Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences

por Mahler, Michael, van Schaarenburg, Rosanne A., Trouw, Leendert A.
Publicado 2013

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

por Trouw, Leendert A., Nilsson, Sara C., Gonçalves, Isabel, Landberg, Göran, Blom, Anna M.
Publicado 2005

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

por Verheul, Marije K., Vierboom, Michel P. M., ’t Hart, Bert A., Toes, Rene E. M., Trouw, Leendert A.
Publicado 2017

C4b-Binding Protein Is Present in Affected Areas of Myocardial Infarction during the Acute Inflammatory Phase and Covers a Larger Area than C3

por Trouw, Leendert A., Okroj, Marcin, Kupreishvili, Koba, Landberg, Göran, Johansson, Bengt, Niessen, Hans W. M., Blom, Anna M.
Publicado 2008

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodie...

por Boeters, Debbie M., Trouw, Leendert A., van der Helm-van Mil, Annette H. M., van Steenbergen, Hanna W.
Publicado 2018

Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the art...

por van Dijk, Bastiaan T., Trouw, Leendert A., van der Helm-van Mil, Annette H. M., Huizinga, Tom W. J.
Publicado 2020

Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains

por Abendstein, Leoni, Dijkstra, Douwe J., Tjokrodirijo, Rayman T. N., van Veelen, Peter A., Trouw, Leendert A., Hensbergen, Paul J., Sharp, Thomas H.
Publicado 2023

Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis

por Dijkman, Karin, Lubbers, Rosalie, Borggreven, Nicole V., Ottenhoff, Tom H. M., Joosten, Simone A., Trouw, Leendert A., Verreck, Frank A. W.
Publicado 2020

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with...

por Brink, Mikael, Verheul, Marije K, Rönnelid, Johan, Berglin, Ewa, Holmdahl, Rikard, Toes, Rene EM, Klareskog, Lars, Trouw, Leendert A, Rantapää-Dahlqvist, Solbritt
Publicado 2015

Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays

por Vos, Ine, Van Mol, Christof, Trouw, Leendert A., Mahler, Michael, Bakker, Jaap A., Van Offel, Jan, De Clerck, Luc, Huizinga, Tom W.
Publicado 2017

Antibodies Specific for Carbamylated Proteins Precede the Onset of Clinical Symptoms in Mice with Collagen Induced Arthritis

por Stoop, Jeroen N., Liu, Bi-Sheng, Shi, Jing, Jansen, Diahann T. S. L., Hegen, Martin, Huizinga, Tom W. J., Trouw, Leendert A., Toes, René E. M.
Publicado 2014

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

por Brink, Mikael, Hansson, Monika, Mathsson-Alm, Linda, Wijayatunga, Priyantha, Verheul, Marije K., Trouw, Leendert A., Holmdahl, Rikard, Rönnelid, Johan, Klareskog, Lars, Rantapää-Dahlqvist, Solbritt
Publicado 2016

Complement Activation in Patients With Diabetic Nephropathy

por Bus, Pascal, Chua, Jamie S., Klessens, Céline Q.F., Zandbergen, Malu, Wolterbeek, Ron, van Kooten, Cees, Trouw, Leendert A., Bruijn, Jan A., Baelde, Hans J.
Publicado 2017

Antibodies against carbamylated proteins and cyclic citrullinated peptides in systemic lupus erythematosus: results from two well-defined European cohorts

por Ziegelasch, Michael, van Delft, Myrthe A. M., Wallin, Philip, Skogh, Thomas, Magro-Checa, César, Steup-Beekman, Gerda M., Trouw, Leendert A., Kastbom, Alf, Sjöwall, Christopher
Publicado 2016

The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA

por Suwannalai, Parawee, Willemze, Annemiek, van Toorn, Linda, Stoeken-Rijsbergen, Gerrie, Levarht, Nivine, Drijfhout, Jan Wouter, J Huizinga, Tom W, M Toes, Rene E, Trouw, Leendert A
Publicado 2011

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

por Foltyn Zadura, Anna, Zipfel, Peter F, Bokarewa, Maria I, Sturfelt, Gunnar, Jönsen, Andreas, Nilsson, Sara C, Hillarp, Andreas, Saxne, Tore, Trouw, Leendert A, Blom, Anna M
Publicado 2012

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk...

por Humphreys, Jennifer H, Verheul, Marije K, Barton, Anne, MacGregor, Alexander J, Lunt, Mark, Toes, Rene EM, Symmons, Deborah PM, Trouw, Leendert A, Verstappen, Suzanne MM
Publicado 2016

Autoantibodies against specific post-translationally modified proteins are present in patients with lupus and associate with major neuropsychiatric manifestations

por Monahan, Rory C, van den Beukel, Michelle D, Borggreven, Nicole V, Fronczek, Rolf, Huizinga, Tom W J, Kloppenburg, Margreet, Steup-Beekman, Gerda M, Trouw, Leendert A
Publicado 2022

C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

por van Schaarenburg, Rosanne A., Magro-Checa, César, Bakker, Jaap A., Teng, Y. K. Onno, Bajema, Ingeborg M., Huizinga, Tom W., Steup-Beekman, Gerda M., Trouw, Leendert A.
Publicado 2016

PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation

por Noone, Dylan P., Dijkstra, Douwe J., van der Klugt, Teun T., van Veelen, Peter A., de Ru, Arnoud H., Hensbergen, Paul J., Trouw, Leendert A., Sharp, Thomas H.
Publicado 2022