Modulation of the Unfolded Protein Response During Hepatocyte and Cardiomyocyte Apoptosis In Trauma/Hemorrhagic Shock

por Thacker, Stephen A., Robinson, Prema, Abel, Adam, Tweardy, David J.
Publicado 2013

Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment

por Kasembeli, Moses M., Bharadwaj, Uddalak, Robinson, Prema, Tweardy, David J.
Publicado 2018

Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

por Bharadwaj, Uddalak, Kasembeli, Moses M., Robinson, Prema, Tweardy, David J.
Publicado 2020

Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis

por Garza, Armandina, Tweardy, David J., Weinstock, Joel, Viswanathan, Balaji, Robinson, Prema
Publicado 2010

Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis

por Roh, Soung-Hun, Kasembeli, Moses, Bakthavatsalam, Deenadayalan, Chiu, Wah, Tweardy, David J.
Publicado 2015

Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation

por Xu, Xuejun, Kasembeli, Moses M., Jiang, Xueqing, Tweardy, Benjamin J., Tweardy, David J.
Publicado 2009

Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance

por Robinson, Prema, Kasembeli, Moses, Bharadwaj, Uddalak, Engineer, Nikita, Eckols, Kris T., Tweardy, David J.
Publicado 2016

Aberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers

por Kasembeli, Moses M., Kaparos, Efiyenia, Bharadwaj, Uddalak, Allaw, Ahmad, Khouri, Alain, Acot, Bianca, Tweardy, David J.
Publicado 2023

Genetic and Small-Molecule Modulation of Stat3 in a Mouse Model of Crohn’s Disease

por Robinson, Prema, Magness, Emily, Montoya, Kelsey, Engineer, Nikita, Eckols, Thomas K., Rodriguez, Emma, Tweardy, David J.
Publicado 2022

Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin

por Kasembeli, Moses, Lau, Wilson Chun Yu, Roh, Soung-Hun, Eckols, T. Kris, Frydman, Judith, Chiu, Wah, Tweardy, David J.
Publicado 2014

IL-6-Mediated Activation of Stat3α Prevents Trauma/Hemorrhagic Shock-Induced Liver Inflammation

por Moran, Ana, Thacker, Stephen A., Arikan, Ayse Akcan, Mastrangelo, Mary-Ann A., Wu, Yong, Yu, Bi, Tweardy, David J.
Publicado 2011

Substance P Causes Seizures in Neurocysticercosis

por Robinson, Prema, Garza, Armandina, Weinstock, Joel, Serpa, Jose A., Goodman, Jerry Clay, Eckols, Kristian T., Firozgary, Bahrom, Tweardy, David J.
Publicado 2012

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer

por Bharadwaj, Uddalak, Kasembeli, Moses M., Eckols, T. Kris, Kolosov, Mikhail, Lang, Paul, Christensen, Kurt, Edwards, Dean P., Tweardy, David J.
Publicado 2014

Prevention of Hypovolemic Circulatory Collapse by IL-6 Activated Stat3

por Alten, Jeffrey A., Moran, Ana, Tsimelzon, Anna I., Mastrangelo, Mary-Ann A., Hilsenbeck, Susan G., Poli, Valeria, Tweardy, David J.
Publicado 2008

Correction: Prevention of Hypovolemic Circulatory Collapse by IL-6 Activated Stat3

por Alten, Jeffrey A., Moran, Ana, Tsimelzon, Anna I., Mastrangelo, Mary-Ann A., Hilsenbeck, Susan G., Poli, Valeria, Tweardy, David J.
Publicado 2008

Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy

por Hoffman, Kristyn A., Villar, Maria Jose, Poveda, Cristina, Bottazzi, Maria Elena, Hotez, Peter J., Tweardy, David J., Jones, Kathryn M.
Publicado 2021

TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain

por Kasembeli, Moses M., Singhmar, Pooja, Ma, Jiacheng, Edralin, Jules, Tang, Yongfu, Adams, Clydell, Heijnen, Cobi J., Kavelaars, Annemieke, Tweardy, David J.
Publicado 2021

Spatial molecular and cellular determinants of STAT3 activation in liver fibrosis progression in non-alcoholic fatty liver disease

por Jiao, Jingjing, Sanchez, Jessica I., Saldarriaga, Omar A., Solis, Luisa M., Tweardy, David J., Maru, Dipen M., Stevenson, Heather L., Beretta, Laura
Publicado 2022

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

por Bharadwaj, Uddalak, Eckols, T. Kris, Xu, Xuejun, Kasembeli, Moses M., Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y., Tweardy, David J.
Publicado 2016

Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

por Bharadwaj, Uddalak, Eckols, T. Kris, Xu, Xuejun, Kasembeli, Moses M., Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y., Tweardy, David J.
Publicado 2019