Keratinocyte death by ferroptosis initiates skin inflammation after UVB exposure

por Vats, Kavita, Kruglov, Oleg, Mizes, Alicia, Samovich, Svetlana N., Amoscato, Andrew A., Tyurin, Vladimir A., Tyurina, Yulia Y., Kagan, Valerian E., Bunimovich, Yuri L.
Publicado 2021

Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes

por Jang, Sehwan, Chapa-Dubocq, Xavier R., Tyurina, Yulia Y., St Croix, Claudette M., Kapralov, Alexandr A., Tyurin, Vladimir A., Bayır, Hülya, Kagan, Valerian E., Javadov, Sabzali
Publicado 2021

The lipase cofactor CGI58 controls placental lipolysis

por Guerrero-Santoro, Jennifer, Morizane, Mayumi, Oh, Soo-Young, Mishima, Takuya, Goff, Julie P., Bildirici, Ibrahim, Sadovsky, Elena, Ouyang, Yingshi, Tyurin, Vladimir A., Tyurina, Yulia Y., Kagan, Valerian E., Sadovsky, Yoel
Publicado 2023

Lipidomics and RNA sequencing reveal a novel subpopulation of nanovesicle within extracellular matrix biomaterials

por Hussey, George S., Pineda Molina, Catalina, Cramer, Madeline C., Tyurina, Yulia Y., Tyurin, Vladimir A., Lee, Yoojin C., El-Mossier, Salma O., Murdock, Mark H., Timashev, Peter S., Kagan, Valerian E., Badylak, Stephen F.
Publicado 2020

A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO(•) sabotage of theft-ferroptosis

por Dar, Haider H., Anthonymuthu, Tamil S., Ponomareva, Liubov A., Souryavong, Austin B., Shurin, Galina V., Kapralov, Alexandr O., Tyurin, Vladimir A., Lee, Janet S., Mallampalli, Rama K., Wenzel, Sally E., Bayir, Hülya, Kagan, Valerian E.
Publicado 2021

Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production

por Kruglov, Oleg, Vats, Kavita, Soman, Vishal, Tyurin, Vladimir A., Tyurina, Yulia Y., Wang, Jiefei, Williams, Li’an, Zhang, Jiying, Donahue Carey, Cara, Jaklitsch, Erik, Chandran, Uma R., Bayir, Hülya, Kagan, Valerian E., Bunimovich, Yuri L.
Publicado 2023

Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression

por Van San, Emily, Debruyne, Angela C., Veeckmans, Geraldine, Tyurina, Yulia Y., Tyurin, Vladimir A., Zheng, Hao, Choi, Sze Men, Augustyns, Koen, van Loo, Geert, Michalke, Bernhard, Venkataramani, Vivek, Toyokuni, Shinya, Bayir, Hülya, Vandenabeele, Peter, Hassannia, Behrouz, Vanden Berghe, Tom
Publicado 2023

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

por Beatty, Alexander, Singh, Tanu, Tyurina, Yulia Y., Tyurin, Vladimir A., Samovich, Svetlana, Nicolas, Emmanuelle, Maslar, Kristen, Zhou, Yan, Cai, Kathy Q., Tan, Yinfei, Doll, Sebastian, Conrad, Marcus, Subramanian, Aravind, Bayır, Hülya, Kagan, Valerian E., Rennefahrt, Ulrike, Peterson, Jeffrey R.
Publicado 2021

Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo

por Tyurina, Yulia Y., Kapralov, Alexandr A., Tyurin, Vladimir A., Shurin, Galina, Amoscato, Andrew A., Rajasundaram, Dhivyaa, Tian, Hua, Bunimovich, Yuri L., Nefedova, Yulia, Herrick, William G., Parchment, Ralph E., Doroshow, James H., Bayir, Hulya, Srivastava, Apurva K., Kagan, Valerian E.
Publicado 2023

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

por Veglia, Filippo, Tyurin, Vladimir A., Mohammadyani, Dariush, Blasi, Maria, Duperret, Elizabeth K., Donthireddy, Laxminarasimha, Hashimoto, Ayumi, Kapralov, Alexandr, Amoscato, Andrew, Angelini, Roberto, Patel, Sima, Alicea-Torres, Kevin, Weiner, David, Murphy, Maureen E., Klein-Seetharaman, Judith, Celis, Esteban, Kagan, Valerian E., Gabrilovich, Dmitry I.
Publicado 2017

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

por Anthonymuthu, Tamil S., Tyurina, Yulia Y., Sun, Wan-Yang, Mikulska-Ruminska, Karolina, Shrivastava, Indira H., Tyurin, Vladimir A., Cinemre, Fatma B., Dar, Haider H., VanDemark, Andrew P., Holman, Theodore R., Sadovsky, Yoel, Stockwell, Brent R., He, Rong-Rong, Bahar, Ivet, Bayır, Hülya, Kagan, Valerian E.
Publicado 2020

Global lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of acute brain injury

por Ji, Jing, Kline, Anthony E, Amoscato, Andrew, Arias, Alejandro S, Sparvero, Louis J, Tyurin, Vladimir A, Tyurina, Yulia Y, Fink, Bruno, Manole, Mioara D, Puccio, Ava M, Okonkwo, David O, Cheng, Jeffrey P, Alexander, Henry, Clark, Robert SB, Kochanek, Patrick M, Wipf, Peter, Kagan, Valerian E, Bayýr, Hülya
Publicado 2012

Redox Epiphospholipidome in Programmed Cell Death Signaling: Catalytic Mechanisms and Regulation

por Kagan, Valerian E., Tyurina, Yulia Y., Vlasova, Irina I., Kapralov, Alexander A., Amoscato, Andrew A., Anthonymuthu, Tamil S., Tyurin, Vladimir A., Shrivastava, Indira H., Cinemre, Fatma B., Lamade, Andrew, Epperly, Michael W., Greenberger, Joel S., Beezhold, Donald H., Mallampalli, Rama K., Srivastava, Apurva K., Bayir, Hulya, Shvedova, Anna A.
Publicado 2021

Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling

por BEDNASH, JOSEPH S., KAGAN, VALERIAN E., ENGLERT, JOSHUA A., FARKAS, DANIELA, TYURINA, YULIA Y., TYURIN, VLADIMIR A., SAMOVICH, SVETLANA N., FARKAS, LASZLO, ELHANCE, AJIT, JOHNS, FINNY, LEE, HYUNWOOK, CHENG, LIJUN, MAJUMDAR, ABHISHEK, JONES, DANIEL, MEJIA, OSCAR ROSAS, RUANE-FOSTER, MARISA, LONDINO, JAMES D., MALLAMPALLI, RAMA K., ROBINSON, RICHARD T.
Publicado 2022

P. aeruginosa augments irradiation injury via 15-lipoxygenase–catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis

por Dar, Haider H., Epperly, Michael W., Tyurin, Vladimir A., Amoscato, Andrew A., Anthonymuthu, Tamil S., Souryavong, Austin B., Kapralov, Alexander A., Shurin, Galina V., Samovich, Svetlana N., St. Croix, Claudette M., Watkins, Simon C., Wenzel, Sally E., Mallampalli, Rama K., Greenberger, Joel S., Bayır, Hülya, Kagan, Valerian E., Tyurina, Yulia Y.
Publicado 2022

Lipid accumulation and dendritic cell dysfunction in cancer

por Herber, Donna L., Cao, Wei, Nefedova, Yulia, Novitskiy, Sergey V., Nagaraj, Srinivas, Tyurin, Vladimir A., Corzo, Alex, Cho, Hyun Il, Celis, Esteban, Lennox, Briana, Knight, Stella C., Padhya, Tapan, McCaffrey, Thomas V., McCaffrey, Judith C., Antonia, Scott, Fishman, Mayer, Ferris, Robert L., Kagan, Valerian E., Gabrilovich, Dmitry I.
Publicado 2010

mitochondrial pathway for biosynthesis of lipid mediators

por Tyurina, Yulia Y., Poloyac, Samuel M., Tyurin, Vladimir A., Kapralov, Alexander A., Jiang, Jianfei, Anthonymuthu, Tamil Selvan, Kapralova, Valentina I., Vikulina, Anna S., Jung, Mi-Yeon, Epperly, Michael W., Mohammadyani, Dariush, Klein-Seetharaman, Judith, Jackson, Travis C., Kochanek, Patrick M., Pitt, Bruce R., Greenberger, Joel S., Vladimirov, Yury A., Bayır, Hülya, Kagan, Valerian E.
Publicado 2014

Fatty acid transporter 2 reprograms neutrophils in cancer

por Veglia, Filippo, Tyurin, Vladimir A., Blasi, Maria, De Leo, Alessandra, Kossenkov, Andrew, Donthireddy, Laxminarasimha, Jerrick, To Tsun Ki, Schug, Zach, Basu, Subhasree, Wang, Fang, Ricciotti, Emanuela, DiRusso, Concetta, Murphy, Maureen E., Vonderheide, Robert H., Lieberman, Paul M., Mulligan, Charles, Nam, Brian, Hockstein, Neil, Masters, Gregory, Guarino, Michael, Lin, Cindy, Nefedova, Yulia, Black, Paul, Kagan, Valerian E., Gabrilovich, Dmitry
Publicado 2019

Necroptosis triggers spatially restricted neutrophil-mediated vascular damage during lung ischemia reperfusion injury

por Li, Wenjun, Terada, Yuriko, Tyurina, Yulia Y., Tyurin, Vladimir A., Bery, Amit I., Gauthier, Jason M., Higashikubo, Ryuji, Tong, Alice Y., Zhou, Dequan, Nunez-Santana, Felix, Lecuona, Emilia, Hassan, Adil, Hashimoto, Kohei, Scozzi, Davide, Puri, Varun, Nava, Ruben G., Krupnick, Alexander S., Lavine, Kory J., Gelman, Andrew E., Miller, Mark J., Kagan, Valerian E., Bharat, Ankit, Kreisel, Daniel
Publicado 2022

A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation induced death

por Atkinson, Jeffrey, Kapralov, Alexandr A., Yanamala, Naveena, Tyurina, Yulia Y., Amoscato, Andrew A., Pearce, Linda, Peterson, Jim, Huang, Zhentai, Jiang, Jianfei, Samhan-Arias, Alejandro K., Maeda, Akihiro, Feng, Weihong, Wasserloos, Karla, Belikova, Natalia A., Tyurin, Vladimir A., Wang, Hong, Fletcher, Jackie, Wang, Yongsheng, Vlasova, Irina I., Klein-Seetharaman, Judith, Stoyanovsky, Detcho A., Bayîr, Hülya, Pitt, Bruce R., Epperly, Michael W., Greenberger, Joel S., Kagan, Valerian E.
Publicado 2011