Automated Recognition of Plasmodium falciparum Parasites from Portable Blood Levitation Imaging

por Deshmukh, Shreya S., Byaruhanga, Oswald, Tumwebaze, Patrick, Akin, Demir, Greenhouse, Bryan, Egan, Elizabeth S., Demirci, Utkan
Publicado 2022

Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum

por Duvalsaint, Marvin, Conrad, Melissa D., Tukwasibwe, Stephen, Tumwebaze, Patrick K., Legac, Jennifer, Cooper, Roland A., Rosenthal, Philip J.
Publicado 2021

Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda

por Tukwasibwe, Stephen, Tumwebaze, Patrick, Conrad, Melissa, Arinaitwe, Emmanuel, Kamya, Moses R., Dorsey, Grant, Nsobya, Samuel L., Greenhouse, Bryan, Rosenthal, Philip J.
Publicado 2017

Mass screening tools for glucose-6-phosphate dehydrogenase deficiency: validation of the WST8/1 -methoxy-PMS enzymatic assay in a highly malaria-endemic area in Uganda

por De Niz, Mariana, Eziefula, Alice C, Maiteki-Sebuguzi, Catherine, Gonahasa, Sam, DiLiberto, Deborah, Tumwebaze, Patrick, Staedke, Sarah G, Drakeley, Chris J
Publicado 2012

Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda

por Nankoberanyi, Sheila, Mbogo, George W, LeClair, Norbert P, Conrad, Melissa D, Tumwebaze, Patrick, Tukwasibwe, Stephen, Kamya, Moses R, Tappero, Jordan, Nsobya, Samuel L, Rosenthal, Philip J
Publicado 2014

Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda

por De Niz, Mariana, Eziefula, Alice C, Othieno, Lucas, Mbabazi, Edith, Nabukeera, Damalie, Ssemmondo, Emmanuel, Gonahasa, Samuel, Tumwebaze, Patrick, DiLiberto, Deborah, Maiteki-Sebuguzi, Catherine, Staedke, Sarah G, Drakeley, Chris
Publicado 2013

Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda

por Tumwebaze, Patrick K., Conrad, Melissa D., Okitwi, Martin, Orena, Stephen, Byaruhanga, Oswald, Katairo, Thomas, Legac, Jennifer, Garg, Shreeya, Giesbrecht, David, Smith, Sawyer R., Ceja, Frida G., Nsobya, Samuel L., Bailey, Jeffrey A., Cooper, Roland A., Rosenthal, Philip J.
Publicado 2022

Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study

por Tumwebaze, Patrick K, Katairo, Thomas, Okitwi, Martin, Byaruhanga, Oswald, Orena, Stephen, Asua, Victor, Duvalsaint, Marvin, Legac, Jennifer, Chelebieva, Sevil, Ceja, Frida G, Rasmussen, Stephanie A, Conrad, Melissa D, Nsobya, Samuel L, Aydemir, Ozkan, Bailey, Jeffrey A, Bayles, Brett R, Rosenthal, Philip J, Cooper, Roland A
Publicado 2021

Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline

por Kreutzfeld, Oriana, Tumwebaze, Patrick K., Okitwi, Martin, Orena, Stephen, Byaruhanga, Oswald, Katairo, Thomas, Conrad, Melissa D., Rasmussen, Stephanie A., Legac, Jennifer, Aydemir, Ozkan, Giesbrecht, David, Forte, Barbara, Campbell, Peter, Smith, Alasdair, Kano, Hiroki, Nsobya, Samuel L., Blasco, Benjamin, Duffey, Maelle, Bailey, Jeffrey A., Cooper, Roland A., Rosenthal, Philip J.
Publicado 2023

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

por Kirkman, Laura A., Zhan, Wenhu, Visone, Joseph, Dziedziech, Alexis, Singh, Pradeep K., Fan, Hao, Tong, Xinran, Bruzual, Igor, Hara, Ryoma, Kawasaki, Masanori, Imaeda, Toshihiro, Okamoto, Rei, Sato, Kenjiro, Michino, Mayako, Alvaro, Elena Fernandez, Guiang, Liselle F., Sanz, Laura, Mota, Daniel J., Govindasamy, Kavitha, Wang, Rong, Ling, Yan, Tumwebaze, Patrick K., Sukenick, George, Shi, Lei, Vendome, Jeremie, Bhanot, Purnima, Rosenthal, Philip J., Aso, Kazuyoshi, Foley, Michael A., Cooper, Roland A., Kafsack, Bjorn, Doggett, J. Stone, Nathan, Carl F., Lin, Gang
Publicado 2018

The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC

por Verity, Robert, Aydemir, Ozkan, Brazeau, Nicholas F., Watson, Oliver J., Hathaway, Nicholas J., Mwandagalirwa, Melchior Kashamuka, Marsh, Patrick W., Thwai, Kyaw, Fulton, Travis, Denton, Madeline, Morgan, Andrew P., Parr, Jonathan B., Tumwebaze, Patrick K., Conrad, Melissa, Rosenthal, Philip J., Ishengoma, Deus S., Ngondi, Jeremiah, Gutman, Julie, Mulenga, Modest, Norris, Douglas E., Moss, William J., Mensah, Benedicta A., Myers-Hansen, James L., Ghansah, Anita, Tshefu, Antoinette K., Ghani, Azra C., Meshnick, Steven R., Bailey, Jeffrey A., Juliano, Jonathan J.
Publicado 2020

Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncompl...

por Taft, Benjamin R., Yokokawa, Fumiaki, Kirrane, Tom, Mata, Anne-Catherine, Huang, Richard, Blaquiere, Nicole, Waldron, Grace, Zou, Bin, Simon, Oliver, Vankadara, Subramanyam, Chan, Wai Ling, Ding, Mei, Sim, Sandra, Straimer, Judith, Guiguemde, Armand, Lakshminarayana, Suresh B., Jain, Jay Prakash, Bodenreider, Christophe, Thompson, Christopher, Lanshoeft, Christian, Shu, Wei, Fang, Eric, Qumber, Jafri, Chan, Katherine, Pei, Luying, Chen, Yen-Liang, Schulz, Hanna, Lim, Jessie, Abas, Siti Nurdiana, Ang, Xiaoman, Liu, Yugang, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Gamo, Francisco Javier, Crespo-Fernandez, Benigno, Rosenthal, Philip J., Cooper, Roland A., Tumwebaze, Patrick, Aguiar, Anna Caroline Campos, Campo, Brice, Campbell, Simon, Wagner, Jürgen, Diagana, Thierry T., Sarko, Christopher
Publicado 2022

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

por de Vries, Laura E., Jansen, Patrick A. M., Barcelo, Catalina, Munro, Justin, Verhoef, Julie M. J., Pasaje, Charisse Flerida A., Rubiano, Kelly, Striepen, Josefine, Abla, Nada, Berning, Luuk, Bolscher, Judith M., Demarta-Gatsi, Claudia, Henderson, Rob W. M., Huijs, Tonnie, Koolen, Karin M. J., Tumwebaze, Patrick K., Yeo, Tomas, Aguiar, Anna C. C., Angulo-Barturen, Iñigo, Churchyard, Alisje, Baum, Jake, Fernández, Benigno Crespo, Fuchs, Aline, Gamo, Francisco-Javier, Guido, Rafael V. C., Jiménez-Diaz, María Belén, Pereira, Dhelio B., Rochford, Rosemary, Roesch, Camille, Sanz, Laura M., Trevitt, Graham, Witkowski, Benoit, Wittlin, Sergio, Cooper, Roland A., Rosenthal, Philip J., Sauerwein, Robert W., Schalkwijk, Joost, Hermkens, Pedro H. H., Bonnert, Roger V., Campo, Brice, Fidock, David A., Llinás, Manuel, Niles, Jacquin C., Kooij, Taco W. A., Dechering, Koen J.
Publicado 2022