PKC-Theta in Regulatory and Effector T-cell Functions

por Brezar, Vedran, Tu, Wen Juan, Seddiki, Nabila
Publicado 2015

Multi-layered epigenetic mechanisms contribute to transcriptional memory in T lymphocytes

por Dunn, Jennifer, McCuaig, Robert, Tu, Wen Juan, Hardy, Kristine, Rao, Sudha
Publicado 2015

The UII/UT System Mediates Upregulation of Proinflammatory Cytokines through p38 MAPK and NF-κB Pathways in LPS-Stimulated Kupffer Cells

por Liu, Liang Ming, Liang, Dong Yu, Ye, Chang Gen, Tu, Wen Juan, Zhu, Tong
Publicado 2015

Diffusion tensor imaging assesses white matter injury in neonates with hypoxic-ischemic encephalopathy

por Li, Hong-xin, Feng, Xing, Wang, Qian, Dong, Xuan, Yu, Min, Tu, Wen-juan
Publicado 2017

Epitherapy and immune checkpoint blockade: using epigenetic reinvigoration of exhausted and dysfunctional T cells to reimburse immunotherapy response

por McGoverne, Isabella, Dunn, Jenny, Batham, Jacob, Tu, Wen Juan, Chrisp, Jeremy, Rao, Sudha
Publicado 2020

Resting-state network complexity and magnitude changes in neonates with severe hypoxic ischemic encephalopathy

por Li, Hong-Xin, Yu, Min, Zheng, Ai-Bin, Zhang, Qin-Fen, Hua, Guo-Wei, Tu, Wen-Juan, Zhang, Li-Chi
Publicado 2019

Cardioprotective Effects of Genistin in Rat Myocardial Ischemia-Reperfusion Injury Studies by Regulation of P2X7/NF-κB Pathway

por Gu, Meng, Zheng, Ai-bin, Jin, Jing, Cui, Yue, Zhang, Ning, Che, Zhi-ping, Wang, Yan, Zhan, Jie, Tu, Wen-juan
Publicado 2016

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer

por Tan, Abel H. Y., Tu, WenJuan, McCuaig, Robert, Hardy, Kristine, Donovan, Thomasina, Tsimbalyuk, Sofiya, Forwood, Jade K., Rao, Sudha
Publicado 2019

IRF3 is an important molecule in the UII/UT system and mediates immune inflammatory injury in acute liver failure

por Liu, Liang-ming, Tu, Wen-juan, Zhu, Tong, Wang, Xiao-ting, Tan, Zhi-li, Zhong, Huan, Gao, De-yong, Liang, Dong-yu
Publicado 2016

A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED)

por Prasanna, Thiru, Malik, Laeeq, McCuaig, Robert D., Tu, Wen Juan, Wu, Fan, Lim, Pek Siew, Tan, Abel H. Y., Dahlstrom, Jane E., Clingan, Philip, Moylan, Eugene, Chrisp, Jeremy, Fuller, David, Rao, Sudha, Yip, Desmond
Publicado 2022

Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells

por Tu, Wen Juan, Hardy, Kristine, Sutton, Christopher R., McCuaig, Robert, Li, Jasmine, Dunn, Jenny, Tan, Abel, Brezar, Vedran, Morris, Melanie, Denyer, Gareth, Lee, Sau Kuen, Turner, Stephen J., Seddiki, Nabila, Smith, Corey, Khanna, Rajiv, Rao, Sudha
Publicado 2017

Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch

por Tu, Wen Juan, McCuaig, Robert D., Tan, Abel H. Y., Hardy, Kristine, Seddiki, Nabila, Ali, Sayed, Dahlstrom, Jane E., Bean, Elaine G., Dunn, Jenny, Forwood, Jade, Tsimbalyuk, Sofia, Smith, Kate, Yip, Desmond, Malik, Laeeq, Prasanna, Thiru, Milburn, Peter, Rao, Sudha
Publicado 2020

Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

por Tu, Wen Juan, McCuaig, Robert D., Melino, Michelle, Rawle, Daniel J., Le, Thuy T., Yan, Kexin, Suhrbier, Andreas, Johnston, Rebecca L., Koufariotis, Lambros T., Waddell, Nicola, Cross, Emily M., Tsimbalyuk, Sofiya, Bain, Amanda, Ahern, Elizabeth, Collinson, Natasha, Phipps, Simon, Forwood, Jade K., Seddiki, Nabila, Rao, Sudha
Publicado 2021

Author Correction: Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

por Tu, Wen Juan, McCuaig, Robert D., Melino, Michelle, Rawle, Daniel J., Le, Thuy T., Yan, Kexin, Suhrbier, Andreas, Johnston, Rebecca L., Koufariotis, Lambros T., Waddell, Nicola, Cross, Emily M., Tsimbalyuk, Sofiya, Bain, Amanda, Ahern, Elizabeth, Collinson, Natasha, Phipps, Simon, Forwood, Jade K., Seddiki, Nabila, Rao, Sudha
Publicado 2021

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4(+) T cells through p65 and H2B phosphorylation

por Li, Jasmine, Hardy, Kristine, Phetsouphanh, Chan, Tu, Wen Juan, Sutcliffe, Elissa L., McCuaig, Robert, Sutton, Christopher R., Zafar, Anjum, Munier, C. Mee Ling, Zaunders, John J., Xu, Yin, Theodoratos, Angelo, Tan, Abel, Lim, Pek Siew, Knaute, Tobias, Masch, Antonia, Zerweck, Johannes, Brezar, Vedran, Milburn, Peter J., Dunn, Jenny, Casarotto, Marco G., Turner, Stephen J., Seddiki, Nabila, Kelleher, Anthony D., Rao, Sudha
Publicado 2016

Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8(+) T Cells in Immunotherapy-Resistant...

por Dunn, Jenny, McCuaig, Robert D., Tan, Abel H. Y., Tu, Wen Juan, Wu, Fan, Wagstaff, Kylie M., Zafar, Anjum, Ali, Sayed, Diwakar, Himanshu, Dahlstrom, Jane E., Bean, Elaine G., Forwood, Jade K., Tsimbalyuk, Sofiya, Cross, Emily M., Hardy, Kristine, Bain, Amanda L., Ahern, Elizabeth, Dolcetti, Riccardo, Mazzieri, Roberta, Yip, Desmond, Eastgate, Melissa, Malik, Laeeq, Milburn, Peter, Jans, David A., Rao, Sudha
Publicado 2022

In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting

por Tu, Wen Juan, Melino, Michelle, Dunn, Jenny, McCuaig, Robert D., Bielefeldt-Ohmann, Helle, Tsimbalyuk, Sofiya, Forwood, Jade K., Ahuja, Taniya, Vandermeide, John, Tan, Xiao, Tran, Minh, Nguyen, Quan, Zhang, Liang, Nam, Andy, Pan, Liuliu, Liang, Yan, Smith, Corey, Lineburg, Katie, Nguyen, Tam H., Sng, Julian D. J., Tong, Zhen Wei Marcus, Chew, Keng Yih, Short, Kirsty R., Le Grand, Roger, Seddiki, Nabila, Rao, Sudha
Publicado 2023