The brain‐penetrant ATM inhibitor, AZD1390, promotes axon regeneration and functional recovery in preclinical models of spinal cord injury

por Ahmed, Zubair, Tuxworth, Richard I.
Publicado 2022

Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β

por Povellato, Giulia, Tuxworth, Richard I., Hanger, Diane P., Tear, Guy
Publicado 2013

Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways

por Tuxworth, Richard I., Vivancos, Valérie, O'Hare, Megan B., Tear, Guy
Publicado 2009

The Batten disease gene CLN3 is required for the response to oxidative stress

por Tuxworth, Richard I., Chen, Haiyang, Vivancos, Valerie, Carvajal, Nancy, Huang, Xun, Tear, Guy
Publicado 2011

in vivo localization of the neuronal ceroid lipofuscinosis proteins, CLN3 and CLN7, at endogenous expression levels

por Mohammed, Alamin, O'Hare, Megan B., Warley, Alice, Tear, Guy, Tuxworth, Richard I.
Publicado 2017

Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury

por Taylor, Matthew J., Thompson, Adam M., Alhajlah, Sharif, Tuxworth, Richard I., Ahmed, Zubair
Publicado 2022

Dictyostelium RasG Is Required for Normal Motility and Cytokinesis, But Not Growth

por Tuxworth, Richard I., Cheetham, Janet L., Machesky, Laura M., Spiegelmann, George B., Weeks, Gerald, Insall, Robert H.
Publicado 1997

Dysregulation of autophagy as a common mechanism in lysosomal storage diseases

por Seranova, Elena, Connolly, Kyle J., Zatyka, Malgorzata, Rosenstock, Tatiana R., Barrett, Timothy, Tuxworth, Richard I., Sarkar, Sovan
Publicado 2017

The neuronal ceroid lipofuscinosis protein Cln7 functions in the postsynaptic cell to regulate synapse development

por Connolly, Kyle J., O’Hare, Megan B., Mohammed, Alamin, Aitchison, Katelyn M., Anthoney, Niki C., Taylor, Matthew J., Stewart, Bryan A., Tuxworth, Richard I., Tear, Guy
Publicado 2019

Attenuating the DNA damage response to double-strand breaks restores function in models of CNS neurodegeneration

por Tuxworth, Richard I, Taylor, Matthew J, Martin Anduaga, Ane, Hussien-Ali, Alaa, Chatzimatthaiou, Sotiroula, Longland, Joanne, Thompson, Adam M, Almutiri, Sharif, Alifragis, Pavlos, Kyriacou, Charalambos P, Kysela, Boris, Ahmed, Zubair
Publicado 2019