Antibody-drug conjugates: recent advances in conjugation and linker chemistries

por Tsuchikama, Kyoji, An, Zhiqiang
Publicado 2016

Glutamic acid–valine–citrulline linkers ensure stability and efficacy of antibody–drug conjugates in mice

por Anami, Yasuaki, Yamazaki, Chisato M., Xiong, Wei, Gui, Xun, Zhang, Ningyan, An, Zhiqiang, Tsuchikama, Kyoji
Publicado 2018

Homogeneous antibody–angiopep 2 conjugates for effective brain targeting

por Anami, Yasuaki, Xiong, Wei, Yamaguchi, Aiko, Yamazaki, Chisato M., Zhang, Ningyan, An, Zhiqiang, Tsuchikama, Kyoji
Publicado 2022

Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model

por Zhao, Peng, Anami, Yasuaki, Gao, Peng, Fan, Xuejun, Li, Leike, Tsuchikama, Kyoji, Zhang, Ningyan, an, Zhiqiang
Publicado 2022

Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance

por Yamazaki, Chisato M., Yamaguchi, Aiko, Anami, Yasuaki, Xiong, Wei, Otani, Yoshihiro, Lee, Jangsoon, Ueno, Naoto T., Zhang, Ningyan, An, Zhiqiang, Tsuchikama, Kyoji
Publicado 2021

Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors

por Anami, Yasuaki, Otani, Yoshihiro, Xiong, Wei, Ha, Summer Y.Y., Yamaguchi, Aiko, Rivera-Caraballo, Kimberly A., Zhang, Ningyan, An, Zhiqiang, Kaur, Balveen, Tsuchikama, Kyoji
Publicado 2022