Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer

por Jain, Vikram K, Turner, Nicholas C
Publicado 2012

Platinum chemotherapy for BRCA1-related breast cancer: do we need more evidence?

por Turner, Nicholas C, Tutt, Andrew NJ
Publicado 2012

Determination of HER2 Amplification Status on Tumour DNA by Digital PCR

por Garcia-Murillas, Isaac, Lambros, Maryou, Turner, Nicholas C.
Publicado 2013

An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer

por Garcia-Murillas, Isaac, Sharpe, Rachel, Pearson, Alex, Campbell, James, Natrajan, Rachael, Ashworth, Alan, Turner, Nicholas C
Publicado 2013

Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition

por López-Knowles, Elena, Segal, Corrinne V, Gao, Qiong, Garcia-Murillas, Isaac, Turner, Nicholas C, Smith, Ian, Martin, Lesley-Ann, Dowsett, Mitch
Publicado 2014

Operational complexity versus design efficiency: challenges of implementing a phase IIa multiple parallel cohort targeted treatment platform trial in advanced breast cancer

por Snowdon, Claire, Kernaghan, Sarah, Moretti, Laura, Turner, Nicholas C., Ring, Alistair, Wilkinson, Katie, Martin, Sue, Foster, Stephanie, Kilburn, Lucy S., Bliss, Judith M.
Publicado 2022

FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis

por Elbauomy Elsheikh, Somaia, Green, Andrew R, Lambros, Maryou BK, Turner, Nicholas C, Grainge, Matthew J, Powe, Des, Ellis, Ian O, Reis-Filho, Jorge S
Publicado 2007

PIK3CA mutation enrichment and quantitation from blood and tissue

por Keraite, Ieva, Alvarez-Garcia, Virginia, Garcia-Murillas, Isaac, Beaney, Matthew, Turner, Nicholas C., Bartos, Clare, Oikonomidou, Olga, Kersaudy-Kerhoas, Maïwenn, Leslie, Nicholas R.
Publicado 2020

Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype

por Fitzpatrick, Amanda, Iravani, Marjan, Mills, Adam, Vicente, David, Alaguthurai, Thanussuyah, Roxanis, Ioannis, Turner, Nicholas C., Haider, Syed, Tutt, Andrew N. J., Isacke, Clare M.
Publicado 2023

Next Generation Sequencing Assay for Detection of Circulating HPV DNA (cHPV-DNA) in Patients Undergoing Radical (Chemo)Radiotherapy in Anal Squamous Cell Carcinoma (ASCC)

por Lee, Jen Y., Cutts, Rosalind J., White, Ingrid, Augustin, Yolanda, Garcia-Murillas, Isaac, Fenwick, Kerry, Matthews, Nik, Turner, Nicholas C., Harrington, Kevin, Gilbert, Duncan C., Bhide, Shreerang
Publicado 2020

Circulating Tumor DNA Markers for Early Progression on Fulvestrant With or Without Palbociclib in ER+ Advanced Breast Cancer

por O’Leary, Ben, Cutts, Rosalind J, Huang, Xin, Hrebien, Sarah, Liu, Yuan, André, Fabrice, Loibl, Sibylle, Loi, Sherene, Garcia-Murillas, Isaac, Cristofanilli, Massimo, Bartlett, Cynthia Huang, Turner, Nicholas C
Publicado 2020

Prognostic Factors for Overall Survival in Patients with Hormone Receptor‐Positive Advanced Breast Cancer: Analyses From PALOMA‐3

por Rugo, Hope S., Cristofanilli, Massimo, Loibl, Sybille, Harbeck, Nadia, DeMichele, Angela, Iwata, Hiroji, Park, Yoon Hee, Brufsky, Adam, Theall, Kathy Puyana, Huang, Xin, McRoy, Lynn, Bananis, Eustratios, Turner, Nicholas C.
Publicado 2021

Neratinib in advanced HER2-positive breast cancer: experience from the royal Marsden hospital

por Cunningham, Niamh, Shepherd, Scott, Mohammed, Kabir, Lee, Karla A., Allen, Mark, Johnston, Stephen, Kipps, Emma, McGrath, Sophie, Noble, Jillian, Parton, Marina, Ring, Alistair, Turner, Nicholas C., Okines, Alicia F. C.
Publicado 2022

Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets

por Iorns, Elizabeth, Lord, Christopher J., Grigoriadis, Anita, McDonald, Sarah, Fenwick, Kerry, MacKay, Alan, Mein, Charles A., Natrajan, Rachael, Savage, Kay, Tamber, Narinder, Reis-Filho, Jorge S., Turner, Nicholas C., Ashworth, Alan
Publicado 2009

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

por Litchfield, Kevin, Summersgill, Brenda, Yost, Shawn, Sultana, Razvan, Labreche, Karim, Dudakia, Darshna, Renwick, Anthony, Seal, Sheila, Al-Saadi, Reem, Broderick, Peter, Turner, Nicholas C., Houlston, Richard S., Huddart, Robert, Shipley, Janet, Turnbull, Clare
Publicado 2015

Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach

por Pender, Alexandra, Garcia-Murillas, Isaac, Rana, Sareena, Cutts, Rosalind J., Kelly, Gavin, Fenwick, Kerry, Kozarewa, Iwanka, Gonzalez de Castro, David, Bhosle, Jaishree, O’Brien, Mary, Turner, Nicholas C., Popat, Sanjay, Downward, Julian
Publicado 2015

Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer

por O’Leary, Ben, Hrebien, Sarah, Morden, James P., Beaney, Matthew, Fribbens, Charlotte, Huang, Xin, Liu, Yuan, Bartlett, Cynthia Huang, Koehler, Maria, Cristofanilli, Massimo, Garcia-Murillas, Isaac, Bliss, Judith M., Turner, Nicholas C.
Publicado 2018

Long-term Pooled Safety Analysis of Palbociclib in Combination With Endocrine Therapy for HR+/HER2- Advanced Breast Cancer

por Diéras, Véronique, Rugo, Hope S, Schnell, Patrick, Gelmon, Karen, Cristofanilli, Massimo, Loi, Sherene, Colleoni, Marco, Lu, Dongrui R, Mori, Ave, Gauthier, Eric, Huang Bartlett, Cynthia, Slamon, Dennis J, Turner, Nicholas C, Finn, Richard S
Publicado 2018

Long‐Term Pooled Safety Analysis of Palbociclib in Combination with Endocrine Therapy for Hormone Receptor‐Positive/Human Epidermal Growth Factor Receptor 2‐Negative Advanced Breas...

por Finn, Richard S., Rugo, Hope S., Gelmon, Karen A., Cristofanilli, Massimo, Colleoni, Marco, Loi, Sherene, Schnell, Patrick, Lu, Dongrui R., Theall, Kathy Puyana, Mori, Ave, Gauthier, Eric, Bananis, Eustratios, Turner, Nicholas C., Diéras, Véronique
Publicado 2021

Treatment effect of palbociclib plus endocrine therapy by prognostic and intrinsic subtype and biomarker analysis in patients with bone-only disease: a joint analysis of PALOMA-2 a...

por Finn, Richard S., Cristofanilli, Massimo, Ettl, Johannes, Gelmon, Karen A., Colleoni, Marco, Giorgetti, Carla, Gauthier, Eric, Liu, Yuan, Lu, Dongrui R., Zhang, Zhe, Bartlett, Cynthia Huang, Slamon, Dennis J., Turner, Nicholas C., Rugo, Hope S.
Publicado 2020