Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity

por Tumbale, Percy, Williams, Jessica S., Schellenberg, Matthew J., Kunkel, Thomas A., Williams, R. Scott
Publicado 2013

High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication

por Williams, Jessica S., Tumbale, Percy P., Arana, Mercedes E., Rana, Julian A., Williams, R. Scott, Kunkel, Thomas A.
Publicado 2021

Structure of an Aprataxin–DNA complex with insights into AOA1 Neurodegenerative Disease

por Tumbale, Percy, Appel, C. Denise, Kraehenbuehl, Rolf, Robertson, Patrick D., Williams, Jessica S., Krahn, Joe, Ahel, Ivan, Williams, R. Scott
Publicado 2011

Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen

por Thiyagarajan, Nethaji, Pham, Tram T. K., Stinson, Brittany, Sundriyal, Amit, Tumbale, Percy, Lizotte-Waniewski, Michelle, Brew, Keith, Acharya, K. Ravi
Publicado 2012

Two-tiered enforcement of high-fidelity DNA ligation

por Tumbale, Percy P., Jurkiw, Thomas J., Schellenberg, Matthew J., Riccio, Amanda A., O’Brien, Patrick J, Williams, R. Scott
Publicado 2019

Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis

por Kaminski, Andrea M., Tumbale, Percy P., Schellenberg, Matthew J., Williams, R. Scott, Williams, Jason G., Kunkel, Thomas A., Pedersen, Lars C., Bebenek, Katarzyna
Publicado 2018

Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease

por Tumbale, Percy, Schellenberg, Matthew J, Mueller, Geoffrey A, Fairweather, Emma, Watson, Mandy, Little, Jessica N, Krahn, Juno, Waddell, Ian, London, Robert E, Williams, R Scott
Publicado 2018