Involvement of Activation of Asparaginyl Endopeptidase in Tau Hyperphosphorylation in Repetitive Mild Traumatic Brain Injury

por Hu, Wen, Tung, Yunn Chyn, Zhang, Yanchong, Liu, Fei, Iqbal, Khalid
Publicado 2018

Tau passive immunization inhibits not only tau but also Aβ pathology

por Dai, Chun-ling, Tung, Yunn Chyn, Liu, Fei, Gong, Cheng-Xin, Iqbal, Khalid
Publicado 2017

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

por Dai, Chun-ling, Hu, Wen, Tung, Yunn Chyn, Liu, Fei, Gong, Cheng-Xin, Iqbal, Khalid
Publicado 2018

Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice

por Wei, Wei, Wang, Yifan, Liu, Yinghua, Dai, Chun-Ling, Tung, Yunn-Chyn, Liu, Fei, Iqbal, Khalid
Publicado 2020

Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction

por Wei, Wei, Liu, Yinghua, Dai, Chun-Ling, Baazaoui, Narjes, Tung, Yunn Chyn, Liu, Fei, Iqbal, Khalid
Publicado 2021

Dephosphorylation Passivates the Seeding Activity of Oligomeric Tau Derived From Alzheimer’s Brain

por Wu, Ruozhen, Li, Longfei, Shi, Ruirui, Zhou, Yan, Jin, Nana, Gu, Jianlan, Tung, Yunn Chyn, Liu, Fei, Chu, Dandan
Publicado 2021

Two simple assays for assessing the seeding activity of proteopathic tau

por Liu, Fei, Wu, Ruozhen, Jin, Nana, Chu, Dandan, Gu, Jianlan, Tung, Yunn Chyn, Hu, Zhihao, Gong, Cheng-Xin, Iqbal, Khalid
Publicado 2023

Pathological Tau From Alzheimer’s Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo

por Miao, Jin, Shi, Ruirui, Li, Longfei, Chen, Feng, Zhou, Yan, Tung, Yunn Chyn, Hu, Wen, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Publicado 2019

Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

por Jin, Nana, Gu, Jianlan, Wu, Ruozhen, Chu, Dandan, Tung, Yunn Chyn, Wegiel, Jerzy, Wisniewski, Thomas, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Publicado 2022

Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation

por Li, Longfei, Miao, Jin, Chu, Dandan, Jin, Nana, Tung, Yunn Chyn, Dai, Chun‐Ling, Hu, Wen, Gong, Cheng‐Xin, Iqbal, Khalid, Liu, Fei
Publicado 2022

Alzheimer’s disease brain contains tau fractions with differential prion-like activities

por Li, Longfei, Shi, Ruirui, Gu, Jianlan, Tung, Yunn Chyn, Zhou, Yan, Zhou, Dingwei, Wu, Ruozhen, Chu, Dandan, Jin, Nana, Deng, Kevin, Xu, Jiawei, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Publicado 2021