Fractional Proliferation: A method to deconvolve cell population dynamics from single-cell data

por Tyson, Darren R., Garbett, Shawn P., Frick, Peter L., Quaranta, Vito
Publicado 2012

Purinergic calcium signaling drives drug tolerance through ERK reactivation in BRAF-mutant melanoma

por Stauffer, Philip E., Brinkley, Jordon, Jacobson, David, Quaranta, Vito, Tyson, Darren R.
Publicado 2023

A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase

por Jones, Zack W., Leander, Rachel, Quaranta, Vito, Harris, Leonard A., Tyson, Darren R.
Publicado 2018

Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines

por Wandishin, Clayton M., Robbins, Charles John, Tyson, Darren R., Harris, Leonard A., Quaranta, Vito
Publicado 2022

Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity

por Groves, Sarah M., Panchy, Nicholas, Tyson, Darren R., Harris, Leonard A., Quaranta, Vito, Hong, Tian
Publicado 2023

Thunor: visualization and analysis of high-throughput dose–response datasets

por Lubbock, Alexander L R, Harris, Leonard A, Quaranta, Vito, Tyson, Darren R, Lopez, Carlos F
Publicado 2021

An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability

por Hayford, Corey E., Tyson, Darren R., Robbins, C. Jack, Frick, Peter L., Quaranta, Vito, Harris, Leonard A.
Publicado 2021

Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma

por Bergdorf, Kensey, Bauer, Joshua A., Westover, David, Phifer, Courtney, Murphy, Barbara, Tyson, Darren R., Lee, Ethan, Weiss, Vivian L.
Publicado 2022

A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer

por McKenna, Matthew T., Weis, Jared A., Barnes, Stephanie L., Tyson, Darren R., Miga, Michael I., Quaranta, Vito, Yankeelov, Thomas E.
Publicado 2017

Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers

por Wooten, David J., Groves, Sarah M., Tyson, Darren R., Liu, Qi, Lim, Jing S., Albert, Réka, Lopez, Carlos F., Sage, Julien, Quaranta, Vito
Publicado 2019

An unbiased metric of antiproliferative drug effect in vitro

por Harris, Leonard A., Frick, Peter L., Garbett, Shawn P., Hardeman, Keisha N., Paudel, B. Bishal, Lopez, Carlos F., Quaranta, Vito, Tyson, Darren R.
Publicado 2016

Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition

por Hardeman, Keisha N., Peng, Chengwei, Paudel, Bishal B., Meyer, Christian T., Luong, Thong, Tyson, Darren R., Young, Jamey D., Quaranta, Vito, Fessel, Joshua P.
Publicado 2017

Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model

por Tsunoda, Toshiyuki, Ota, Takeharu, Fujimoto, Takahiro, Doi, Keiko, Tanaka, Yoko, Yoshida, Yasuhiro, Ogawa, Masahiro, Matsuzaki, Hiroshi, Hamabashiri, Masato, Tyson, Darren R, Kuroki, Masahide, Miyamoto, Shingo, Shirasawa, Senji
Publicado 2012

ACDC: Automated Cell Detection and Counting for Time-Lapse Fluorescence Microscopy

por Rundo, Leonardo, Tangherloni, Andrea, Tyson, Darren R., Betta, Riccardo, Militello, Carmelo, Spolaor, Simone, Nobile, Marco S., Besozzi, Daniela, Lubbock, Alexander L. R., Quaranta, Vito, Mauri, Giancarlo, Lopez, Carlos F., Cazzaniga, Paolo
Publicado 2020

Addressing persistent challenges in digital image analysis of cancerous tissues

por Prabhakaran, Sandhya, Yapp, Clarence, Baker, Gregory J., Beyer, Johanna, Chang, Young Hwan, Creason, Allison L., Krueger, Robert, Muhlich, Jeremy, Patterson, Nathan Heath, Sidak, Kevin, Sudar, Damir, Taylor, Adam J., Ternes, Luke, Troidl, Jakob, Xie, Yubin, Sokolov, Artem, Tyson, Darren R.
Publicado 2023