A four-compartment PBPK heart model accounting for cardiac metabolism - model development and application

por Tylutki, Zofia, Polak, Sebastian
Publicado 2017

Top-down, Bottom-up and Middle-out Strategies for Drug Cardiac Safety Assessment via Modeling and Simulations

por Tylutki, Zofia, Polak, Sebastian, Wiśniowska, Barbara
Publicado 2016

Humans Vary, So Cardiac Models Should Account for That Too!

por Wiśniowska, Barbara, Tylutki, Zofia, Polak, Sebastian
Publicado 2017

Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics...

por Tylutki, Zofia, Mendyk, Aleksander, Polak, Sebastian
Publicado 2018

Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trials

por Wiśniowska, Barbara, Tylutki, Zofia, Wyszogrodzka, Gabriela, Polak, Sebastian
Publicado 2016

Model of the Distribution of Diastolic Left Ventricular Posterior Wall Thickness in Healthy Adults and Its Impact on the Behavior of a String of Virtual Cardiomyocytes

por Fijorek, Kamil, Tanner, Felix C., Stähli, Barbara E., Gielerak, Grzegorz, Krzesinski, Pawel, Uzieblo-Zyczkowska, Beata, Smurzynski, Pawel, Stanczyk, Adam, Stolarz-Skrzypek, Katarzyna, Kawecka-Jaszcz, Kalina, Jastrzebski, Marek, Podolec, Mateusz, Kopec, Grzegorz, Stanula, Barbara, Kocowska, Maryla, Tylutki, Zofia, Polak, Sebastian
Publicado 2014