CRISPR-Cas9-based mutagenesis frequently provokes on-target mRNA misregulation

por Tuladhar, Rubina, Yeu, Yunku, Tyler Piazza, John, Tan, Zhen, Rene Clemenceau, Jean, Wu, Xiaofeng, Barrett, Quinn, Herbert, Jeremiah, Mathews, David H., Kim, James, Hyun Hwang, Tae, Lum, Lawrence
Publicado 2019

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumor suppressor

por Wu, Xiaofeng, Zhang, Li-shu, Toombs, Jason, Kuo, Yi-Chun, Piazza, John Tyler, Tuladhar, Rubina, Barrett, Quinn, Fan, Chih-wei, Zhang, Xuewu, Walensky, Loren D., Kool, Marcel, Cheng, Steven Y., Brekken, Rolf, Opferman, Joseph T., Green, Douglas R., Moldoveanu, Tudor, Lum, Lawrence
Publicado 2017

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9

por Zhang, Li-shu, Kang, Xunlei, Lu, Jianming, Zhang, Yuannyu, Wu, Xiaofeng, Wu, Guojin, Zheng, Junke, Tuladhar, Rubina, Shi, Heping, Wang, Qiaoling, Morlock, Lorraine, Yao, Huiyu, Huang, Lily Jun-shen, Maire, Pascal, Kim, James, Williams, Noelle, Xu, Jian, Chen, Chuo, Zhang, Cheng Cheng, Lum, Lawrence
Publicado 2018