Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS

por Trowbridge, Jennifer J., Starczynowski, Daniel T.
Publicado 2021

Hematopoietic stem cell aging and leukemia transformation

por Colom Díaz, Patricia A., Mistry, Jayna J., Trowbridge, Jennifer J.
Publicado 2023

Characterization of an Osmr Conditional Knockout Mouse Model

por Schwartz, Logan S., Saxl, Ruth L., Stearns, Tim, Trowbridge, Jennifer J.
Publicado 2023

The lethal sex gap: COVID-19

por Márquez, Eladio J., Trowbridge, Jennifer, Kuchel, George A., Banchereau, Jacques, Ucar, Duygu
Publicado 2020

Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging

por Young, Kira, Borikar, Sneha, Bell, Rebecca, Kuffler, Lauren, Philip, Vivek, Trowbridge, Jennifer J.
Publicado 2016

Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells

por George, Joshy, Uyar, Asli, Young, Kira, Kuffler, Lauren, Waldron-Francis, Kaiden, Marquez, Eladio, Ucar, Duygu, Trowbridge, Jennifer J.
Publicado 2016

A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2

por Snow, Jonathan W., Trowbridge, Jennifer J., Fujiwara, Tohru, Emambokus, Nikla E., Grass, Jeffrey A., Orkin, Stuart H., Bresnick, Emery H.
Publicado 2010

Cell origin–dependent cooperativity of mutant Dnmt3a and Npm1 in clonal hematopoiesis and myeloid malignancy

por SanMiguel, Jennifer M., Eudy, Elizabeth, Loberg, Matthew A., Miles, Linde A., Stearns, Tim, Mistry, Jayna J., Rauh, Michael J., Levine, Ross L., Trowbridge, Jennifer J.
Publicado 2022

Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis

por SanMiguel, Jennifer M., Eudy, Elizabeth, Loberg, Matthew A., Young, Kira A., Mistry, Jayna J., Mujica, Kristina D., Schwartz, Logan S., Stearns, Timothy M., Challen, Grant A., Trowbridge, Jennifer J.
Publicado 2022

Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis

por Loberg, Matthew A., Bell, Rebecca K., Goodwin, Leslie O., Eudy, Elizabeth, Miles, Linde A., SanMiguel, Jennifer M., Young, Kira, Bergstrom, David E., Levine, Ross L., Schneider, Rebekka K., Trowbridge, Jennifer J.
Publicado 2019

Variation in histone configurations correlates with gene expression across nine inbred strains of mice

por Tyler, Anna L., Spruce, Catrina, Kursawe, Romy, Haber, Annat, Ball, Robyn L., Pitman, Wendy A., Fine, Alexander D., Raghupathy, Narayanan, Walker, Michael, Philip, Vivek M., Baker, Christopher L., Mahoney, J. Matthew, Churchill, Gary A., Trowbridge, Jennifer J., Stitzel, Michael L., Paigen, Kenneth, Petkov, Petko M., Carter, Gregory W.
Publicado 2023

Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy

por Wu, Hsin-Chieh, Rérolle, Domitille, Berthier, Caroline, Hleihel, Rita, Sakamoto, Takashi, Quentin, Samuel, Benhenda, Shirine, Morganti, Claudia, Wu, Chengchen, Conte, Lidio, Rimsky, Sylvie, Sebert, Marie, Clappier, Emmanuelle, Souquere, Sylvie, Gachet, Stéphanie, Soulier, Jean, Durand, Sylvère, Trowbridge, Jennifer J., Bénit, Paule, Rustin, Pierre, El Hajj, Hiba, Raffoux, Emmanuel, Ades, Lionel, Itzykson, Raphael, Dombret, Hervé, Fenaux, Pierre, Espeli, Olivier, Kroemer, Guido, Brunetti, Lorenzo, Mak, Tak W., Lallemand-Breitenbach, Valérie, Bazarbachi, Ali, Falini, Brunangelo, Ito, Keisuke, Martelli, Maria Paola, de Thé, Hugues
Publicado 2021