The Consequence of Immune Suppressive Cells in the Use of Therapeutic Cancer Vaccines and Their Importance in Immune Monitoring

por Vergati, Matteo, Schlom, Jeffrey, Tsang, Kwong Y.
Publicado 2011

Strategies for Cancer Vaccine Development

por Vergati, Matteo, Intrivici, Chiara, Huen, Ngar-Yee, Schlom, Jeffrey, Tsang, Kwong Y.
Publicado 2010

Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

por Tucker, Jo A., Jochems, Caroline, Gulley, James L., Schlom, Jeffrey, Tsang, Kwong Y.
Publicado 2012

Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells

por Gameiro, Sofia R., Malamas, Anthony S., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W.
Publicado 2016

Long-Term Survival and PSA Control with Radiation and Immunotherapy for Node Positive Prostate Cancer

por Kamrava, M., Tsang, Kwong Y., Madan, R. A., Kaushal, A., Coleman, C. N., Gulley, J.
Publicado 2009

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing

por Gameiro, Sofia R., Jammed, Momodou L., Wattenberg, Max M., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W.
Publicado 2013

Generation of human T cells directed against an agonist epitope of Brachyury, a transcription factor involved in human tumor cell epithelial to mesenchymal transition (EMT)

por Boyerinas, Benjamin, Tucker, Jo A, Poole, Diane J, Jochéms, Caroline, Palena, Claudia, Schlom, Jeffrey, Tsang, Kwong Y
Publicado 2013

An IL-15 Superagonist, ALT-803, Enhances Antibody-Dependent Cell-Mediated Cytotoxicity Elicited by the Monoclonal Antibody NEO-201 Against Human Carcinoma Cells

por Fantini, Massimo, David, Justin M., Wong, Hing C., Annunziata, Christina M., Arlen, Philip M., Tsang, Kwong Y.
Publicado 2019

Enhanced killing of chordoma cells by antibody-dependent cell-mediated cytotoxicity employing the novel anti-PD-L1 antibody avelumab

por Fujii, Rika, Friedman, Eitan R., Richards, Jacob, Tsang, Kwong Y., Heery, Christopher R., Schlom, Jeffrey, Hodge, James W.
Publicado 2016

Identification of the O-Glycan Epitope Targeted by the Anti-Human Carcinoma Monoclonal Antibody (mAb) NEO-201

por Tsang, Kwong Y., Fantini, Massimo, Zaki, Anjum, Mavroukakis, Sharon A., Morelli, Maria Pia, Annunziata, Christina M., Arlen, Philip M.
Publicado 2022

Preclinical Characterization of a Novel Monoclonal Antibody NEO-201 for the Treatment of Human Carcinomas

por Fantini, Massimo, David, Justin M., Saric, Olga, Dubeykovskiy, Alexander, Cui, Yongzhi, Mavroukakis, Sharon A., Bristol, Andrew, Annunziata, Christina M., Tsang, Kwong Y., Arlen, Philip M.
Publicado 2018

Impact of androgen deprivation therapy on the thymus and the production of naïve T-cells

por Madan, Ravi A, Frances, Hakim, Jochems, Caroline, Heery, Christopher R, O’Sullivan, Geraldine C, Singh, Harpreet, Surolia, Ira, Tsang, Kwong Y, Gress, Ronald, Schlom, Jeffery, Gulley, James L
Publicado 2013

Treatment with the IDO inhibitor INCB024360 increased lysis of human tumor cell targets by peptide-specific CTL

por Jochems, Caroline, Kwilas, Anna, Kim, Young-Seung, Brechbiel, Martin W, Fantini, Massimo, Metenou, Simon, Fernando, Romaine I, Kim, Peter S, Gameiro, Sofia, Hodge, James, Newton, Robert, Schlom, Jeffrey, Tsang, Kwong Y
Publicado 2015

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

por Hicks, Kristin C., Fantini, Massimo, Donahue, Renee N., Schwab, Angie, Knudson, Karin M., Tritsch, Sarah R., Jochems, Caroline, Clavijo, Paul E., Allen, Clint T., Hodge, James W., Tsang, Kwong Y., Schlom, Jeffrey, Gameiro, Sofia R.
Publicado 2018

Detection and Characterization of Circulating Tumour Cells from Frozen Peripheral Blood Mononuclear Cells

por Lu, David, Graf, Ryon P., Harvey, Melissa, Madan, Ravi A., Heery, Christopher, Marte, Jennifer, Beasley, Sharon, Tsang, Kwong Y., Krupa, Rachel, Louw, Jessica, Wahl, Justin, Bales, Natalee, Landers, Mark, Marrinucci, Dena, Schlom, Jeffrey, Gulley, James L., Dittamore, Ryan
Publicado 2015

Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer

por Zeligs, Kristen P., Morelli, Maria Pia, David, Justin M., Neuman, Monica, Hernandez, Lidia, Hewitt, Stephen, Ozaki, Michelle, Osei-Tutu, Akosua, Anderson, David, Andresson, Thorkell, Das, Sudipto, Lack, Justin, Abdelmaksoud, Abdalla, Fantini, Massimo, Arlen, Philip M., Tsang, Kwong Y., Annunziata, Christina M.
Publicado 2020

The IDO1 selective inhibitor epacadostat enhances dendritic cell immunogenicity and lytic ability of tumor antigen-specific T cells

por Jochems, Caroline, Fantini, Massimo, Fernando, Romaine I., Kwilas, Anna R., Donahue, Renee N., Lepone, Lauren M., Grenga, Italia, Kim, Young-Seung, Brechbiel, Martin W., Gulley, James L., Madan, Ravi A., Heery, Christopher R., Hodge, James W., Newton, Robert, Schlom, Jeffrey, Tsang, Kwong Y.
Publicado 2016

The generation and analysis of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

por Tsang, Kwong Y, Gabitzsch, Elizabeth S, Palena, Claudia, David, Justin M, Fantini, Massimo, Kwilas, Anna R, Rice, Adrian E, Latchman, Yvette, Hodge, James W, Jochems, Caroline, Fernando, Romaine I, Gulley, James, Madan, Ravi A, Heery, Christopher R, Balint, Joseph P, Jones, Frank R, Schlom, Jeffrey
Publicado 2015

First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors

por Cole, Christopher B., Morelli, Maria Pia, Fantini, Massimo, Miettinen, Markku, Fetsch, Patricia, Peer, Cody, Figg, William D., Yin, Tyler, Houston, Nicole, McCoy, Ann, Lipkowitz, Stanley, Zimmer, Alexandra, Lee, Jung-min, Pavelova, Miroslava, Villanueva, Erin N., Trewhitt, Kathryn, Solarz, B. Brooke, Fergusson, Maria, Mavroukakis, Sharon A., Zaki, Anjum, Tsang, Kwong Y., Arlen, Philip M., Annunziata, Christina M.
Publicado 2023

Correction: First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors

por Cole, Christopher B., Morelli, Maria Pia, Fantini, Massimo, Miettinen, Markku, Fetsch, Patricia, Peer, Cody, Figg, William D., Yin, Tyler, Houston, Nicole, McCoy, Ann, Lipkowitz, Stanley, Zimmer, Alexandra, Lee, Jung-min, Pavelova, Miroslava, Villanueva, Erin N., Trewhitt, Kathryn, Solarz, B. Brooke, Fergusson, Maria, Mavroukakis, Sharon A., Zaki, Anjum, Tsang, Kwong Y., Arlen, Philip M., Annunziata, Christina M.
Publicado 2023