Advances in Gene Delivery Methods to Label and Modulate Activity of Upper Motor Neurons: Implications for Amyotrophic Lateral Sclerosis

por Haidar, Mouna, Viden, Aida, Turner, Bradley J.
Publicado 2021

Metabolic Dysfunction in Motor Neuron Disease: Shedding Light through the Lens of Autophagy

por De Silva, Subhavi, Turner, Bradley J., Perera, Nirma D.
Publicado 2022

Could an Impairment in Local Translation of mRNAs in Glia be Contributing to Pathogenesis in ALS?

por Barton, Samantha K., Gregory, Jenna M., Chandran, Siddharthan, Turner, Bradley J.
Publicado 2019

Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation

por Dastpeyman, Mohadeseh, Karas, John A., Amin, Azin, Turner, Bradley J., Shabanpoor, Fazel
Publicado 2021

Application of Urine-Derived Stem Cells to Cellular Modeling in Neuromuscular and Neurodegenerative Diseases

por Sato, Mitsuto, Takizawa, Hotake, Nakamura, Akinori, Turner, Bradley J., Shabanpoor, Fazel, Aoki, Yoshitsugu
Publicado 2019

Amyotrophic Lateral Sclerosis and Autophagy: Dysfunction and Therapeutic Targeting

por Amin, Azin, Perera, Nirma D., Beart, Philip M., Turner, Bradley J., Shabanpoor, Fazel
Publicado 2020

TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy

por Turner, Bradley J, Bäumer, Dirk, Parkinson, Nicholas J, Scaber, Jakub, Ansorge, Olaf, Talbot, Kevin
Publicado 2008

Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models

por Perera, Nirma D., Sheean, Rebecca K., Scott, John W., Kemp, Bruce E., Horne, Malcolm K., Turner, Bradley J.
Publicado 2014

Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice

por Sheean, Rebecca K, Weston, Richard H, Perera, Nirma D, D’Amico, Angela, Nutt, Stephen L, Turner, Bradley J
Publicado 2015

Dissociation of disease onset, progression and sex differences from androgen receptor levels in a mouse model of amyotrophic lateral sclerosis

por Tomas, Doris, McLeod, Victoria M., Chiam, Mathew D. F., Wanniarachchillage, Nayomi, Boon, Wah C., Turner, Bradley J.
Publicado 2021

Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice

por Turner, Bradley J., Alfazema, Neza, Sheean, Rebecca K., Sleigh, James N., Davies, Kay E., Horne, Malcolm K., Talbot, Kevin
Publicado 2014

Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1(G93A) Mice Reveals Widespread Loss of Androgen Receptor Occurring Early in Spinal Motor Neurons

por McLeod, Victoria M., Chiam, Mathew D. F., Perera, Nirma D., Lau, Chew L., Boon, Wah Chin, Turner, Bradley J.
Publicado 2022

α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of...

por Zanganeh, Pardis F., Barton, Samantha K., Lim, Katherine, Qian, Elizabeth L., Crombie, Duncan E., Bye, Christopher R., Turner, Bradley J.
Publicado 2022

Altered Blood–Brain Barrier Dynamics in the C9orf72 Hexanucleotide Repeat Expansion Mouse Model of Amyotrophic Lateral Sclerosis

por Pan, Yijun, Kagawa, Yoshiteru, Sun, Jiaqi, Turner, Bradley J., Huang, Cheng, Shah, Anup D., Schittenhelm, Ralf B., Nicolazzo, Joseph A.
Publicado 2022

Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression

por Perera, Nirma D., Sheean, Rebecca K., Lau, Chew L., Shin, Yea Seul, Beart, Philip M., Horne, Malcolm K., Turner, Bradley J.
Publicado 2017

Emerging therapies and challenges in spinal muscular atrophy

por Farrar, Michelle A., Park, Susanna B., Vucic, Steve, Carey, Kate A., Turner, Bradley J., Gillingwater, Thomas H., Swoboda, Kathryn J., Kiernan, Matthew C.
Publicado 2017

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

por Lee, John D, Kamaruzaman, Nur A, Fung, Jenny NT, Taylor, Stephen M, Turner, Bradley J, Atkin, Julie D, Woodruff, Trent M, Noakes, Peter G
Publicado 2013

Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis

por Sadler, Gemma L., Lewis, Katherine N., Narayana, Vinod K., De Souza, David P., Mason, Joel, McLean, Catriona, Gonsalvez, David G., Turner, Bradley J., Barton, Samantha K.
Publicado 2022

ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation

por Walker, Adam K., Soo, Kai Y., Sundaramoorthy, Vinod, Parakh, Sonam, Ma, Yi, Farg, Manal A., Wallace, Robyn H., Crouch, Peter J., Turner, Bradley J., Horne, Malcolm K., Atkin, Julie D.
Publicado 2013

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

por Winbanks, Catherine E., Chen, Justin L., Qian, Hongwei, Liu, Yingying, Bernardo, Bianca C., Beyer, Claudia, Watt, Kevin I., Thomson, Rachel E., Connor, Timothy, Turner, Bradley J., McMullen, Julie R., Larsson, Lars, McGee, Sean L., Harrison, Craig A., Gregorevic, Paul
Publicado 2013