Targeting tumor-associated macrophages for successful immunotherapy of ovarian carcinoma

por Truxova, Iva, Cibula, David, Spisek, Radek, Fucikova, Jitka
Publicado 2023

Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma

por Partlová, Simona, Bouček, Jan, Kloudová, Kamila, Lukešová, Eva, Zábrodský, Michal, Grega, Marek, Fučíková, Jitka, Truxová, Iva, Tachezy, Ruth, Špíšek, Radek, Fialová, Anna
Publicado 2015

Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors w...

por MIKYŠKOVÁ, ROMANA, ŠTĚPÁNEK, IVAN, INDROVÁ, MARIE, BIEBLOVÁ, JANA, ŠÍMOVÁ, JANA, TRUXOVÁ, IVA, MOSEROVÁ, IRENA, FUČÍKOVÁ, JITKA, BARTŮŇKOVÁ, JIŘINA, ŠPÍŠEK, RADEK, REINIŠ, MILAN
Publicado 2015

Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma

por Ligtenberg, Maarten A., Pico de Coaña, Yago, Shmushkovich, Taisia, Yoshimoto, Yuya, Truxova, Iva, Yang, Yuan, Betancur-Boissel, Monica, Eliseev, Alexey V., Wolfson, Alexey D., Kiessling, Rolf
Publicado 2018

TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients

por Rakova, Jana, Truxova, Iva, Holicek, Peter, Salek, Cyril, Hensler, Michal, Kasikova, Lenka, Pasulka, Josef, Holubova, Monika, Kovar, Marek, Lysak, Daniel, Kline, Justin P., Racil, Zdenek, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Publicado 2021

Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists

por Lövgren, Tanja, Sarhan, Dhifaf, Truxová, Iva, Choudhary, Bhavesh, Maas, Roeltje, Melief, Jeroen, Nyström, Maria, Edbäck, Ulrika, Vermeij, Renee, Scurti, Gina, Nishimura, Michael, Masucci, Giuseppe, Karlsson-Parra, Alex, Lundqvist, Andreas, Adamson, Lars, Kiessling, Rolf
Publicado 2017

Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients

por Truxova, Iva, Kasikova, Lenka, Salek, Cyril, Hensler, Michal, Lysak, Daniel, Holicek, Peter, Bilkova, Pavla, Holubova, Monika, Chen, Xiufen, Mikyskova, Romana, Reinis, Milan, Kovar, Marek, Tomalova, Barbora, Kline, Justin P., Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Publicado 2020

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients

por Kasikova, Lenka, Hensler, Michal, Truxova, Iva, Skapa, Petr, Laco, Jan, Belicova, Lucie, Praznovec, Ivan, Vosahlikova, Sarka, Halaska, Michael J., Brtnicky, Tomas, Rob, Lukas, Presl, Jiri, Kostun, Jan, Cremer, Isabelle, Ryska, Ales, Kroemer, Guido, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Publicado 2019

Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients

por Holicek, Peter, Truxova, Iva, Rakova, Jana, Salek, Cyril, Hensler, Michal, Kovar, Marek, Reinis, Milan, Mikyskova, Romana, Pasulka, Josef, Vosahlikova, Sarka, Remesova, Hana, Valentova, Iva, Lysak, Daniel, Holubova, Monika, Kaspar, Petr, Prochazka, Jan, Kasikova, Lenka, Spisek, Radek, Galluzzi, Lorenzo, Fucikova, Jitka
Publicado 2023

A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer

por D’Amico, Lucia, Menzel, Ulrike, Prummer, Michael, Müller, Philipp, Buchi, Mélanie, Kashyap, Abhishek, Haessler, Ulrike, Yermanos, Alexander, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Wolter, Fabian I., Beerli, Roger R., Truxova, Iva, Radek, Špíšek, Vlajnic, Tatjana, Grawunder, Ulf, Reddy, Sai, Zippelius, Alfred
Publicado 2019

Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients

por Truxova, Iva, Kasikova, Lenka, Hensler, Michal, Skapa, Petr, Laco, Jan, Pecen, Ladislav, Belicova, Lucie, Praznovec, Ivan, Halaska, Michael J., Brtnicky, Tomas, Salkova, Eva, Rob, Lukas, Kodet, Roman, Goc, Jeremy, Sautes-Fridman, Catherine, Fridman, Wolf Herman, Ryska, Ales, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Publicado 2018

M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer

por Hensler, Michal, Kasikova, Lenka, Fiser, Karel, Rakova, Jana, Skapa, Petr, Laco, Jan, Lanickova, Tereza, Pecen, Ladislav, Truxova, Iva, Vosahlikova, Sarka, Moserova, Irena, Praznovec, Ivan, Drochytek, Vit, Rehackova, Martina, Brtnicky, Tomas, Rob, Lukas, Benes, Vladimir, Pistolic, Jelena, Sojka, Ludek, Ryska, Ales, Sautes-Fridman, Catherine, Fridman, Wolf Herve, Galluzzi, Lorenzo, Spisek, Radek, Fucikova, Jitka
Publicado 2020