LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels

por Leinonen, Jaakko T., Chen, Yu-Chia, Pennonen, Jana, Lehtonen, Leevi, Junna, Nella, Tukiainen, Taru, Panula, Pertti, Widén, Elisabeth
Publicado 2019

High-resolution population-specific recombination rates and their effect on phasing and genotype imputation

por Hassan, Shabbeer, Surakka, Ida, Taskinen, Marja-Riitta, Salomaa, Veikko, Palotie, Aarno, Wessman, Maija, Tukiainen, Taru, Pirinen, Matti, Palta, Priit, Ripatti, Samuli
Publicado 2020

Lipidome‐ and Genome‐Wide Study to Understand Sex Differences in Circulatory Lipids

por Tabassum, Rubina, Ruotsalainen, Sanni, Ottensmann, Linda, Gerl, Mathias J., Klose, Christian, Tukiainen, Taru, Pirinen, Matti, Simons, Kai, Widén, Elisabeth, Ripatti, Samuli
Publicado 2022

Genome-wide association study of varicose veins identifies a protective missense variant in GJD3 enriched in the Finnish population

por Helkkula, Pyry, Hassan, Shabbeer, Saarentaus, Elmo, Vartiainen, Emilia, Ruotsalainen, Sanni, Leinonen, Jaakko T., Palotie, Aarno, Karjalainen, Juha, Kurki, Mitja, Ripatti, Samuli, Tukiainen, Taru
Publicado 2023

A Differential Network Approach to Exploring Differences between Biological States: An Application to Prediabetes

por Valcárcel, Beatriz, Würtz, Peter, Seich al Basatena, Nafisa-Katrin, Tukiainen, Taru, Kangas, Antti J., Soininen, Pasi, Järvelin, Marjo-Riitta, Ala-Korpela, Mika, Ebbels, Timothy M., de Iorio, Maria
Publicado 2011

Genetic analyses implicate complex links between adult testosterone levels and health and disease

por Leinonen, Jaakko T., Mars, Nina, Lehtonen, Leevi E., Ahola-Olli, Ari, Ruotsalainen, Sanni, Lehtimäki, Terho, Kähönen, Mika, Raitakari, Olli, Piltonen, Terhi, Daly, Mark, Tuomi, Tiinamaija, Ripatti, Samuli, Pirinen, Matti, Tukiainen, Taru
Publicado 2023

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems

por Shu, Le, Zhao, Yuqi, Kurt, Zeyneb, Byars, Sean Geoffrey, Tukiainen, Taru, Kettunen, Johannes, Orozco, Luz D., Pellegrini, Matteo, Lusis, Aldons J., Ripatti, Samuli, Zhang, Bin, Inouye, Michael, Mäkinen, Ville-Petteri, Yang, Xia
Publicado 2016

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population

por Salo, Perttu P., Havulinna, Aki S., Tukiainen, Taru, Raitakari, Olli, Lehtimäki, Terho, Kähönen, Mika, Kettunen, Johannes, Männikkö, Minna, Eriksson, Johan G., Jula, Antti, Blankenberg, Stefan, Zeller, Tanja, Salomaa, Veikko, Kristiansson, Kati, Perola, Markus
Publicado 2017

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults

por Würtz, Peter, Mäkinen, Ville-Petteri, Soininen, Pasi, Kangas, Antti J., Tukiainen, Taru, Kettunen, Johannes, Savolainen, Markku J., Tammelin, Tuija, Viikari, Jorma S., Rönnemaa, Tapani, Kähönen, Mika, Lehtimäki, Terho, Ripatti, Samuli, Raitakari, Olli T., Järvelin, Marjo-Riitta, Ala-Korpela, Mika
Publicado 2012

Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation

por Tukiainen, Taru, Pirinen, Matti, Sarin, Antti-Pekka, Ladenvall, Claes, Kettunen, Johannes, Lehtimäki, Terho, Lokki, Marja-Liisa, Perola, Markus, Sinisalo, Juha, Vlachopoulou, Efthymia, Eriksson, Johan G., Groop, Leif, Jula, Antti, Järvelin, Marjo-Riitta, Raitakari, Olli T., Salomaa, Veikko, Ripatti, Samuli
Publicado 2014

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

por Ripatti, Pietari, Rämö, Joel T., Mars, Nina J., Fu, Yu, Lin, Jake, Söderlund, Sanni, Benner, Christian, Surakka, Ida, Kiiskinen, Tuomo, Havulinna, Aki S., Palta, Priit, Freimer, Nelson B., Widén, Elisabeth, Salomaa, Veikko, Tukiainen, Taru, Pirinen, Matti, Palotie, Aarno, Taskinen, Marja-Riitta, Ripatti, Samuli
Publicado 2020

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

por Nowak, Christoph, Salihovic, Samira, Ganna, Andrea, Brandmaier, Stefan, Tukiainen, Taru, Broeckling, Corey D., Magnusson, Patrik K., Prenni, Jessica E., Wang-Sattler, Rui, Peters, Annette, Strauch, Konstantin, Meitinger, Thomas, Giedraitis, Vilmantas, Ärnlöv, Johan, Berne, Christian, Gieger, Christian, Ripatti, Samuli, Lind, Lars, Pedersen, Nancy L., Sundström, Johan, Ingelsson, Erik, Fall, Tove
Publicado 2016

Correction: Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

por Nowak, Christoph, Salihovic, Samira, Ganna, Andrea, Brandmaier, Stefan, Tukiainen, Taru, Broeckling, Corey D., Magnusson, Patrik K., Prenni, Jessica E., Wang-Sattler, Rui, Peters, Annette, Strauch, Konstantin, Meitinger, Thomas, Giedraitis, Vilmantas, Ärnlöv, Johan, Berne, Christian, Gieger, Christian, Ripatti, Samuli, Lind, Lars, Pedersen, Nancy L., Sundström, Johan, Ingelsson, Erik, Fall, Tove
Publicado 2017

Landscape of X chromosome inactivation across human tissues

por Tukiainen, Taru, Villani, Alexandra-Chloé, Yen, Angela, Rivas, Manuel A., Marshall, Jamie L., Satija, Rahul, Aguirre, Matt, Gauthier, Laura, Fleharty, Mark, Kirby, Andrew, Cummings, Beryl B., Castel, Stephane E., Karczewski, Konrad J., Aguet, François, Byrnes, Andrea, Lappalainen, Tuuli, Regev, Aviv, Ardlie, Kristin G., Hacohen, Nir, MacArthur, Daniel G.
Publicado 2017

The landscape of genomic imprinting across diverse adult human tissues

por Baran, Yael, Subramaniam, Meena, Biton, Anne, Tukiainen, Taru, Tsang, Emily K., Rivas, Manuel A., Pirinen, Matti, Gutierrez-Arcelus, Maria, Smith, Kevin S., Kukurba, Kim R., Zhang, Rui, Eng, Celeste, Torgerson, Dara G., Urbanek, Cydney, Li, Jin Billy, Rodriguez-Santana, Jose R., Burchard, Esteban G., Seibold, Max A., MacArthur, Daniel G., Montgomery, Stephen B., Zaitlen, Noah A., Lappalainen, Tuuli
Publicado 2015

Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI

por van der Kolk, Birgitta W., Saari, Sina, Lovric, Alen, Arif, Muhammad, Alvarez, Marcus, Ko, Arthur, Miao, Zong, Sahebekhtiari, Navid, Muniandy, Maheswary, Heinonen, Sini, Oghabian, Ali, Jokinen, Riikka, Jukarainen, Sakari, Hakkarainen, Antti, Lundbom, Jesper, Kuula, Juho, Groop, Per-Henrik, Tukiainen, Taru, Lundbom, Nina, Rissanen, Aila, Kaprio, Jaakko, Williams, Evan G., Zamboni, Nicola, Mardinoglu, Adil, Pajukanta, Päivi, Pietiläinen, Kirsi H.
Publicado 2021

WGS and RNA Studies Diagnose Noncoding DMD Variants in Males With High Creatine Kinase

por Waddell, Leigh B., Bryen, Samantha J., Cummings, Beryl B., Bournazos, Adam, Evesson, Frances J., Joshi, Himanshu, Marshall, Jamie L., Tukiainen, Taru, Valkanas, Elise, Weisburd, Ben, Sadedin, Simon, Davis, Mark R., Faiz, Fathimath, Gooding, Rebecca, Sandaradura, Sarah A., O'Grady, Gina L., Tchan, Michel C., Mowat, David R., Oates, Emily C., Farrar, Michelle A., Sampaio, Hugo, Ma, Alan, Neas, Katherine, Wang, Min-Xia, Charlton, Amanda, Chan, Charles, Kenwright, Diane N., Graf, Nicole, Arbuckle, Susan, Clarke, Nigel F., MacArthur, Daniel G., Jones, Kristi J., Lek, Monkol, Cooper, Sandra T.
Publicado 2021

Population analyses of mosaic X chromosome loss identify genetic drivers and widespread signatures of cellular selection

por Liu, Aoxing, Genovese, Giulio, Zhao, Yajie, Pirinen, Matti, Zekavat, Maryam M., Kentistou, Katherine, Yang, Zhiyu, Yu, Kai, Vlasschaert, Caitlyn, Liu, Xiaoxi, Brown, Derek W., Hudjashov, Georgi, Gorman, Bryan, Dennis, Joe, Zhou, Weiyin, Momozawa, Yukihide, Pyarajan, Saiju, Tuzov, Vlad, Pajuste, Fanny-Dhelia, Aavikko, Mervi, Sipilä, Timo P., Ghazal, Awaisa, Huang, Wen-Yi, Freedman, Neal, Song, Lei, Gardner, Eugene J., Sankaran, Vijay G., Palotie, Aarno, Ollila, Hanna M., Tukiainen, Taru, Chanock, Stephen J., Mägi, Reedik, Natarajan, Pradeep, Daly, Mark J., Bick, Alexander, McCarroll, Steven A., Terao, Chikashi, Loh, Po-Ru, Ganna, Andrea, Perry, John R.B., Machiela, Mitchell J.
Publicado 2023

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

por Kettunen, Johannes, Demirkan, Ayşe, Würtz, Peter, Draisma, Harmen H.M., Haller, Toomas, Rawal, Rajesh, Vaarhorst, Anika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Pirinen, Matti, Pool, René, Sarin, Antti-Pekka, Soininen, Pasi, Tukiainen, Taru, Wang, Qin, Tiainen, Mika, Tynkkynen, Tuulia, Amin, Najaf, Zeller, Tanja, Beekman, Marian, Deelen, Joris, van Dijk, Ko Willems, Esko, Tõnu, Hottenga, Jouke-Jan, van Leeuwen, Elisabeth M, Lehtimäki, Terho, Mihailov, Evelin, Rose, Richard J., de Craen, Anton J.M., Gieger, Christian, Kähönen, Mika, Perola, Markus, Blankenberg, Stefan, Savolainen, Markku J., Verhoeven, Aswin, Viikari, Jorma, Willemsen, Gonneke, Boomsma, Dorret I., van Duijn, Cornelia M., Eriksson, Johan, Jula, Antti, Järvelin, Marjo-Riitta, Kaprio, Jaakko, Metspalu, Andres, Raitakari, Olli, Salomaa, Veikko, Slagboom, P. Eline, Waldenberger, Melanie, Ripatti, Samuli, Ala-Korpela, Mika
Publicado 2016

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

por Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Publicado 2016