The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly

por Dowd, Kelley J., Tweten, Rodney K.
Publicado 2012

Correction: The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly

por Dowd, Kelley J., Tweten, Rodney K.
Publicado 2012

Disulfide-Bond Scanning Reveals Assembly State and β-Strand Tilt Angle of PFO β-Barrel

por Sato, Takehiro K., Tweten, Rodney K., Johnson, Arthur E.
Publicado 2013

Mouse, but Not Human, ApoB-100 Lipoprotein Cholesterol Is a Potent Innate Inhibitor of Streptococcus pneumoniae Pneumolysin

por Wade, Kristin R., Hotze, Eileen M., Briles, David E., Tweten, Rodney K.
Publicado 2014

An Intermolecular π-Stacking Interaction Drives Conformational Changes Necessary to β-Barrel Formation in a Pore-Forming Toxin

por Burns, Joshua R., Morton, Craig J., Parker, Michael W., Tweten, Rodney K.
Publicado 2019

The Pore-Forming Toxin Listeriolysin O Mediates a Novel Entry Pathway of L. monocytogenes into Human Hepatocytes

por Vadia, Stephen, Arnett, Eusondia, Haghighat, Anne-Cécile, Wilson-Kubalek, Elisabeth M., Tweten, Rodney K., Seveau, Stephanie
Publicado 2011

The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent

por Harvey, Richard M., Hughes, Catherine E., Paton, Adrienne W., Trappetti, Claudia, Tweten, Rodney K., Paton, James C.
Publicado 2014

Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid

por Thanawastien, Ann, Joyce, Kelsey E., Cartee, Robert T., Haines, Laurel A., Pelton, Stephen I., Tweten, Rodney K., Killeen, Kevin P.
Publicado 2020

Immunotherapy targeting the Streptococcus pyogenes M protein or streptolysin O to treat or prevent influenza A superinfection

por Herrera, Andrea L., Van Hove, Christopher, Hanson, Mary, Dale, James B., Tweten, Rodney K., Huber, Victor C., Diel, Diego, Chaussee, Michael S.
Publicado 2020

A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins

por Evans, Jordan C., Johnstone, Bronte A., Lawrence, Sara L., Morton, Craig J., Christie, Michelle P., Parker, Michael W., Tweten, Rodney K.
Publicado 2020

Perfringolysin O: The Underrated Clostridium perfringens Toxin?

por Verherstraeten, Stefanie, Goossens, Evy, Valgaeren, Bonnie, Pardon, Bart, Timbermont, Leen, Haesebrouck, Freddy, Ducatelle, Richard, Deprez, Piet, Wade, Kristin R., Tweten, Rodney, Van Immerseel, Filip
Publicado 2015

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

por Lawrence, Sara L., Feil, Susanne C., Holien, Jessica K., Kuiper, Michael J., Doughty, Larissa, Dolezal, Olan, Mulhern, Terrence D., Tweten, Rodney K., Parker, Michael W.
Publicado 2012

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

por Lawrence, Sara L., Feil, Susanne C., Morton, Craig J., Farrand, Allison J., Mulhern, Terrence D., Gorman, Michael A., Wade, Kristin R., Tweten, Rodney K., Parker, Michael W.
Publicado 2015

A proteolytically activated antimicrobial toxin encoded on a mobile plasmid of Bacteroidales induces a protective response

por Evans, Jordan C., McEneany, Valentina Laclare, Coyne, Michael J., Caldwell, Elizabeth P., Sheahan, Madeline L., Von, Salena S., Coyne, Emily M., Tweten, Rodney K., Comstock, Laurie E.
Publicado 2022

The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin

por Wade, Kristin R., Lawrence, Sara L., Farrand, Allison J., Hotze, Eileen M., Kuiper, Michael J., Gorman, Michael A., Christie, Michelle P., Panjikar, Santosh, Morton, Craig J., Parker, Michael W., Tweten, Rodney K.
Publicado 2019

Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin

por Lukoyanova, Natalya, Kondos, Stephanie C., Farabella, Irene, Law, Ruby H. P., Reboul, Cyril F., Caradoc-Davies, Tom T., Spicer, Bradley A., Kleifeld, Oded, Traore, Daouda A. K., Ekkel, Susan M., Voskoboinik, Ilia, Trapani, Joseph A., Hatfaludi, Tamas, Oliver, Katherine, Hotze, Eileen M., Tweten, Rodney K., Whisstock, James C., Topf, Maya, Saibil, Helen R., Dunstone, Michelle A.
Publicado 2015