3D Whole-Brain Imaging Approaches to Study Brain Tumors

por Taranda, Julian, Turcan, Sevin
Publicado 2021

From Laboratory Studies to Clinical Trials: Temozolomide Use in IDH-Mutant Gliomas

por Sun, Xueyuan, Turcan, Sevin
Publicado 2021

Epigenetic Drugs and Their Immune Modulating Potential in Cancers

por Liang, Yingying, Turcan, Sevin
Publicado 2022

Epigenetic Reprogramming for Targeting IDH-Mutant Malignant Gliomas

por Park, Jong-Whi, Turcan, Şevin
Publicado 2019

Epigenetic therapy: use of agents targeting deacetylation and methylation in cancer management

por Ho, Allen S, Turcan, Sevin, Chan, Timothy A
Publicado 2013

Lack of nAChR Activity Depresses Cochlear Maturation and Up-Regulates GABA System Components: Temporal Profiling of Gene Expression in α9 Null Mice

por Turcan, Sevin, Slonim, Donna K., Vetter, Douglas E.
Publicado 2010

Changing paradigms in oncology: Toward noncytotoxic treatments for advanced gliomas

por von Knebel Doeberitz, Nikolaus, Paech, Daniel, Sturm, Dominik, Pusch, Stefan, Turcan, Sevin, Saunthararajah, Yogen
Publicado 2022

CIC reduces xCT/SLC7A11 expression and glutamate release in glioma

por Park, Jong-Whi, Kilic, Omer, Deo, Minh, Jimenez-Cowell, Kevin, Demirdizen, Engin, Kim, Hyunggee, Turcan, Şevin
Publicado 2023

Important Requirements for Desorption/Ionization Mass Spectrometric Measurements of Temozolomide-Induced 2′-Deoxyguanosine Methylations in DNA

por Fresnais, Margaux, Jung, Ina, Klein, Uli B., Miller, Aubry K., Turcan, Sevin, Haefeli, Walter E., Burhenne, Jürgen, Longuespée, Rémi
Publicado 2023

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine

por Turcan, Sevin, Fabius, Armida W. M., Borodovsky, Alexandra, Pedraza, Alicia, Brennan, Cameron, Huse, Jason, Viale, Agnes, Riggins, Gregory J., Chan, Timothy A.
Publicado 2013

Remodeling of the Methylation Landscape in Breast Cancer Metastasis

por Reyngold, Marsha, Turcan, Sevin, Giri, Dilip, Kannan, Kasthuri, Walsh, Logan A., Viale, Agnes, Drobnjak, Marija, Vahdat, Linda T., Lee, William, Chan, Timothy A.
Publicado 2014

Approaching Sites of Action of Temozolomide for Pharmacological and Clinical Studies in Glioblastoma

por Fresnais, Margaux, Turcan, Sevin, Theile, Dirk, Ungermann, Johannes, Abou Zeed, Yasmin, Lindner, Joshua Raoul, Breitkopf, Marius, Burhenne, Jürgen, Haefeli, Walter E., Longuespée, Rémi
Publicado 2021

Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas

por Wang, Yuxiang, Wild, Aaron T., Turcan, Sevin, Wu, Wei H., Sigel, Carlie, Klimstra, David S., Ma, Xiaoxiao, Gong, Yongxing, Holland, Eric C., Huse, Jason T., Chan, Timothy A.
Publicado 2020

Single-nucleus chromatin accessibility reveals intratumoral epigenetic heterogeneity in IDH1 mutant gliomas

por Al-Ali, Ruslan, Bauer, Katharina, Park, Jong-Whi, Al Abdulla, Ruba, Fermi, Valentina, von Deimling, Andreas, Herold-Mende, Christel, Mallm, Jan-Philipp, Herrmann, Carl, Wick, Wolfgang, Turcan, Şevin
Publicado 2019

5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft

por Borodovsky, Alexandra, Salmasi, Vafi, Turcan, Sevin, Fabius, Armida W. M., Baia, Gilson S., Eberhart, Charles G., Weingart, Jon D., Gallia, Gary L., Baylin, Stephen B., Chan, Timothy A., Riggins, Gregory J.
Publicado 2013

Phenotypic and molecular states of IDH1 mutation-induced CD24-positive glioma stem-like cells

por Haddock, Sara, Alban, Tyler J., Turcan, Şevin, Husic, Hana, Rosiek, Eric, Ma, Xiaoxiao, Wang, Yuxiang, Bale, Tejus, Desrichard, Alexis, Makarov, Vladimir, Monette, Sebastien, Wu, Wei, Gardner, Rui, Manova, Katia, Boire, Adrienne, Chan, Timothy A.
Publicado 2022

Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas

por Blanco-Carmona, Enrique, Narayanan, Ashwin, Hernandez, Inmaculada, Nieto, Juan C., Elosua-Bayes, Marc, Sun, Xueyuan, Schmidt, Claudia, Pamir, Necmettin, Özduman, Koray, Herold-Mende, Christel, Pagani, Francesca, Cominelli, Manuela, Taranda, Julian, Wick, Wolfgang, von Deimling, Andreas, Poliani, Pietro Luigi, Rehli, Michael, Schlesner, Matthias, Heyn, Holger, Turcan, Şevin
Publicado 2023

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

por Morris, Luc G.T., Kaufman, Andrew M., Gong, Yongxing, Ramaswami, Deepa, Walsh, Logan A., Turcan, Sevin, Eng, Stephanie, Kannan, Kasthuri, Zou, Yilong, Peng, Luke, Banuchi, Victoria E., Paty, Phillip, Zeng, Zhaoshi, Vakiani, Efsevia, Solit, David, Singh, Bhuvanesh, Ganly, Ian, Liau, Linda, Cloughesy, Timothy C., Mischel, Paul S., Mellinghoff, Ingo K., Chan, Timothy A.
Publicado 2013

IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation

por Oktay, Yavuz, Ülgen, Ege, Can, Özge, Akyerli, Cemaliye B., Yüksel, Şirin, Erdemgil, Yiğit, Durası, İ. Melis, Henegariu, Octavian Ioan, Nanni, E. Paolo, Selevsek, Nathalie, Grossmann, Jonas, Erson-Omay, E. Zeynep, Bai, Hanwen, Gupta, Manu, Lee, William, Turcan, Şevin, Özpınar, Aysel, Huse, Jason T., Sav, M. Aydın, Flanagan, Adrienne, Günel, Murat, Sezerman, O. Uğur, Yakıcıer, M. Cengiz, Pamir, M. Necmettin, Özduman, Koray
Publicado 2016

The Mutational Landscape of Adenoid Cystic Carcinoma

por Ho, Allen S., Kannan, Kasthuri, Roy, David M., Morris, Luc G.T., Ganly, Ian, Katabi, Nora, Ramaswami, Deepa, Walsh, Logan A., Eng, Stephanie, Huse, Jason T., Zhang, Jianan, Dolgalev, Igor, Huberman, Kety, Heguy, Adriana, Viale, Agnes, Drobnjak, Marija, Leversha, Margaret A., Rice, Christine E., Singh, Bhuvanesh, Iyer, N. Gopalakrishna, Leemans, C. Rene, Bloemena, Elisabeth, Ferris, Robert L., Seethala, Raja R., Gross, Benjamin E., Liang, Yupu, Sinha, Rileen, Peng, Luke, Raphael, Benjamin J., Turcan, Sevin, Gong, Yongxing, Schultz, Nikolaus, Kim, Seungwon, Chiosea, Simion, Shah, Jatin P., Sander, Chris, Lee, William, Chan, Timothy A.
Publicado 2013