Genome‐Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment

por Yang, Chunxue, Lee, Derek, Zhang, Misty Shuo, Tse, Aki Pui‐Wah, Wei, Lai, Bao, Macus Hao‐Ran, Wong, Bowie Po‐Yee, Chan, Cerise Yuen‐Ki, Yuen, Vincent Wai‐Hin, Chen, Yiling, Wong, Carmen Chak‐Lui
Publicado 2022

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma

por Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Di Cui, Jane, Lai, Robin Kit-Ho, Li, Lynna Lan, Koh, Hui-Yu, Tsang, Felice Ho-Ching, Wei, Larry Lai, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Publicado 2017

Switching of Pyruvate Kinase Isoform L to M2 Promotes Metabolic Reprogramming in Hepatocarcinogenesis

por Wong, Carmen Chak-Lui, Au, Sandy Leung-Kuen, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Chiu, David Kung-Chun, Wei, Larry Lai, Fan, Dorothy Ngo-Yin, Tsang, Felice Ho-Ching, Lo, Regina Cheuk-Lam, Wong, Chun-Ming, Ng, Irene Oi-Lin
Publicado 2014

Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

por Zhang, Misty Shuo, Cui, Jane Di, Lee, Derek, Yuen, Vincent Wai-Hin, Chiu, David Kung-Chun, Goh, Chi Ching, Cheu, Jacinth Wing-Sum, Tse, Aki Pui-Wah, Bao, Macus Hao-Ran, Wong, Bowie Po Yee, Chen, Carrie Yiling, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Publicado 2022

Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer

por Cheu, Jacinth Wing-Sum, Lee, Derek, Li, Qidong, Goh, Chi Ching, Bao, Macus Hao-Ran, Yuen, Vincent Wai-Hin, Zhang, Misty Shuo, Yang, Chunxue, Chan, Cerise Yuen-Ki, Tse, Aki Pui-Wah, Sit, Grace Fu-Wan, Liu, Cindy Xinqi, Ng, Irene Oi-Lin, Wong, Chun-Ming, Wong, Carmen Chak-Lui
Publicado 2023

Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer

por Tse, Aki Pui-Wah, Sze, Karen Man-Fong, Shea, Queenie Tsung-Kwan, Chiu, Elley Yung-Tuen, Tsang, Felice Ho-Ching, Chiu, David Kung-Chun, Zhang, Misty Shuo, Lee, Derek, Xu, Iris Ming-Jing, Chan, Cerise Yuen-Ki, Koh, Hui-Yu, Wong, Chun-Ming, Zheng, Yong-Ping, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Publicado 2018

CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma

por Chan, Cerise Yuen-Ki, Chiu, David Kung-Chun, Yuen, Vincent Wai-Hin, Law, Cheuk-Ting, Wong, Bowie Po-Yee, Thu, Kelsie Lynn, Cescon, David Ward, Soria-Bretones, Isabel, Cheu, Jacinth Wing-Sum, Lee, Derek, Tse, Aki Pui-Wah, Zhang, Misty Shuo, Tan, Kel Vin, Ng, Irene Oi-Lin, Khong, Pek-Lan, Yau, Thomas Chung-Cheung, Bray, Mark Robert, Mak, Tak Wah, Wong, Carmen Chak-Lui
Publicado 2022

Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development

por Cheu, Jacinth Wing-Sum, Chiu, David Kung-Chun, Kwan, Kenneth Kin-Leung, Yang, Chunxue, Yuen, Vincent Wai-Hin, Goh, Chi Ching, Chui, Noreen Nog-Qin, Shen, Wei, Law, Cheuk-Ting, Li, Qidong, Zhang, Misty Shuo, Bao, Macus Hao-Ran, Wong, Bowie Po-Yee, Chan, Cerise Yuen-Ki, Liu, Cindy Xinqi, Sit, Grace Fu-Wan, Ooi, Zher Yee, Deng, Haijing, Tse, Aki Pui-Wah, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Publicado 2023