Thalamocortical neurons display suppressed burst-firing due to an enhanced I(h) current in a genetic model of absence epilepsy

por Cain, Stuart M., Tyson, John R., Jones, Karen L., Snutch, Terrance P.
Publicado 2014

MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome

por Tyson, John R., O'Neil, Nigel J., Jain, Miten, Olsen, Hugh E., Hieter, Philip, Snutch, Terrance P.
Publicado 2018

Peripheral nerve injury increases contribution of L-type calcium channels to synaptic transmission in spinal lamina II: Role of α2δ–1 subunits

por Alles, Sascha RA, Garcia, Esperanza, Balasubramanyan, Sridhar, Jones, Karen, Tyson, John R, Joy, Twinkle, Snutch, Terrance P, Smith, Peter A
Publicado 2018

Assessing Multiplex Tiling PCR Sequencing Approaches for Detecting Genomic Variants of SARS-CoV-2 in Municipal Wastewater

por Lin, Xuan, Glier, Melissa, Kuchinski, Kevin, Ross-Van Mierlo, Tenysha, McVea, David, Tyson, John R., Prystajecky, Natalie, Ziels, Ryan M.
Publicado 2021

Spike Mutation Profiles Associated With SARS-CoV-2 Breakthrough Infections in Delta Emerging and Predominant Time Periods in British Columbia, Canada

por Fibke, Chad D., Joffres, Yayuk, Tyson, John R., Colijn, Caroline, Janjua, Naveed Z., Fjell, Chris, Prystajecky, Natalie, Jassem, Agatha, Sbihi, Hind
Publicado 2022

Mutations in emerging variant of concern lineages disrupt genomic sequencing of SARS-CoV-2 clinical specimens

por Kuchinski, Kevin S., Nguyen, Jason, Lee, Tracy D., Hickman, Rebecca, Jassem, Agatha N., Hoang, Linda M.N., Prystajecky, Natalie A., Tyson, John R.
Publicado 2022

Heantos-4, a natural plant extract used in the treatment of drug addiction, modulates T-type calcium channels and thalamocortical burst-firing

por Cain, Stuart M., Ahn, Soyon, Garcia, Esperanza, Zhang, Yiming, Waheed, Zeina, Tyson, John R., Yang, Yi, Van Sung, Tran, Phillips, Anthony G., Snutch, Terrance P.
Publicado 2016

A framework for real-time monitoring, analysis and adaptive sampling of viral amplicon nanopore sequencing

por Munro, Rory, Holmes, Nadine, Moore, Christopher, Carlile, Matthew, Payne, Alexander, Tyson, John R., Williams, Thomas, Alder, Christopher, Snell, Luke B., Nebbia, Gaia, Santos, Roberto, Loose, Matt
Publicado 2023

Emergence of SARS-CoV-2 Delta Variant and Effect of Nonpharmaceutical Interventions, British Columbia, Canada

por Chan, Y.L. Elaine, Irvine, Michael A., Prystajecky, Natalie, Sbihi, Hind, Taylor, Marsha, Joffres, Yayuk, Schertzer, Andrea, Rose, Caren, Dyson, Louise, Hill, Edward M., Tildesley, Michael, Tyson, John R., Hoang, Linda M.N., Galanis, Eleni
Publicado 2023

Single-dose mRNA Vaccine Effectiveness Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Including Alpha and Gamma Variants: A Test-negative Design in Adults 70...

por Skowronski, Danuta M, Setayeshgar, Solmaz, Zou, Macy, Prystajecky, Natalie, Tyson, John R, Galanis, Eleni, Naus, Monika, Patrick, David M, Sbihi, Hind, El Adam, Shiraz, Henry, Bonnie, Hoang, Linda M N, Sadarangani, Manish, Jassem, Agatha N, Krajden, Mel
Publicado 2021

MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry

por Jain, Miten, Tyson, John R., Loose, Matthew, Ip, Camilla L.C., Eccles, David A., O'Grady, Justin, Malla, Sunir, Leggett, Richard M., Wallerman, Ola, Jansen, Hans J., Zalunin, Vadim, Birney, Ewan, Brown, Bonnie L., Snutch, Terrance P., Olsen, Hugh E.
Publicado 2017

Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore

por Tyson, John R, James, Phillip, Stoddart, David, Sparks, Natalie, Wickenhagen, Arthur, Hall, Grant, Choi, Ji Hyun, Lapointe, Hope, Kamelian, Kimia, Smith, Andrew D, Prystajecky, Natalie, Goodfellow, Ian, Wilson, Sam J, Harrigan, Richard, Snutch, Terrance P, Loman, Nicholas J, Quick, Joshua
Publicado 2020

Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January–April 2021

por Hogan, Catherine A., Jassem, Agatha N., Sbihi, Hind, Joffres, Yayuk, Tyson, John R., Noftall, Kyle, Taylor, Marsha, Lee, Tracy, Fjell, Chris, Wilmer, Amanda, Galbraith, John, Romney, Marc G., Henry, Bonnie, Krajden, Mel, Galanis, Eleni, Prystajecky, Natalie, Hoang, Linda M.N.
Publicado 2021

Ca(V)3.2 drives sustained burst‐firing, which is critical for absence seizure propagation in reticular thalamic neurons

por Cain, Stuart M., Tyson, John R., Choi, Hyun‐Beom, Ko, Rebecca, Lin, Paulo J. C., LeDue, Jeffrey M., Powell, Kim L., Bernier, Louis‐Philippe, Rungta, Ravi L., Yang, Yi, Cullis, Pieter R., O'Brien, Terence J., MacVicar, Brian A., Snutch, Terrance P.
Publicado 2018

Comparative Single-Dose mRNA and ChAdOx1 Vaccine Effectiveness Against Severe Acute Respiratory Syndrome Coronavirus 2, Including Variants of Concern: Test-Negative Design, British...

por Skowronski, Danuta M, Setayeshgar, Solmaz, Zou, Macy, Prystajecky, Natalie, Tyson, John R, Sbihi, Hind, Fjell, Chris D, Galanis, Eleni, Naus, Monika, Patrick, David M, El Adam, Shiraz, Ahmed, May A, Kim, Shinhye, Henry, Bonnie, Hoang, Linda M N, Sadarangani, Manish, Jassem, Agatha N, Krajden, Mel
Publicado 2022

Metagenomic analysis of planktonic riverine microbial consortia using nanopore sequencing reveals insight into river microbe taxonomy and function

por Reddington, Kate, Eccles, David, O'Grady, Justin, Drown, Devin M, Hansen, Lars Hestbjerg, Nielsen, Tue Kjærgaard, Ducluzeau, Anne-Lise, Leggett, Richard M, Heavens, Darren, Peel, Ned, Snutch, Terrance P, Bayega, Anthony, Oikonomopoulos, Spyridon, Ragoussis, Jiannis, Barry, Thomas, van der Helm, Eric, Jolic, Dino, Richardson, Hollian, Jansen, Hans, Tyson, John R, Jain, Miten, Brown, Bonnie L
Publicado 2020

Corrigendum to: Metagenomic analysis of planktonic riverine microbial consortia using nanopore sequencing reveals insight into river microbe taxonomy and function

por Reddington, Kate, Eccles, David, O'Grady, Justin, Drown, Devin M, Hansen, Lars Hestbjerg, Nielsen, Tue Kjærgaard, Ducluzeau, Anne-Lise, Leggett, Richard M, Heavens, Darren, Peel, Ned, Snutch, Terrance P, Bayega, Anthony, Oikonomopoulos, Spyridon, Ragoussis, Jiannis, Barry, Thomas, van der Helm, Eric, Jolic, Dino, Richardson, Hollian, Jansen, Hans, Tyson, John R, Jain, Miten, Brown, Bonnie L
Publicado 2020

Nanopore native RNA sequencing of a human poly(A) transcriptome

por Workman, Rachael E., Tang, Alison D., Tang, Paul S., Jain, Miten, Tyson, John R., Razaghi, Roham, Zuzarte, Philip C., Gilpatrick, Timothy, Payne, Alexander, Quick, Joshua, Sadowski, Norah, Holmes, Nadine, de Jesus, Jaqueline Goes, Jones, Karen L., Soulette, Cameron M., Snutch, Terrance P., Loman, Nicholas, Paten, Benedict, Loose, Matthew, Simpson, Jared T., Olsen, Hugh E., Brooks, Angela N., Akeson, Mark, Timp, Winston
Publicado 2019

MinION Analysis and Reference Consortium: Phase 1 data release and analysis

por Ip, Camilla L.C., Loose, Matthew, Tyson, John R., de Cesare, Mariateresa, Brown, Bonnie L., Jain, Miten, Leggett, Richard M., Eccles, David A., Zalunin, Vadim, Urban, John M., Piazza, Paolo, Bowden, Rory J., Paten, Benedict, Mwaigwisya, Solomon, Batty, Elizabeth M., Simpson, Jared T., Snutch, Terrance P., Birney, Ewan, Buck, David, Goodwin, Sara, Jansen, Hans J., O'Grady, Justin, Olsen, Hugh E.
Publicado 2015

Nanopore sequencing and assembly of a human genome with ultra-long reads

por Jain, Miten, Koren, Sergey, Miga, Karen H, Quick, Josh, Rand, Arthur C, Sasani, Thomas A, Tyson, John R, Beggs, Andrew D, Dilthey, Alexander T, Fiddes, Ian T, Malla, Sunir, Marriott, Hannah, Nieto, Tom, O'Grady, Justin, Olsen, Hugh E, Pedersen, Brent S, Rhie, Arang, Richardson, Hollian, Quinlan, Aaron R, Snutch, Terrance P, Tee, Louise, Paten, Benedict, Phillippy, Adam M, Simpson, Jared T, Loman, Nicholas J, Loose, Matthew
Publicado 2018