BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival

por Jacque, Emilie, Schweighoffer, Edina, Tybulewicz, Victor L.J., Ley, Steven C.
Publicado 2015

TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK

por Schweighoffer, Edina, Nys, Josquin, Vanes, Lesley, Smithers, Nicholas, Tybulewicz, Victor L.J.
Publicado 2017

Down syndrome—recent progress and future prospects

por Wiseman, Frances K., Alford, Kate A., Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.
Publicado 2009

Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21

por Ruparelia, Aarti, Wiseman, Frances, Sheppard, Olivia, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.
Publicado 2010

Generation of a panel of antibodies against proteins encoded on human chromosome 21

por Wiseman, Frances K, Sheppard, Olivia, Linehan, Jacqueline M, Brandner, Sebastian, Tybulewicz, Victor LJ, Fisher, Elizabeth MC
Publicado 2010

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

por Schweighoffer, Edina, Vanes, Lesley, Nys, Josquin, Cantrell, Doreen, McCleary, Scott, Smithers, Nicholas, Tybulewicz, Victor L.J.
Publicado 2013

Vav1 Transduces T Cell Receptor Signals to the Activation of Phospholipase C-γ1 via Phosphoinositide 3-Kinase-dependent and -independent Pathways

por Reynolds, Lucinda F., Smyth, Lesley A., Norton, Trisha, Freshney, Norman, Downward, Julian, Kioussis, Dimitris, Tybulewicz, Victor L.J.
Publicado 2002

In vivo and ex vivo analyses of amyloid toxicity in the Tc1 mouse model of Down syndrome

por Naert, Gaëlle, Ferré, Valentine, Keller, Emeline, Slender, Amy, Gibbins, Dorota, Fisher, Elizabeth MC, Tybulewicz, Victor LJ, Maurice, Tangui
Publicado 2017

The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome

por Duchon, Arnaud, Pothion, Stéphanie, Brault, Véronique, Sharp, Andrew J., Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Herault, Yann
Publicado 2011

Syk Tyrosine Kinase Is Required for the Positive Selection of Immature B Cells into the Recirculating B Cell Pool

por Turner, Martin, Gulbranson-Judge, Adam, Quinn, Marian E., Walters, Alice E., MacLennan, Ian C.M., Tybulewicz, Victor L.J.
Publicado 1997

Vav1 GEF activity is required for T cell mediated allograft rejection

por Haubert, Dirk, Li, Jianping, Saveliev, Alexander, Calzascia, Thomas, Sutter, Esther, Metzler, Barbara, Kaiser, Daniel, Tybulewicz, Victor L.J., Weckbecker, Gisbert
Publicado 2012

Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory

por Hall, Jessica H., Wiseman, Frances K., Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Harwood, John L., Good, Mark A.
Publicado 2016

Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival

por Müller-Winkler, Jennifer, Mitter, Richard, Rappe, Julie C.F., Vanes, Lesley, Schweighoffer, Edina, Mohammadi, Hamid, Wack, Andreas, Tybulewicz, Victor L.J.
Publicado 2020

Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome

por Galante, Micaela, Jani, Harsha, Vanes, Lesley, Daniel, Hervé, Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Bliss, Timothy V.P., Morice, Elise
Publicado 2009

A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival

por Henderson, Robert B., Grys, Katarzyna, Vehlow, Anne, de Bettignies, Carine, Zachacz, Agnieszka, Henley, Tom, Turner, Martin, Batista, Facundo, Tybulewicz, Victor L.J.
Publicado 2010

Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain

por Ahmed, Md. Mahiuddin, Dhanasekaran, A. Ranjitha, Tong, Suhong, Wiseman, Frances K., Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Gardiner, Katheleen J.
Publicado 2013

IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen

por Jacque, Emilie, Schweighoffer, Edina, Visekruna, Alexander, Papoutsopoulou, Stamatia, Janzen, Julia, Zillwood, Rachel, Tarlinton, David M., Tybulewicz, Victor L.J., Ley, Steven C.
Publicado 2014

Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel

por Lana-Elola, Eva, Watson-Scales, Sheona, Slender, Amy, Gibbins, Dorota, Martineau, Alexandrine, Douglas, Charlotte, Mohun, Timothy, Fisher, Elizabeth MC, Tybulewicz, Victor LJ
Publicado 2016

Correction: Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel

por Lana-Elola, Eva, Watson-Scales, Sheona, Slender, Amy, Gibbins, Dorota, Martineau, Alexandrine, Douglas, Charlotte, Mohun, Timothy, Fisher, Elizabeth MC, Tybulewicz, Victor LJ
Publicado 2020

Critical role of WNK1 in MYC-dependent early mouse thymocyte development

por Köchl, Robert, Vanes, Lesley, Llorian Sopena, Miriam, Chakravarty, Probir, Hartweger, Harald, Fountain, Kathryn, White, Andrea, Cowan, Jennifer, Anderson, Graham, Tybulewicz, Victor LJ
Publicado 2020