston, Jonathan G., Hill, Andrew F., Duce, James A., Bush, Ashley I., Trounce, Ian A.
Publicado 2019

Characterization of the retinal pigment epithelium in Friedreich ataxia

por Crombie, Duncan E., Van Bergen, Nicole, Davidson, Kathryn C., Anjomani Virmouni, Sara, Mckelvie, Penny A., Chrysostomou, Vicki, Conquest, Alison, Corben, Louise A., Pook, Mark A., Kulkarni, Tejal, Trounce, Ian A., Pera, Martin F., Delatycki, Martin B., Pébay, Alice
Publicado 2015

Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity

por Jorgensen, Sebastian Beck, O’Neill, Hayley M., Sylow, Lykke, Honeyman, Jane, Hewitt, Kimberly A., Palanivel, Rengasamy, Fullerton, Morgan D., Öberg, Lisa, Balendran, Anudharan, Galic, Sandra, van der Poel, Chris, Trounce, Ian A., Lynch, Gordon S., Schertzer, Jonathan D., Steinberg, Gregory R.
Publicado 2013

Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy

por Wong, Raymond C.B., Lim, Shiang Y., Hung, Sandy S.C., Jackson, Stacey, Khan, Shahnaz, Van Bergen, Nicole J., De Smit, Elisabeth, Liang, Helena H., Kearns, Lisa S, Clarke, Linda, Mackey, David A., Hewitt, Alex W., Trounce, Ian A., Pébay, Alice
Publicado 2017

MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data

por Singh, Larry N., Ennis, Brian, Loneragan, Bryn, Tsao, Noah L., Lopez Sanchez, M. Isabel G., Li, Jianping, Acheampong, Patrick, Tran, Oanh, Trounce, Ian A., Zhu, Yuankun, Potluri, Prasanth, Emanuel, Beverly S., Rader, Daniel J., Arany, Zoltan, Damrauer, Scott M., Resnick, Adam C., Anderson, Stewart A., Wallace, Douglas C.
Publicado 2021

Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency

por Crombie, Duncan E., Curl, Claire L., Raaijmakers, Antonia JA, Sivakumaran, Priyadharshini, Kulkarni, Tejal, Wong, Raymond CB, Minami, Itsunari, Evans-Galea, Marguerite V., Lim, Shiang Y., Delbridge, Lea, Corben, Louise A., Dottori, Mirella, Nakatsuji, Norio, Trounce, Ian A., Hewitt, Alex W., Delatycki, Martin B., Pera, Martin F., Pébay, Alice
Publicado 2017