Dexamethasone Downregulates Autophagy through Accelerated Turn-Over of the Ulk-1 Complex in a Trabecular Meshwork Cells Strain: Insights on Steroid-Induced Glaucoma Pathogenesis

por Sbardella, Diego, Tundo, Grazia Raffaella, Coletta, Massimo, Manni, Gianluca, Oddone, Francesco
Publicado 2021

Nitrite Reductase Activity of Ferrous Nitrobindins: A Comparative Study

por De Simone, Giovanna, di Masi, Alessandra, Tundo, Grazia R., Coletta, Massimo, Ascenzi, Paolo
Publicado 2023

Somatostatin Modulates Insulin-Degrading-Enzyme Metabolism: Implications for the Regulation of Microglia Activity in AD

por Tundo, Grazia, Ciaccio, Chiara, Sbardella, Diego, Boraso, Mariaserena, Viviani, Barbara, Coletta, Massimiliano, Marini, Stefano
Publicado 2012

Nitrosylation Mechanisms of Mycobacterium tuberculosis and Campylobacter jejuni Truncated Hemoglobins N, O, and P

por Ascenzi, Paolo, di Masi, Alessandra, Tundo, Grazia R., Pesce, Alessandra, Visca, Paolo, Coletta, Massimo
Publicado 2014

At the Cutting Edge against Cancer: A Perspective on Immunoproteasome and Immune Checkpoints Modulation as a Potential Therapeutic Intervention

por Tundo, Grazia R., Sbardella, Diego, Oddone, Francesco, Kudriaeva, Anna A., Lacal, Pedro M., Belogurov, Alexey A., Graziani, Grazia, Marini, Stefano
Publicado 2021

Proteasome Activity Is Affected by Fluctuations in Insulin-Degrading Enzyme Distribution

por Sbardella, Diego, Tundo, Grazia Raffaella, Sciandra, Francesca, Bozzi, Manuela, Gioia, Magda, Ciaccio, Chiara, Tarantino, Umberto, Brancaccio, Andrea, Coletta, Massimo, Marini, Stefano
Publicado 2015

The Insulin-Degrading Enzyme from Structure to Allosteric Modulation: New Perspectives for Drug Design

por Tundo, Grazia Raffaella, Grasso, Giuseppe, Persico, Marco, Tkachuk, Oleh, Bellia, Francesco, Bocedi, Alessio, Marini, Stefano, Parravano, Mariacristina, Graziani, Grazia, Fattorusso, Caterina, Sbardella, Diego
Publicado 2023

Functional and Spectroscopic Characterization of Chlamydomonas reinhardtii Truncated Hemoglobins

por Ciaccio, Chiara, Ocaña-Calahorro, Francisco, Droghetti, Enrica, Tundo, Grazia R., Sanz-Luque, Emanuel, Polticelli, Fabio, Visca, Paolo, Smulevich, Giulietta, Ascenzi, Paolo, Coletta, Massimo
Publicado 2015

Reciprocal Allosteric Modulation of Carbon Monoxide and Warfarin Binding to Ferrous Human Serum Heme-Albumin

por Bocedi, Alessio, De Sanctis, Giampiero, Ciaccio, Chiara, Tundo, Grazia R., Di Masi, Alessandra, Fanali, Gabriella, Nicoletti, Francesco P., Fasano, Mauro, Smulevich, Giulietta, Ascenzi, Paolo, Coletta, Massimo
Publicado 2013

Role of proteolytic enzymes in the COVID-19 infection and promising therapeutic approaches

por Gioia, Magda, Ciaccio, Chiara, Calligari, Paolo, De Simone, Giovanna, Sbardella, Diego, Tundo, Grazia, Fasciglione, Giovanni Francesco, Di Masi, Alessandra, Di Pierro, Donato, Bocedi, Alessio, Ascenzi, Paolo, Coletta, Massimo
Publicado 2020

Electrostatic Map Of Proteasome α-Rings Encodes The Design of Allosteric Porphyrin-Based Inhibitors Able To Affect 20S Conformation By Cooperative Binding

por Dato, Antonio Di, Cunsolo, Alessandra, Persico, Marco, Santoro, Anna Maria, D’Urso, Alessandro, Milardi, Danilo, Purrello, Roberto, Stefanelli, Manuela, Paolesse, Roberto, Tundo, Grazia R., Sbardella, Diego, Fattorusso, Caterina, Coletta, Massimo
Publicado 2017

Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells

por Benvenuto, Monica, Ciuffa, Sara, Focaccetti, Chiara, Sbardella, Diego, Fazi, Sara, Scimeca, Manuel, Tundo, Grazia Raffaella, Barillari, Giovanni, Segni, Maria, Bonanno, Elena, Manzari, Vittorio, Modesti, Andrea, Masuelli, Laura, Coletta, Massimo, Bei, Roberto
Publicado 2021

Modulation of the 20S Proteasome Activity by Porphyrin Derivatives Is Steered through Their Charge Distribution

por Persico, Marco, Santoro, Anna Maria, D’Urso, Alessandro, Milardi, Danilo, Purrello, Roberto, Cunsolo, Alessandra, Gobbo, Marina, Fattorusso, Roberto, Diana, Donatella, Stefanelli, Manuela, Tundo, Grazia R., Sbardella, Diego, Coletta, Massimo, Fattorusso, Caterina
Publicado 2022

Cationic porphyrins are tunable gatekeepers of the 20S proteasome

por Santoro, Anna M., Cunsolo, Alessandra, D'Urso, Alessandro, Sbardella, Diego, Tundo, Grazia R., Ciaccio, Chiara, Coletta, Massimiliano, Diana, Donatella, Fattorusso, Roberto, Persico, Marco, Di Dato, Antonio, Fattorusso, Caterina, Milardi, Danilo, Purrello, Roberto
Publicado 2016

Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States

por Santoro, Anna Maria, D’Urso, Alessandro, Cunsolo, Alessandra, Milardi, Danilo, Purrello, Roberto, Sbardella, Diego, Tundo, Grazia R., Diana, Donatella, Fattorusso, Roberto, Dato, Antonio Di, Paladino, Antonella, Persico, Marco, Coletta, Massimo, Fattorusso, Caterina
Publicado 2020

A novel and atypical NF-KB pro-inflammatory program regulated by a CamKII-proteasome axis is involved in the early activation of Muller glia by high glucose

por Sbardella, Diego, Tundo, Grazia Raffaella, Mecchia, Alice, Palumbo, Camilla, Atzori, Maria Grazia, Levati, Lauretta, Boccaccini, Alessandra, Caccuri, Anna Maria, Cascio, Paolo, Lacal, Pedro Miguel, Graziani, Grazia, Varano, Monica, Coletta, Massimiliano, Parravano, Mariacristina
Publicado 2022

Insulin-Degrading Enzyme Is a Non Proteasomal Target of Carfilzomib and Affects the 20S Proteasome Inhibition by the Drug

por Tundo, Grazia Raffaella, Sbardella, Diego, Oddone, Francesco, Grasso, Giuseppe, Marini, Stefano, Atzori, Maria Grazia, Santoro, Anna Maria, Milardi, Danilo, Bellia, Francesco, Macari, Gabriele, Graziani, Grazia, Polticelli, Fabio, Cascio, Paolo, Parravano, Mariacristina, Coletta, Massimo
Publicado 2022

Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

por Benvenuto, Monica, Angiolini, Valentina, Focaccetti, Chiara, Nardozi, Daniela, Palumbo, Camilla, Carrano, Raffaele, Rufini, Alessandra, Bei, Riccardo, Miele, Martino Tony, Mancini, Patrizia, Barillari, Giovanni, Cirone, Mara, Ferretti, Elisabetta, Tundo, Grazia Raffaella, Mutti, Luciano, Masuelli, Laura, Bei, Roberto
Publicado 2023

Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome

por Sbardella, Diego, Tundo, Grazia Raffaella, Campagnolo, Luisa, Valacchi, Giuseppe, Orlandi, Augusto, Curatolo, Paolo, Borsellino, Giovanna, D’Esposito, Maurizio, Ciaccio, Chiara, Cesare, Silvia Di, Pierro, Donato Di, Galasso, Cinzia, Santarone, Marta Elena, Hayek, Joussef, Coletta, Massimiliano, Marini, Stefano
Publicado 2017

Author Correction: Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome

por Sbardella, Diego, Tundo, Grazia Raffaella, Campagnolo, Luisa, Valacchi, Giuseppe, Orlandi, Augusto, Curatolo, Paolo, Borsellino, Giovanna, D’Esposito, Maurizio, Ciaccio, Chiara, Di Cesare, Silvia, Pierro, Donato Di, Galasso, Cinzia, Santarone, Marta Elena, Hayek, Joussef, Coletta, Massimiliano, Marini, Stefano
Publicado 2021