Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia

por Shibuya, Ayako, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado 2013

Pregnane-X-Receptor Controls Hepatic Glucuronidation During Pregnancy and Neonatal Development in Humanized UGT1 Mice

por Chen, Shujuan, Yueh, Mei-Fei, Evans, Ronald M, Tukey, Robert H
Publicado 2012

Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia

por Aoshima, Naoya, Fujie, Yoshiko, Itoh, Tomoo, Tukey, Robert H., Fujiwara, Ryoichi
Publicado 2014

Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes

por Kutsuno, Yuki, Sumida, Kyohei, Itoh, Tomoo, Tukey, Robert H, Fujiwara, Ryoichi
Publicado 2013

Severe neonatal hyperbilirubinemia in Crigler‐Najjar syndrome model mice can be reversed with zinc protoporphyrin

por Fujiwara, Ryoichi, Mitsugi, Ryo, Uemura, Asuka, Itoh, Tomoo, Tukey, Robert H.
Publicado 2017

Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha

por Yueh, Mei-Fei, Li, Tao, Evans, Ronald M., Hammock, Bruce, Tukey, Robert H.
Publicado 2012

Isothiocyanates induce UGT1A1 in humanized UGT1 mice in a CAR dependent fashion that is highly dependent upon oxidative stress

por Yoda, Emiko, Paszek, Miles, Konopnicki, Camille, Fujiwara, Ryoichi, Chen, Shujuan, Tukey, Robert H.
Publicado 2017

Reduction of p53 by Knockdown of the UGT1 Locus in Colon Epithelial Cells Causes an Increase in Tumorigenesis

por Liu, Miao, Chen, Shujuan, Yueh, Mei-Fei, Wang, Guangji, Hao, Haiping, Tukey, Robert H.
Publicado 2015

Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice

por Weber, André A., Yang, Xiaojing, Mennillo, Elvira, Ding, Jeffrey, Watrous, Jeramie D., Jain, Mohit, Chen, Shujuan, Karin, Michael, Tukey, Robert H.
Publicado 2022

Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR

por Yang, Xiaojing, Weber, André A., Mennillo, Elvira, Paszek, Miles, Wong, Samantha, Le, Sabrina, Teo, Jia Ying Ashley, Chang, Max, Benner, Christopher W., Tukey, Robert H., Chen, Shujuan
Publicado 2023

The NIEHS Superfund Research Program: 25 Years of Translational Research for Public Health

por Landrigan, Philip J., Wright, Robert O., Cordero, Jose F., Eaton, David L., Goldstein, Bernard D., Hennig, Bernhard, Maier, Raina M., Ozonoff, David M., Smith, Martyn T., Tukey, Robert H.
Publicado 2015

Effects of Early Life Oral Arsenic Exposure on Intestinal Tract Development and Lipid Homeostasis in Neonatal Mice: Implications for NAFLD Development

por Yang, Xiaojing, Weber, André A., Mennillo, Elvira, Secrest, Patrick, Chang, Max, Wong, Samantha, Le, Sabrina, Liu, Junlai, Benner, Christopher W., Karin, Michael, Gordts, Philip L.S.M., Tukey, Robert H., Chen, Shujuan
Publicado 2023

Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

por van der Schoor, Lori W. E., Verkade, Henkjan J., Bertolini, Anna, de Wit, Sanne, Mennillo, Elvira, Rettenmeier, Eva, Weber, André A., Havinga, Rick, Valášková, Petra, Jašprová, Jana, Struik, Dicky, Bloks, Vincent W., Chen, Shujuan, Schreuder, Andrea B., Vítek, Libor, Tukey, Robert H., Jonker, Johan W.
Publicado 2021