Analyses of publicly available genomics resources define FGF-2-expressing bladder carcinomas as EMT-prone, proliferative tumors with low mutation rates and high expression of CTLA-...

por McNiel, Elizabeth A, Tsichlis, Philip N
Publicado 2017

Akt isoforms in the immune system

por Guerau-de-Arellano, Mireia, Piedra-Quintero, Zayda L., Tsichlis, Philip N.
Publicado 2022

AKT2 Loss Impairs BRAF-Mutant Melanoma Metastasis

por McRee, Siobhan K., Bayer, Abraham L., Pietruska, Jodie, Tsichlis, Philip N., Hinds, Philip W.
Publicado 2023

Prospective Evaluation of Effect of Metformin on Activation of AMP-activated Protein Kinase (AMPK) and Disease Control in a Sub-group Analysis of Patients with GI Malignancies

por Godara, Amandeep, Siddiqui, Nauman S., Hachem, Hilal, Tsichlis, Philip N., Martell, Robert E., Saif, Muhammad Wasif
Publicado 2020

The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Tra...

por Sourvinos, George, Morou, Antigoni, Sanidas, Ioannis, Codruta, Ignea, Ezell, Scott A., Doxaki, Christina, Kampranis, Sotirios C., Kottakis, Filippos, Tsichlis, Philip N.
Publicado 2014

Transcriptome Analysis of Human Endogenous Retroviruses at Locus-Specific Resolution in Non-Small Cell Lung Cancer

por La Ferlita, Alessandro, Distefano, Rosario, Alaimo, Salvatore, Beane, Joal D., Ferro, Alfredo, Croce, Carlo M., Tsichlis, Philip N., Pulvirenti, Alfredo, Nigita, Giovanni
Publicado 2022

PHENSIM: Phenotype Simulator

por Alaimo, Salvatore, Rapicavoli, Rosaria Valentina, Marceca, Gioacchino P., La Ferlita, Alessandro, Serebrennikova, Oksana B., Tsichlis, Philip N., Mishra, Bud, Pulvirenti, Alfredo, Ferro, Alfredo
Publicado 2021

Akt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model

por Saji, Motoyasu, Kim, Caroline S., Wang, Chaojie, Zhang, Xiaoli, Khanal, Tilak, Coombes, Kevin, La Perle, Krista, Cheng, Sheue-Yann, Tsichlis, Philip N., Ringel, Matthew D.
Publicado 2020

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality

por Orlacchio, Arturo, Stark, Aaron E., Foray, Claudia, Amari, Foued, Sheetz, Tyler, Reese, Erika, Tessari, Anna, La Perle, Krista, Palmieri, Dario, Tsichlis, Philip N., Coppola, Vincenzo
Publicado 2018

RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis

por La Ferlita, Alessandro, Alaimo, Salvatore, Di Bella, Sebastiano, Martorana, Emanuele, Laliotis, Georgios I., Bertoni, Francesco, Cascione, Luciano, Tsichlis, Philip N., Ferro, Alfredo, Bosotti, Roberta, Pulvirenti, Alfredo
Publicado 2021

TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells

por Kaiser, Frank, Cook, Dorthe, Papoutsopoulou, Stamatia, Rajsbaum, Ricardo, Wu, Xuemei, Yang, Huei-Ting, Grant, Susan, Ricciardi-Castagnoli, Paola, Tsichlis, Philip N., Ley, Steven C., O'Garra, Anne
Publicado 2009

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology

por Tsimberidou, Apostolia-Maria, Skliris, Antonis, Valentine, Alan, Shaw, Jamie, Hering, Ursula, Vo, Henry Hiep, Chan, Tung On, Armen, Roger S., Cottrell, Jeffrey R., Pan, Jen Q., Tsichlis, Philip N.
Publicado 2022

Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

por Chavdoula, Evangelia, Anastas, Vollter, Ferlita, Alessandro La, Aldana, Julian, Carota, Giuseppe, Spampinato, Mariarita, Soysal, Burak, Cosentini, Ilaria, Parashar, Sameer, Sircar, Anuvrat, Nigita, Giovanni, Sehgal, Lalit, Freitas, Michael A., Tsichlis, Philip N.
Publicado 2023

RETRACTED ARTICLE: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection

por Laliotis, Georgios I., Kenney, Adam D., Chavdoula, Evangelia, Orlacchio, Arturo, Kaba, Abdul, La Ferlita, Alessandro, Anastas, Vollter, Tsatsanis, Christos, Beane, Joal D., Sehgal, Lalit, Coppola, Vincenzo, Yount, Jacob S., Tsichlis, Philip N.
Publicado 2021

Retraction Note: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection

por Laliotis, Georgios I., Kenney, Adam D., Chavdoula, Evangelia, Orlacchio, Arturo, Kaba, Abdul, La Ferlita, Alessandro, Anastas, Vollter, Tsatsanis, Christos, Beane, Joal D., Sehgal, Lalit, Coppola, Vincenzo, Yount, Jacob S., Tsichlis, Philip N.
Publicado 2021

Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii

por Watford, Wendy T., Hissong, Bruce D., Durant, Lydia R., Yamane, Hidehiro, Muul, Linda M., Kanno, Yuka, Tato, Cristina M., Ramos, Haydeé L., Berger, Alan E., Mielke, Lisa, Pesu, Marko, Solomon, Benjamin, Frucht, David M., Paul, William E., Sher, Alan, Jankovic, Dragana, Tsichlis, Philip N., O'Shea, John J.
Publicado 2008

RETRACTED ARTICLE: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing

por Laliotis, Georgios I., Chavdoula, Evangelia, Paraskevopoulou, Maria D., Kaba, Abdul, La Ferlita, Alessandro, Singh, Satishkumar, Anastas, Vollter, Nair, Keith A., Orlacchio, Arturo, Taraslia, Vasiliki, Vlachos, Ioannis, Capece, Marina, Hatzigeorgiou, Artemis, Palmieri, Dario, Tsatsanis, Christos, Alaimo, Salvatore, Sehgal, Lalit, Carbone, David P., Coppola, Vincenzo, Tsichlis, Philip N.
Publicado 2021

Retraction Note: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing

por Laliotis, Georgios I., Chavdoula, Evangelia, Paraskevopoulou, Maria D., Kaba, Abdul, La Ferlita, Alessandro, Singh, Satishkumar, Anastas, Vollter, Nair, Keith A., Orlacchio, Arturo, Taraslia, Vasiliki, Vlachos, Ioannis, Capece, Marina, Hatzigeorgiou, Artemis, Palmieri, Dario, Tsatsanis, Christos, Alaimo, Salvatore, Sehgal, Lalit, Carbone, David P., Coppola, Vincenzo, Tsichlis, Philip N.
Publicado 2022

In vivo genome editing and organoid transplantation models of colorectal cancer

por Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye Malli, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Wu, Katherine, Oberli, Matthias, Sánchez-Rivera, Francisco, Park, Yoona, Liang, Xu, Eng, George, Taylor, Martin S., Azimi, Roxana, Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Sicinska, Ewa T., Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam, Tsichlis, Philip N., Lees, Jacqueline, Langer, Robert, Hynes, Richard O., Chen, Jianzhu, Bhutkar, Arjun J., Jacks, Tyler, Yilmaz, Ömer H.
Publicado 2017